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Gorbsky, Gary

One or more keywords matched the following items that are connected to Gorbsky, Gary

Item Type	Name
Concept	Cell Cycle
Concept	Cell Cycle Proteins
Concept	Cell Cycle Checkpoints
Concept	M Phase Cell Cycle Checkpoints
Academic Article	Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.
Academic Article	The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
Academic Article	Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.
Academic Article	Multiple determinants and consequences of cohesion fatigue in mammalian cells.
Academic Article	Mitotic phosphoepitopes are expressed in Kc cells, neuroblasts and isolated chromosomes of Drosophila melanogaster.
Academic Article	MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.
Academic Article	Cohesion fatigue induces chromatid separation in cells delayed at metaphase.
Academic Article	The spindle checkpoint and chromosome segregation in meiosis.
Academic Article	Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase.
Academic Article	Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
Academic Article	Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
Academic Article	Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.
Academic Article	Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.
Academic Article	Fine tuning the cell cycle: activation of the Cdk1 inhibitory phosphorylation pathway during mitotic exit.
Academic Article	Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
Academic Article	Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
Academic Article	Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
Academic Article	Spatiotemporal regulation of the anaphase-promoting complex in mitosis.
Academic Article	The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Academic Article	Predictive bioinformatics identifies novel regulators of proliferation in a cancer stem cell model.
Academic Article	Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).
Academic Article	Cell cycle checkpoints: arresting progress in mitosis.
Academic Article	Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis.
Academic Article	The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
Academic Article	The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.
Academic Article	Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
Academic Article	Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.
Academic Article	The dynamics of DNA topoisomerase IIalpha in living cells.
Academic Article	Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
Academic Article	The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
Academic Article	The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183.
Academic Article	Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.
Academic Article	Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
Grant	Chromosome Movement in Prometaphase
Grant	The role of cohesion fatigue in chromosome instability
Grant	The Spindle Checkpoint as a Target for Cancer

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Cell Cycle