| Item Type | Name |
|
Concept
|
Neurovascular Coupling
|
|
Concept
|
Intravital Microscopy
|
|
Concept
|
Academies and Institutes
|
|
Concept
|
Accidental Falls
|
|
Concept
|
Cognitive Aging
|
|
Concept
|
Calcimycin
|
|
Concept
|
Glycogen Synthase Kinase 3 beta
|
|
Concept
|
Soluble Guanylyl Cyclase
|
|
Concept
|
Kelch-Like ECH-Associated Protein 1
|
|
Concept
|
Superoxide Dismutase-1
|
|
Concept
|
Receptor for Advanced Glycation End Products
|
|
Concept
|
Poly(ADP-ribose) Polymerase Inhibitors
|
|
Concept
|
Adenylyl Cyclase Inhibitors
|
|
Concept
|
ADAM17 Protein
|
|
Concept
|
Brain Injuries, Traumatic
|
|
Concept
|
Celecoxib
|
|
Concept
|
Etanercept
|
|
Concept
|
Serum Amyloid P-Component
|
|
Concept
|
Adenoviridae
|
|
Concept
|
Adipose Tissue
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Administration, Oral
|
|
Concept
|
Androsterone
|
|
Concept
|
Adult
|
|
Concept
|
Angiotensin II
|
|
Concept
|
Angiotensin-Converting Enzyme Inhibitors
|
|
Concept
|
Aniline Compounds
|
|
Concept
|
Animals
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Hypoxia
|
|
Concept
|
Haplorhini
|
|
Concept
|
Age Factors
|
|
Concept
|
Aged
|
|
Concept
|
Aged, 80 and over
|
|
Concept
|
Aging
|
|
Concept
|
Anti-Inflammatory Agents
|
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
|
Concept
|
Antidepressive Agents, Tricyclic
|
|
Concept
|
Mechanistic Target of Rapamycin Complex 1
|
|
Concept
|
Antigens
|
|
Concept
|
Antihypertensive Agents
|
|
Concept
|
Aldehydes
|
|
Concept
|
Alkaloids
|
|
Concept
|
Antioxidants
|
|
Concept
|
Calcium
|
|
Concept
|
Calcium Channel Agonists
|
|
Concept
|
Acetophenones
|
|
Concept
|
Calcium Channel Blockers
|
|
Concept
|
Energy Intake
|
|
Concept
|
Alzheimer Disease
|
|
Concept
|
Acetylcholine
|
|
Concept
|
Acetylcysteine
|
|
Concept
|
Cannabinoids
|
|
Concept
|
Capillary Permeability
|
|
Concept
|
Aconitate Hydratase
|
|
Concept
|
Acridines
|
|
Concept
|
Captopril
|
|
Concept
|
Amidines
|
|
Concept
|
Actins
|
|
Concept
|
Action Potentials
|
|
Concept
|
Activities of Daily Living
|
|
Concept
|
Adaptation, Physiological
|
|
Concept
|
Aminoimidazole Carboxamide
|
|
Concept
|
African Americans
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Adenosine Diphosphate
|
|
Concept
|
Calcium-Transporting ATPases
|
|
Concept
|
Cardiotonic Agents
|
|
Concept
|
Cardiovascular Agents
|
|
Concept
|
Blood Flow Velocity
|
|
Concept
|
Blood Glucose
|
|
Concept
|
Blood Platelets
|
|
Concept
|
Blood Pressure
|
|
Concept
|
Blood Vessels
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
Body Composition
|
|
Concept
|
Body Weight
|
|
Concept
|
Cardiovascular System
|
|
Concept
|
Cardiovascular Physiological Phenomena
|
|
Concept
|
Carotid Arteries
|
|
Concept
|
Basal Metabolism
|
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
|
Concept
|
Catalase
|
|
Concept
|
Behavior, Animal
|
|
Concept
|
Bradykinin
|
|
Concept
|
Brain
|
|
Concept
|
Brain Concussion
|
|
Concept
|
Brain Edema
|
|
Concept
|
Brain Injuries
|
|
Concept
|
Brain Mapping
|
|
Concept
|
Cats
|
|
Concept
|
Cattle
|
|
Concept
|
Cecum
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
Cell Communication
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Extracts
|
|
Concept
|
Cell Line
|
|
Concept
|
Cell Movement
|
|
Concept
|
beta-Galactosidase
|
|
Concept
|
