| Item Type | Name |
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Concept
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Antigen-Presenting Cells
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Concept
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Antigens, Differentiation, B-Lymphocyte
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Concept
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Blood Cells
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Concept
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B-Lymphocytes
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Concept
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Bone Marrow Cells
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Concept
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Dendritic Cells
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Concept
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Clone Cells
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Concept
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Epithelial Cells
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Concept
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T-Lymphocytes, Helper-Inducer
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Concept
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Hematopoietic Stem Cells
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Concept
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Lymphocytes
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Concept
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Plasma Cells
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Concept
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T-Lymphocytes
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Concept
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T-Lymphocytes, Cytotoxic
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Concept
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Receptors, Antigen, B-Cell
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Concept
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Th1 Cells
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Concept
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HL-60 Cells
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Concept
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Epitopes, B-Lymphocyte
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Concept
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Lymphoma, B-Cell
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Concept
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3T3 Cells
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Concept
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Jurkat Cells
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Concept
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U937 Cells
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Concept
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Tumor Cells, Cultured
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Concept
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Multipotent Stem Cells
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Concept
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Alveolar Epithelial Cells
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Concept
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COS Cells
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Concept
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HEK293 Cells
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Concept
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Myeloid Cells
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Concept
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Cells, Cultured
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Concept
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Mast Cells
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Academic Article
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Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.
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Academic Article
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Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood.
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Academic Article
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Negative signaling in B cells: SHIP Grbs Shc.
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Academic Article
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Bovine luteal cells elicit major histocompatibility complex class II-dependent T-cell proliferation.
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Academic Article
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Protein interactions of Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP): association with Shc displaces SHIP from FcgammaRIIb in B cells.
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Academic Article
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FcgammaRIIb modulation of surface immunoglobulin-induced Akt activation in murine B cells.
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Academic Article
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The SH2-containing 5'-inositol phosphatase (SHIP) is tyrosine phosphorylated after Fc gamma receptor clustering in monocytes.
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Academic Article
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Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.
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Academic Article
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Negative signaling in health and disease.
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Academic Article
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Activation of nuclear factor of activated T cells by human T-lymphotropic virus type 1 accessory protein p12(I).
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Academic Article
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Convergence of signaling pathways on the activation of ERK in B cells.
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Academic Article
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Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.
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Academic Article
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Anti-peptidoglycan antibodies and Fc? receptors are the key mediators of inflammation in Gram-positive sepsis.
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Academic Article
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Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice.
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Academic Article
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Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking.
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Academic Article
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Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes.
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Academic Article
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T cell receptor aggregation, but not dimerization, induces increased cytosolic calcium concentrations and reveals a lack of stable association between CD4 and the T cell receptor.
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Academic Article
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Stimulation of PIP2 hydrolysis by aluminum fluoride in resting T cell subsets of normal and autoimmune-prone lpr mice.
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Academic Article
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Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase.
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Academic Article
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Coupling of B cell surface Ig, Ia and BSF1 receptors to intracellular "second messengers".
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Academic Article
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B cell activation. VIII. Membrane immunoglobulins transduce signals via activation of phosphatidylinositol hydrolysis.
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Academic Article
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The role of p56lck in CD4-mediated suppression of CD3-induced early signaling events in T lymphocytes.
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Academic Article
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Negative signaling via FcgammaRIIB1 in B cells blocks phospholipase Cgamma2 tyrosine phosphorylation but not Syk or Lyn activation.
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Academic Article
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Activation-induced bi-dentate interaction of SHIP and Shc in B lymphocytes.
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Academic Article
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Role of SHIP in FcgammaRIIb-mediated inhibition of Ras activation in B cells.
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Academic Article
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Positive and negative signaling in B lymphocytes.
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Academic Article
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Adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2.
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Academic Article
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Src homology 2-containing 5-inositol phosphatase (SHIP) suppresses an early stage of lymphoid cell development through elevated interleukin-6 production by myeloid cells in bone marrow.
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Academic Article
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IL-6 blocks a discrete early step in lymphopoiesis.
