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M Phase Cell Cycle Checkpoints
Microtubule dynamics and the movement of chromosomes.
Differential expression of a phosphoepitope at the kinetochores of moving chromosomes.
Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
The reversibility of mitotic exit in vertebrate cells.
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.
Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
Microtubule distribution in cultured cells and intact tissues: improved immunolabeling resolution through the use of reversible embedment cytochemistry.
The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183.
Chromosome Movement in Prometaphase
PROTEIN ABLATION MICROSCOPE
Understanding Cell Division
The Spindle Checkpoint as a Target for Cancer