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Ungvari, Zoltan
One or more keywords matched the following items that are connected to Ungvari, Zoltan
Item TypeName
Concept Mice, Inbred C57BL
Concept Mice, Inbred ICR
Concept Mice, Inbred Strains
Concept Mice, Mutant Strains
Concept Mice, Obese
Concept Mice, Transgenic
Concept Mice, Knockout
Concept Mice
Concept Mice, 129 Strain
Academic Article Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Academic Article Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
Academic Article Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Academic Article Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
Academic Article Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
Academic Article Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
Academic Article Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice.
Academic Article Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
Academic Article Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
Academic Article Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
Academic Article Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
Academic Article Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
Academic Article Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
Academic Article Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
Academic Article Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
Academic Article Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
Academic Article Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
Academic Article Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency.
Academic Article Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
Academic Article Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
Academic Article Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Academic Article Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
Academic Article Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
Academic Article Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
Academic Article Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice.
Academic Article CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
Academic Article Resveratrol induces mitochondrial biogenesis in endothelial cells.
Academic Article Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.
Academic Article SRT1720 improves survival and healthspan of obese mice.
Academic Article The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
Academic Article Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
Academic Article Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
Academic Article Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
Academic Article Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
Academic Article The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
Academic Article Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Academic Article Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
Academic Article Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.
Academic Article Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
Academic Article Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
Academic Article IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Academic Article Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
Academic Article CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
Academic Article Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
Academic Article Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
Academic Article Oxidative stress in vascular senescence: lessons from successfully aging species.
Academic Article Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Academic Article The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.
Academic Article Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
Academic Article Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
Academic Article Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
Academic Article Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Academic Article Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
Academic Article Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
Academic Article IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
Academic Article Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
Academic Article Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
Academic Article Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.
Academic Article Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies.
Academic Article Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
Academic Article Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
Academic Article Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
Academic Article Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
Academic Article Mitochondrial protection by resveratrol.
Academic Article Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Academic Article Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
Academic Article IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Academic Article Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
Academic Article Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
Academic Article IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
Academic Article IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Academic Article IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
Academic Article Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
Academic Article Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.
Academic Article Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
Academic Article Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.
Academic Article Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease.
Academic Article Midlife Obesity Impairs Neurovascular Coupling Responses.
Grant Cerebral microhemorrhages and gait dysfunction in aging
Grant Role of SIRT1 in vasoprotection
Grant Radiation-induced astrocyte dysfunction and cognitive decline
Academic Article IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
Academic Article Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography.
Academic Article Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis.
Grant Cerebromicrovascular rejuvenation by heterochronic blood exchange
Academic Article Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
Academic Article Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
Academic Article Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
Academic Article Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission.
Academic Article Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
Academic Article Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging.
Academic Article Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
Academic Article Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
Academic Article Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
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