Item Type | Name |
Concept
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Endothelium
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Concept
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Endothelium, Vascular
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Academic Article
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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
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Academic Article
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Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
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Academic Article
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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
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Academic Article
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Obesity-induced cognitive impairment in older adults: a microvascular perspective.
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Academic Article
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Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
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Academic Article
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Age-related decline in peripheral vascular health predicts cognitive impairment.
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Academic Article
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Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
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Academic Article
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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
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Academic Article
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Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
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Academic Article
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Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle.
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Academic Article
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Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation.
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Academic Article
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Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.
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Academic Article
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Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
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Academic Article
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Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.
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Academic Article
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Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
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Academic Article
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Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
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Academic Article
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Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity.
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Academic Article
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Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener.
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Academic Article
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Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries.
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Academic Article
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Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
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Academic Article
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Endothelium-derived bone morphogenic protein antagonists may counteract the proatherogenic vascular effects of bone morphogenic protein 4.
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Academic Article
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Resveratrol induces mitochondrial biogenesis in endothelial cells.
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Academic Article
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Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.
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Academic Article
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Mechanisms of vascular aging: new perspectives.
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Academic Article
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Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain.
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Academic Article
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Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
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Academic Article
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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
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Academic Article
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Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C.
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Academic Article
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Role of endothelial [Ca2+]i in activation of eNOS in pressurized arterioles by agonists and wall shear stress.
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Academic Article
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Mediation of EDHF-induced reduction of smooth muscle [Ca(2+)](i) and arteriolar dilation by K(+) channels, 5,6-EET, and gap junctions.
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Academic Article
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Increased NO-mediated and reduced TxA2-dependent responses in skeletal muscle arterioles in pregnancy.
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Academic Article
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High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.
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Academic Article
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Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
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Academic Article
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Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
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Academic Article
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Altered mitochondrial energy metabolism may play a role in vascular aging.
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Academic Article
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Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
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Academic Article
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Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling.
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Academic Article
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Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
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Academic Article
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Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
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Academic Article
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Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
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Academic Article
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Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
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Academic Article
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Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
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Academic Article
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Mitochondria and aging in the vascular system.
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Academic Article
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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
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Academic Article
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Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
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Academic Article
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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
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Academic Article
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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
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Academic Article
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Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
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Academic Article
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Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?
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Academic Article
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Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.
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Academic Article
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Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.
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Academic Article
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The aging kidney: role of endothelial oxidative stress and inflammation.
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Academic Article
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Vascular aging in the longest-living rodent, the naked mole rat.
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Academic Article
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Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
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Grant
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Hemodynamic forces regulate BMPs in coronary arteries
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Academic Article
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
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