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Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients.
Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes.
Glucose "peak" and glucose "spike": Impact on endothelial function and oxidative stress.
Clinical review 2: The "metabolic memory": is more than just tight glucose control necessary to prevent diabetic complications?
Long-term glycemic control influences the long-lasting effect of hyperglycemia on endothelial function in type 1 diabetes.
'Glycaemic variability': a new therapeutic challenge in diabetes and the critical care setting.
Effect of acute hyperglycaemia, long-term glycaemic control and insulin on endothelial dysfunction and inflammation in Type 1 diabetic patients with different characteristics.
Oxidative stress is, convincingly, the mediator of the dangerous effects of glucose variability.
Hypothesis: the 'metabolic memory', the new challenge of diabetes.
Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling.
Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.