| Item Type | Name |
|
Concept
|
Rats, Inbred BN
|
|
Concept
|
Rats, Inbred F344
|
|
Concept
|
Rats, Inbred Lew
|
|
Concept
|
Rats, Inbred SHR
|
|
Concept
|
Rats, Inbred WKY
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Rats, Zucker
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Rats
|
|
Concept
|
Mole Rats
|
|
Academic Article
|
Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
|
|
Academic Article
|
Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
|
|
Academic Article
|
Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
|
|
Academic Article
|
Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|
|
Academic Article
|
Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any?
|
|
Academic Article
|
Electrophysiological effects of homocysteine in isolated rat right ventricular papillary muscles and left atria.
|
|
Academic Article
|
Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle.
|
|
Academic Article
|
Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation.
|
|
Academic Article
|
Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.
|
|
Academic Article
|
Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.
|
|
Academic Article
|
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
|
|
Academic Article
|
Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
|
|
Academic Article
|
Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.
|
|
Academic Article
|
Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
|
|
Academic Article
|
Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
|
|
Academic Article
|
Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
|
|
Academic Article
|
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
|
|
Academic Article
|
Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
|
|
Academic Article
|
Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity.
|
|
Academic Article
|
Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia.
|
|
Academic Article
|
Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener.
|
|
Academic Article
|
Homocysteine reduces smooth muscle [Ca2+]i and constrictor responses of isolated arterioles.
|
|
Academic Article
|
Selected contribution: NO released to flow reduces myogenic tone of skeletal muscle arterioles by decreasing smooth muscle Ca(2+) sensitivity.
|
|
Academic Article
|
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
|
|
Academic Article
|
Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.
|
|
Academic Article
|
Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries.
|
|
Academic Article
|
Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.
|
|
Academic Article
|
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
|
|
Academic Article
|
Resveratrol increases vascular oxidative stress resistance.
|
|
Academic Article
|
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
|
|
Academic Article
|
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.
|
|
Academic Article
|
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
|
|
Academic Article
|
Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
|
|
Academic Article
|
Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
|
|
Academic Article
|
Biotin-conjugated fusogenic liposomes for high-quality cell purification.
|
|
Academic Article
|
The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
|
|
Academic Article
|
Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats.
|
|
Academic Article
|
Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31.
|
|
Academic Article
|
Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C.
|
|
Academic Article
|
Simultaneously increased TxA(2) activity in isolated arterioles and platelets of rats with hyperhomocysteinemia.
|
|
Academic Article
|
Role of endothelial [Ca2+]i in activation of eNOS in pressurized arterioles by agonists and wall shear stress.
|
|
Academic Article
|
Mediation of EDHF-induced reduction of smooth muscle [Ca(2+)](i) and arteriolar dilation by K(+) channels, 5,6-EET, and gap junctions.
|
|
Academic Article
|
High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.
|
|
Academic Article
|
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
|
|
Academic Article
|
Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
|
|
Academic Article
|
Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway.
|
|
Academic Article
|
Oxidative stress in vascular senescence: lessons from successfully aging species.
|
|
Academic Article
|
Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.
|
|
Academic Article
|
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
|
|
Academic Article
|
Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
|
|
Academic Article
|
Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
|
|
Academic Article
|
Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
|
|
Academic Article
|
Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
|
|
Academic Article
|
Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
|
|
Academic Article
|
Review of cardiovascular effects of fluoxetine, a selective serotonin reuptake inhibitor, compared to tricyclic antidepressants.
|
|
Academic Article
|
Serotonin reuptake inhibitor fluoxetine decreases arteriolar myogenic tone by reducing smooth muscle [Ca2+]i.
|
|
Academic Article
|
Xanthine oxidase-derived reactive oxygen species convert flow-induced arteriolar dilation to constriction in hyperhomocysteinemia: possible role of peroxynitrite.
|
|
Academic Article
|
Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists.
|
|
Academic Article
|
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
|
|
Academic Article
|
Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?
|
|
Academic Article
|
Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.
|
|
Academic Article
|
Vascular aging in the longest-living rodent, the naked mole rat.
|
|
Academic Article
|
Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.
|
|
Academic Article
|
Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
|
|
Academic Article
|
Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
|
|
Academic Article
|
Age-related impairment of metabovascular coupling during cortical spreading depolarizations.
|
|
Grant
|
Hemodynamic forces regulate BMPs in coronary arteries
|