Electron Transport Complex IV
|
|
Concept
|
Cytochrome P-450 Enzyme System
|
|
Concept
|
Cytophotometry
|
|
Concept
|
Cytoskeletal Proteins
|
|
Concept
|
Betamethasone
|
|
Concept
|
C-Reactive Protein
|
|
Concept
|
Dehydroepiandrosterone
|
|
Concept
|
Biotin
|
|
Concept
|
Biotransformation
|
|
Concept
|
Dementia
|
|
Concept
|
Chromatography, Affinity
|
|
Concept
|
Chromatography, High Pressure Liquid
|
|
Concept
|
Constriction, Pathologic
|
|
Concept
|
Chronic Disease
|
|
Concept
|
Coronary Artery Disease
|
|
Concept
|
Coronary Circulation
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Deoxyguanosine
|
|
Concept
|
Circadian Rhythm
|
|
Concept
|
Citric Acid Cycle
|
|
Concept
|
Depression
|
|
Concept
|
Depressive Disorder
|
|
Concept
|
Cross-Sectional Studies
|
|
Concept
|
Crosses, Genetic
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Diabetes Mellitus, Type 1
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
Diabetic Angiopathies
|
|
Concept
|
Diabetic Retinopathy
|
|
Concept
|
Evoked Potentials, Somatosensory
|
|
Concept
|
Cognition
|
|
Concept
|
Cognition Disorders
|
|
Concept
|
Biological Evolution
|
|
Concept
|
Exercise Test
|
|
Concept
|
Exercise Therapy
|
|
Concept
|
Exploratory Behavior
|
|
Concept
|
Extracellular Matrix
|
|
Concept
|
Collagen
|
|
Concept
|
Endothelium
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Energy Metabolism
|
|
Concept
|
Community Health Services
|
|
Concept
|
Fatty Acids
|
|
Concept
|
Enoyl-CoA Hydratase
|
|
Concept
|
Fatty Acids, Unsaturated
|
|
Concept
|
Femoral Artery
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Enzyme Induction
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Ferrets
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Postural Balance
|
|
Concept
|
Fetus
|
|
Concept
|
Fibrin
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Drug Resistance
|
|
Concept
|
Fibronectins
|
|
Concept
|
Dwarfism
|
|
Concept
|
Estrogens
|
|
Concept
|
Ethidium
|
|
Concept
|
Heterocyclic Compounds, 4 or More Rings
|
|
Concept
|
Cyclic GMP
|
|
Concept
|
Guanylate Cyclase
|
|
Concept
|
Electric Conductivity
|
|
Concept
|
Hip Fractures
|
|
Concept
|
Hippocampus
|
|
Concept
|
Histamine
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
Electron Transport
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Homeostasis
|
|
Concept
|
Homocysteine
|
|
Concept
|
Health
|
|
Concept
|
Health Status
|
|
Concept
|
Heart
|
|
Concept
|
Humans
|
|
Concept
|
Encephalitis
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Heart Diseases
|
|
Concept
|
Heart Failure
|
|
Concept
|
Heat-Shock Proteins
|
|
Concept
|
Hydrazines
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Heme Oxygenase (Decyclizing)
|
|
Concept
|
Hemodynamics
|
|
Concept
|
Geriatrics
|
|
Concept
|
Gestational Age
|
|
Concept
|
Life Expectancy
|
|
Concept
|
Ligation
|
|
Concept
|
Hemoglobinometry
|
|
Concept
|
Hemorrhage
|
|
Concept
|
Gliosis
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Lipoproteins, LDL
|
|
Concept
|
Liposomes
|
|
Concept
|
Glucocorticoids
|
|
Concept
|
Gluconates
|
|
Concept
|
Glucose
|
|
Concept
|
Glucose Tolerance Test
|
|
Concept
|
Glucosephosphate Dehydrogenase
|
|
Concept
|
Liver
|
|
Concept
|
Kidney
|
|
Concept
|
Longevity
|
|
Concept
|
Longitudinal Studies
|
|
Concept
|
Luminescent Measurements
|
|
