| Item Type | Name |
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Concept
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Mitosis
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Academic Article
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Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.
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Academic Article
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The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
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Academic Article
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Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions.
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Academic Article
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Regulation of microtubule stability and mitotic progression by survivin.
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Academic Article
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Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint.
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Academic Article
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Live-cell fluorescence imaging for phenotypic analysis of mitosis.
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Academic Article
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Multiple determinants and consequences of cohesion fatigue in mammalian cells.
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Academic Article
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CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation.
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Academic Article
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Differential expression of a phosphoepitope at the kinetochores of moving chromosomes.
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Academic Article
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DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2.
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Academic Article
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Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.
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Academic Article
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Mitotic phosphoepitopes are expressed in Kc cells, neuroblasts and isolated chromosomes of Drosophila melanogaster.
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Academic Article
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MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.
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Academic Article
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Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis.
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Academic Article
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Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis.
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Academic Article
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Both alpha and beta isoforms of mammalian DNA topoisomerase II associate with chromosomes in mitosis.
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Academic Article
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Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
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Academic Article
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The reversibility of mitotic exit in vertebrate cells.
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Academic Article
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The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.
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Academic Article
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Chromosome motion in mitosis.
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Academic Article
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Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase.
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Academic Article
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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
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Academic Article
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Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
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Academic Article
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Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.
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Academic Article
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Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.
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Academic Article
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Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro.
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Academic Article
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A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.
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Academic Article
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Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
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Academic Article
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Duct tape for broken chromosomes.
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Academic Article
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Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
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Academic Article
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Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
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Academic Article
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Spatiotemporal regulation of the anaphase-promoting complex in mitosis.
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Academic Article
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Cell cycle checkpoints: arresting progress in mitosis.
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Academic Article
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Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E.
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Academic Article
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Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody.
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Academic Article
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Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.
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Academic Article
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Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis.
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Academic Article
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The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
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Academic Article
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The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.
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Academic Article
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Mitosis: MCAK under the aura of Aurora B.
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Academic Article
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Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
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Academic Article
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Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
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Academic Article
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Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.
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Academic Article
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The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
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Academic Article
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CSAG1 maintains the integrity of the mitotic centrosome in cells with defective p53.
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Academic Article
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Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.
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Academic Article
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Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
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Grant
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Chromosome Movement in Prometaphase
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Grant
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The role of cohesion fatigue in chromosome instability
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Grant
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PROTEIN ABLATION MICROSCOPE
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Grant
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The Spindle Checkpoint as a Target for Cancer
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Grant
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A Cell Dynamics Microscope for Live Cell Fluorescence
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Academic Article
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More than two populations of microtubules comprise the dynamic mitotic spindle.
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Academic Article
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Live Fluorescence Imaging of Chromosome Segregation in Cultured Cells.
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