Item Type | Name |
Concept
|
Alzheimer Disease
|
Concept
|
Cardiovascular Diseases
|
Concept
|
Chronic Disease
|
Concept
|
Coronary Artery Disease
|
Concept
|
Heart Diseases
|
Concept
|
Nervous System Diseases
|
Concept
|
Vascular Diseases
|
Concept
|
Disease Progression
|
Concept
|
Disease Transmission, Infectious
|
Concept
|
Peripheral Vascular Diseases
|
Concept
|
Peripheral Arterial Disease
|
Concept
|
Disease Models, Animal
|
Concept
|
Infant, Premature, Diseases
|
Academic Article
|
Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
|
Academic Article
|
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
|
Academic Article
|
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
|
Academic Article
|
Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
|
Academic Article
|
Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
|
Academic Article
|
Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice.
|
Academic Article
|
Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
|
Academic Article
|
Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
|
Academic Article
|
Age-related decline in peripheral vascular health predicts cognitive impairment.
|
Academic Article
|
Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
|
Academic Article
|
Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
|
Academic Article
|
Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
|
Academic Article
|
Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle.
|
Academic Article
|
Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation.
|
Academic Article
|
Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.
|
Academic Article
|
Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury.
|
Academic Article
|
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
|
Academic Article
|
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy.
|
Academic Article
|
Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
|
Academic Article
|
Novel organotypic in vitro slice culture model for intraventricular hemorrhage of premature infants.
|
Academic Article
|
Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
|
Academic Article
|
Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease.
|
Academic Article
|
Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
|
Academic Article
|
Pharmacological Strategies to Retard Cardiovascular Aging.
|
Academic Article
|
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
|
Academic Article
|
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
|
Academic Article
|
Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
|
Academic Article
|
Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.
|
Academic Article
|
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
|
Academic Article
|
Endothelium-derived bone morphogenic protein antagonists may counteract the proatherogenic vascular effects of bone morphogenic protein 4.
|
Academic Article
|
Mechanisms of vascular aging: new perspectives.
|
Academic Article
|
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
|
Academic Article
|
Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease.
|
Academic Article
|
Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
|
Academic Article
|
INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE.
|
Academic Article
|
Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
|
Academic Article
|
Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
|
Academic Article
|
Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.
|
Academic Article
|
Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies.
|
Academic Article
|
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
|
Academic Article
|
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
|
Academic Article
|
Assessment of endothelial function in leptomeningeal arterioles derived from patients with Alzheimer's disease and vascular cognitive impairment.
|
Academic Article
|
Mechanisms of Vascular Aging.
|
Academic Article
|
CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
|
Academic Article
|
Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis.
|
Academic Article
|
Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease.
|
Academic Article
|
Altered mitochondrial energy metabolism may play a role in vascular aging.
|
Academic Article
|
Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance.
|
Academic Article
|
Oxidative stress in vascular senescence: lessons from successfully aging species.
|
Academic Article
|
Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
|
Academic Article
|
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.
|
Academic Article
|
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
|
Academic Article
|
Consequences of intraventricular hemorrhage in a rabbit pup model.
|
Academic Article
|
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
|
Academic Article
|
Mitochondria and aging in the vascular system.
|
Academic Article
|
Mitochondria and cardiovascular aging.
|
Academic Article
|
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
|
Academic Article
|
Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
|
Academic Article
|
Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease.
|
Academic Article
|
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
|
Academic Article
|
Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
|
Academic Article
|
AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage.
|
Academic Article
|
Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
|
Academic Article
|
GeroScience: understanding the interaction of processes of aging and chronic diseases.
|
Academic Article
|
Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies.
|
Academic Article
|
Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions.
|
Academic Article
|
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.
|
Academic Article
|
Resveratrol inhibits aggregation of platelets from high-risk cardiac patients with aspirin resistance.
|
Academic Article
|
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
|
Academic Article
|
Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
|
Academic Article
|
Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al.
|
Academic Article
|
Intraventricular hemorrhage induces deposition of proteoglycans in premature rabbits, but their in vivo degradation with chondroitinase does not restore myelination, ventricle size and neurological recovery.
|
Academic Article
|
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
|
Academic Article
|
Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
|
Academic Article
|
Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart.
|
Academic Article
|
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
|
Academic Article
|
Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
|
Academic Article
|
Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
|
Academic Article
|
IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
|
Academic Article
|
Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease.
|
Academic Article
|
Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.
|
Academic Article
|
Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
|
Academic Article
|
Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.
|
Academic Article
|
Companion animals likely do not spread COVID-19 but may get infected themselves.
|
Academic Article
|
Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease.
|
Grant
|
Hemodynamic forces regulate BMPs in coronary arteries
|
Academic Article
|
Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition.
|
Academic Article
|
Hypertension-induced cognitive impairment: from pathophysiology to public health.
|
Academic Article
|
Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
|
Academic Article
|
Cognitive decrement in older adults with symptomatic peripheral artery disease.
|
Academic Article
|
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
|