Concept
|
Glutathione
|
|
Concept
|
Glutathione Peroxidase
|
|
Concept
|
Glutathione Synthase
|
|
Concept
|
Glycerol
|
|
Concept
|
Kinetics
|
|
Concept
|
Glycolysis
|
|
Concept
|
Glycoproteins
|
|
Concept
|
Lymphokines
|
|
Concept
|
Lysophospholipids
|
|
Concept
|
Macaca mulatta
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Lameness, Animal
|
|
Concept
|
Laminin
|
|
Concept
|
Lasers
|
|
Concept
|
Mammals
|
|
Concept
|
Inflammation
|
|
Concept
|
Learning
|
|
Concept
|
Mammary Neoplasms, Experimental
|
|
Concept
|
Neuronal Plasticity
|
|
Concept
|
Neurons
|
|
Concept
|
Neuropsychological Tests
|
|
Concept
|
Insulin
|
|
Concept
|
Insulin-Like Growth Factor I
|
|
Concept
|
Nicotinamide Mononucleotide
|
|
Concept
|
Nifedipine
|
|
Concept
|
Multienzyme Complexes
|
|
Concept
|
Multiple Organ Failure
|
|
Concept
|
Muscle Contraction
|
|
Concept
|
Muscle Relaxation
|
|
Concept
|
Muscle Tonus
|
|
Concept
|
Muscle, Smooth
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
Nimodipine
|
|
Concept
|
Nitrates
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Nitriles
|
|
Concept
|
Nitrites
|
|
Concept
|
Interleukins
|
|
Concept
|
Nitroprusside
|
|
Concept
|
Interneurons
|
|
Concept
|
Intracellular Fluid
|
|
Concept
|
Myelin Sheath
|
|
Concept
|
Cardiomyopathies
|
|
Concept
|
Myocardial Infarction
|
|
Concept
|
Myocardium
|
|
Concept
|
Norepinephrine
|
|
Concept
|
NAD
|
|
Concept
|
NADH, NADPH Oxidoreductases
|
|
Concept
|
NADP
|
|
Concept
|
NADPH Dehydrogenase
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Ion Channels
|
|
Concept
|
Ionophores
|
|
Concept
|
Obesity
|
|
Concept
|
Neoplasms
|
|
Concept
|
Neovascularization, Pathologic
|
|
Concept
|
Nerve Degeneration
|
|
Concept
|
Nerve Fibers, Myelinated
|
|
Concept
|
Plant Extracts
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Nervous System Diseases
|
|
Concept
|
Platelet Aggregation
|
|
Concept
|
Platelet Aggregation Inhibitors
|
|
Concept
|
Platelet Function Tests
|
|
Concept
|
Neuroglia
|
|
Concept
|
Pneumonia, Viral
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Inbred ICR
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Mice, Obese
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Microcirculation
|
|
Concept
|
Phenanthrenes
|
|
Concept
|
Phenanthridines
|
|
Concept
|
Poly(ADP-ribose) Polymerases
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Middle Aged
|
|
Concept
|
Phenotype
|
|
Concept
|
Polyethylene Glycols
|
|
Concept
|
Mitochondria
|
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Mitochondria, Muscle
|
|
Concept
|
Models, Biological
|
|
Concept
|
Models, Neurological
|
|
Concept
|
Phosphodiesterase Inhibitors
|
|
Concept
|
Potassium Chloride
|
|
Concept
|
Potassium Cyanide
|
|
Concept
|
Monocytes
|
|
Concept
|
Phosphoproteins
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Photic Stimulation
|
|
Concept
|
Motor Activity
|
|
Concept
|
Motor Cortex
|
|
Concept
|
Predictive Value of Tests
|
|
Concept
|
Pregnancy
|
|
Concept
|
Movement Disorders
|
|
Concept
|
Physiology
|
|
Concept
|
Physiology, Comparative
|
|
Concept
|
Papillary Muscles
|
|
Concept
|
Piperidines
|
|
Concept
|
Regional Blood Flow
|
|
Concept
|
Parabiosis
|
|
Concept
|
Rejuvenation
|
|
Concept
|
Renal Circulation
|
|
Concept
|
Renin-Angiotensin System
|
|
Concept
|
Research
|
|
Concept