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Academic Article
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Human lung innate immune cytokine response to adenovirus type 7.
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Academic Article
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Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models.
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Academic Article
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Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2.
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Academic Article
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Molecular events mediating T cell activation.
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Academic Article
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T lymphocyte activation: a biological model of signal transduction.
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Academic Article
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B cell activation. VI. Effects of exogenous diglyceride and modulators of phospholipid metabolism suggest a central role for diacylglycerol generation in transmembrane signaling by mIg.
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Academic Article
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Translocation of protein kinase C during membrane immunoglobulin-mediated transmembrane signaling in B lymphocytes.
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Academic Article
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Differential transmembrane signaling in B lymphocyte activation.
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Academic Article
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Expression and biochemical characterization of human protein kinase C-theta.
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Academic Article
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Construction and characterization of lck- and fyn-specific tRNA: ribozyme chimeras.
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Academic Article
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Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP.
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Academic Article
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Activation of the Ras signaling pathway by the CD40 receptor.
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Academic Article
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Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway.
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Academic Article
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Activation of Src-family tyrosine kinases during Fas-induced apoptosis.
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Academic Article
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Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis.
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Academic Article
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Inhibitory signaling by B cell Fc gamma RIIb.
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Academic Article
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Chimeric receptors composed of phosphoinositide 3-kinase domains and FCgamma receptor ligand-binding domains mediate phagocytosis in COS fibroblasts.
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Academic Article
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GM1 inhibits early signaling events mediated by PDGF receptor in cultured human glioma cells.
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Academic Article
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Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis.
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Academic Article
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Enzymatic activity of the Src homology 2 domain-containing inositol phosphatase is regulated by a plasma membrane location.
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Academic Article
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The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells.
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Academic Article
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Signal transduction by human-restricted Fc gamma RIIa involves three distinct cytoplasmic kinase families leading to phagocytosis.
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Academic Article
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The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors.
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Academic Article
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Adenovirus type 7 induces interleukin-8 in a lung slice model and requires activation of Erk.
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Academic Article
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Vav activation and function as a rac guanine nucleotide exchange factor in macrophage colony-stimulating factor-induced macrophage chemotaxis.
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Academic Article
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A unique CD72 epitope suggests a potential interaction with Fc gamma RII/CD32 on B lineage lymphocytes.
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Academic Article
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T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation.
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Academic Article
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B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.
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Academic Article
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The role of protein kinase C in the cytotoxic T-cell lytic response.
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Academic Article
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Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan.
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Academic Article
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Tyrosine phosphorylation and activation of Vav GTP/GDP exchange activity in antigen receptor-triggered B cells.
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Academic Article
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Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.
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Academic Article
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L-selectin activates the Ras pathway via the tyrosine kinase p56lck.
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Academic Article
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Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions.
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Academic Article
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Visualization of negative signaling in B cells by quantitative confocal microscopy.
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Academic Article
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C-reactive protein induces signaling through Fc gamma RIIa on HL-60 granulocytes.
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Academic Article
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Regulation of signal transduction by the Fc gamma receptor family members and their involvement in autoimmunity.
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Academic Article
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Negative signaling.
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Academic Article
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How do inhibitory phosphatases work?
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Academic Article
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CD95 rapidly clusters in cells of diverse origins.
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Academic Article
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Human lung innate immune response to Bacillus anthracis spore infection.
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Academic Article
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Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals.
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Academic Article
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Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages.
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Academic Article
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Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-alpha and NF-kappab are key components of the innate immune response to the pathogen.
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Academic Article
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IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production.
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Academic Article
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Cutting edge: primary innate immune cells respond efficiently to polymeric peptidoglycan, but not to peptidoglycan monomers.
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Academic Article
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Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines.
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Academic Article
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Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.
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Academic Article
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Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase.
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Academic Article
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Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.
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Academic Article
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Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation.
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Academic Article
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Molecular analysis of Ras activation by tyrosine phosphorylated Vav.
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Academic Article
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Recruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fc gamma immunoreceptor tyrosine-based inhibition motif peptide motif.
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Academic Article
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Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1? and Promote TH17 Cell Differentiation.
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