| Item Type | Name |
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Concept
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Blood-Brain Barrier
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Concept
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Brain
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Concept
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Brain Chemistry
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Concept
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Brain Edema
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Concept
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Brain Injuries
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Concept
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Brain Mapping
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Concept
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Brain Ischemia
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Academic Article
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Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.
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Academic Article
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Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint.
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Academic Article
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Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
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Academic Article
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Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats.
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Academic Article
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Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals.
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Academic Article
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The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing.
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Academic Article
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Caloric restricted male rats demonstrate fewer synapses in layer 2 of sensorimotor cortex.
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Academic Article
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Microvascular plasticity in aging.
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Academic Article
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Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems.
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Academic Article
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Stability of local brain levels of insulin-like growth factor-I in two well-characterized models of decreased plasma IGF-I.
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Academic Article
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Radiation attenuates physiological angiogenesis by differential expression of VEGF, Ang-1, tie-2 and Ang-2 in rat brain.
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Academic Article
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Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia.
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Academic Article
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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
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Academic Article
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Whole brain radiation-induced cognitive impairment: pathophysiological mechanisms and therapeutic targets.
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Academic Article
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Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
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Academic Article
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Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
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Academic Article
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Growth hormone, insulin-like growth factor-1 and the aging brain.
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Academic Article
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Brain and cerebrovascular aging--new mechanisms and insights.
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Academic Article
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CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging.
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Academic Article
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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
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Academic Article
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Role of NADPH oxidase in radiation-induced pro-oxidative and pro-inflammatory pathways in mouse brain.
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Academic Article
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Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8+ tissue-resident memory T cells in a miR-155-dependent fashion.
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Academic Article
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Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth.
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Academic Article
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Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus.
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Academic Article
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The ependymal route for insulin-like growth factor-1 gene therapy in the brain.
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Academic Article
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Irradiation alters MMP-2/TIMP-2 system and collagen type IV degradation in brain.
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Academic Article
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Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
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Academic Article
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Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
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Academic Article
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Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
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Academic Article
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
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Academic Article
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Attenuation of Fos-like immunoreactivity induced by a single electroconvulsive shock in brains of aging mice.
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Academic Article
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Increased secretion of somatostatin-28 from hypothalamic neurons of aged rats in vitro.
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Academic Article
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Effect of in utero ethanol exposure on the postnatal ontogeny of insulin-like growth factor-1, and type-1 and type-2 insulin-like growth factor receptors in the rat brain.
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Academic Article
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Distribution and levels of insulin-like growth factor I mRNA across the life span in the Brown Norway x Fischer 344 rat brain.
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Academic Article
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Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats.
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Academic Article
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Chronic [D-Ala2]-growth hormone-releasing hormone administration attenuates age-related deficits in spatial memory.
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Academic Article
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Irradiation induces regionally specific alterations in pro-inflammatory environments in rat brain.
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Academic Article
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Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence.
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Academic Article
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Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.
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Academic Article
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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
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Academic Article
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Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
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Academic Article
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Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
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Academic Article
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Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
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Academic Article
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IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
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Academic Article
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Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
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Academic Article
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Comparison of protein synthesis in brain and peripheral tissue during aging. Relationship to insulin-like growth factor-1 and type 1 IGF receptors.
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Academic Article
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Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice.
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Academic Article
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Age-related synaptic changes in sensorimotor cortex of the Brown Norway X fischer 344 rat.
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Academic Article
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Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging.
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Academic Article
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Growth hormone and IGF-I modulate local cerebral glucose utilization and ATP levels in a model of adult-onset growth hormone deficiency.
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Academic Article
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Aging attenuates radiation-induced expression of pro-inflammatory mediators in rat brain.
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Academic Article
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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
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Academic Article
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IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
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Academic Article
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Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
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Grant
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Cognitive Decline &Protein Expression Profiles in Aging
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Grant
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Effects of Radiation on Brain Microvasculature and Cognition
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Grant
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NOVEL APPROACHES FOR REGULATION OF IGF-1 LEVELS THROUGHOUT THE LIFESPAN
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Grant
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GROWTH HORMONE (GH) AND GH-DEPENDENT BIOMARKERS OF AGING
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Grant
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Growth Hormone &IGF-1 in CNS and Cerebrovascular Aging
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Grant
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CHRONIC ETHANOL, GROWTH HORMONE AND PROTEIN SYNTHESIS
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Academic Article
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IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
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Academic Article
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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
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Academic Article
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Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study.
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Academic Article
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
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Academic Article
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Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
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Academic Article
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Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment.
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Academic Article
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Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
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Academic Article
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Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease.
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