|
Patient Acceptance of Health Care
|
|
Concept
|
Rest
|
|
Concept
|
Resuscitation
|
|
Concept
|
Retina
|
|
Concept
|
Retinal Artery
|
|
Concept
|
Retinal Vessels
|
|
Concept
|
Reversal Learning
|
|
Concept
|
Seawater
|
|
Concept
|
Penicillamine
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Ribonucleotides
|
|
Concept
|
Pentose Phosphate Pathway
|
|
Concept
|
Peptides
|
|
Concept
|
Serotonin
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
Sex Characteristics
|
|
Concept
|
Risk Factors
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Perfusion
|
|
Concept
|
Sex Factors
|
|
Concept
|
Periodicals as Topic
|
|
Concept
|
Rodentia
|
|
Concept
|
Thromboxane A2
|
|
Concept
|
Peromyscus
|
|
Concept
|
Pulsatile Flow
|
|
Concept
|
Punctures
|
|
Concept
|
Purinones
|
|
Concept
|
Pyrazoles
|
|
Concept
|
Swimming
|
|
Concept
|
Time Factors
|
|
Concept
|
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt
|
|
Concept
|
Tissue Survival
|
|
Concept
|
Tobacco
|
|
Concept
|
Pyridines
|
|
Concept
|
Pyridones
|
|
Concept
|
Pyrrolidines
|
|
Concept
|
Pyrrolidinones
|
|
Concept
|
Quality of Life
|
|
Concept
|
Quinazolines
|
|
Concept
|
Tars
|
|
Concept
|
Quinoxalines
|
|
Concept
|
Rabbits
|
|
Concept
|
Radiation Injuries
|
|
Concept
|
Radiation Injuries, Experimental
|
|
Concept
|
Temperature
|
|
Concept
|
Teratogens
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Transfection
|
|
Concept
|
Tetradecanoylphorbol Acetate
|
|
Concept
|
Tetrazoles
|
|
Concept
|
Random Allocation
|
|
Concept
|
Rats, Inbred BN
|
|
Concept
|
Rats, Inbred F344
|
|
Concept
|
Rats, Inbred Lew
|
|
Concept
|
Rats, Inbred SHR
|
|
Concept
|
Rats, Inbred WKY
|
|
Concept
|
Biosensing Techniques
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Thiazoles
|
|
Concept
|
Thiocarbamates
|
|
Concept
|
Biomarkers
|
|
Concept
|
Exercise
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Rats, Zucker
|
|
Concept
|
Reaction Time
|
|
Concept
|
Xanthine Oxidase
|
|
Concept
|
Receptors, Immunologic
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Receptors, LDL
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Bone Density
|
|
Concept
|
Transcriptional Activation
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Nitrosation
|
|
Concept
|
Platelet Activation
|
|
Concept
|
Reference Values
|
|
Concept
|
Spine
|
|
Concept
|
Zoonoses
|
|
Concept
|
Splanchnic Circulation
|
|
Concept
|
6-Aminonicotinamide
|
|
Concept
|
8,11,14-Eicosatrienoic Acid
|
|
Concept
|
9,10-Dimethyl-1,2-benzanthracene
|
|
Concept
|
Dementia, Vascular
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Cortical Spreading Depression
|
|
Concept
|
Hominidae
|
|
Concept
|
Stem Cells
|
|
Concept
|
Eicosanoids
|
|
Concept
|
Calcium Channels
|
|
Concept
|
Potassium Channels
|
|
Concept
|
Sodium Channels
|
|
Concept
|
Lipid Peroxidation
|
|
Concept
|
Dinoprostone
|
|
Concept
|
Dinoprost
|
|
Concept
|
Cadherins
|
|
Concept
|
Stilbenes
|
|
Concept
|
Citalopram
|
|
Concept
|
Stress, Mechanical
|
|
Concept
|
Stroke Volume
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Subarachnoid Hemorrhage
|
|
Concept
|
Interleukin-10
|
|
Concept
|
Apoptosis
|
|
Concept
|
Sucrose
|
|
Concept
|
Sulfonamides
|
|
Concept
|
Superoxides
|
|
Concept
|
Superoxide Dismutase
|
|
Concept
|
Cyclooxygenase Inhibitors
|
|
Concept
|
Oxidants
|
|
Concept
|
Serotonin Uptake Inhibitors
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Cellular Senescence
|
|
Concept
|
Cell Death
|
|
Concept
|
Valsalva Maneuver
|
|
Concept
|
Vascular Diseases
|
|
Concept
|
Vascular Patency
|
|
Concept
|
Vascular Resistance
|
|
Concept
|
Vasculitis
|
|
Concept
|
Vasoconstriction
|
|
Concept
|
Vasoconstrictor Agents
|
|
Concept
|
Prefrontal Cortex
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Vasodilation
|
|
Concept
|
Vasodilator Agents
|
|
Concept
|
Vasomotor System
|
|
Concept
|
Pharmaceutical Vehicles
|
|
Concept
|
Vibrissae
|
|
Concept
|
Receptors, Thromboxane
|
|
Concept
|
Culture Media, Conditioned
|
|
Concept
|
Exercise Tolerance
|
|
Concept
|
Receptor, IGF Type 1
|
|
Concept
|
Intercellular Adhesion Molecule-1
|
|
Concept
|
Sepsis
|
|
Concept
|
Transcription Factor AP-1
|
|
Concept
|
Visual Perception
|
|
Concept
|
Glycation End Products, Advanced
|
|
Concept
|
Oxidative Stress
|
|
Concept
|
Inflammation Mediators
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Models, Immunological
|
|
Concept
|
Disease Progression
|
|
Concept
|
Muscle, Skeletal
|
|
Concept
|
Muscle Fibers, Skeletal
|
|
Concept
|
Ventricular Dysfunction, Left
|
|
Concept
|
Hyperoxia
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Chemokines
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Chemokine CCL2
|
|
Concept
|
Antigens, CD34
|
|
Concept
|
Disease Transmission, Infectious
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Whole-Body Irradiation
|
|
Concept
|
Wine
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
Insulin-Like Growth Factor Binding Proteins
|
|
Concept
|
Extracellular Matrix Proteins
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Charybdotoxin
|
|
Concept
|
Nitric Oxide Synthase
|
|
Concept
|
Vascular Cell Adhesion Molecule-1
|
|
Concept
|
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
|
|
Concept
|
Cranial Irradiation
|
|
Concept
|
Antidepressive Agents, Second-Generation
|
|
Concept
|
Excitatory Amino Acid Antagonists
|
|
Concept
|
Neuroprotective Agents
|
|
Concept
|
src-Family Kinases
|
|
Concept
|
Microscopy, Video
|
|
Concept
|
Hand Strength
|
|
Concept
|
Bridged Bicyclo Compounds, Heterocyclic
|
|
Concept
|
Tight Junctions
|
|
Concept
|
Bacteremia
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
Maze Learning
|
|
Concept
|
Peripheral Vascular Diseases
|
|
Concept
|
Drug Delivery Systems
|
|
Concept
|
Prosencephalon
|
|
Concept
|
Amyloid beta-Protein Precursor
|
|
Concept
|
Stroke
|
|
Concept
|
tert-Butylhydroperoxide
|
|
Concept
|
Sirolimus
|
|
Concept
|
Recovery of Function
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Hyperhomocysteinemia
|
|
Concept
|
Enzyme Activators
|
|
Concept
|
Lateral Ventricles
|
|
Concept
|
Caspases
|
|
Concept
|
Cerebral Amyloid Angiopathy
|
|
Concept
|
NAD(P)H Dehydrogenase (Quinone)
|
|
Concept
|
Response Elements
|
|
Concept
|
Monocrotaline
|
|
Concept
|
Pericytes
|
|
Concept
|
In Situ Nick-End Labeling
|
|
Concept
|
Intracranial Hemorrhages
|
|
Concept
|
Gene Transfer Techniques
|
|
Concept
|
Interleukin-17
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Receptors, Prostaglandin E
|
|
Concept
|
rhoA GTP-Binding Protein
|
|
Concept
|
Middle Cerebral Artery
|
|
Concept
|
Matrix Metalloproteinase 9
|
|
Concept
|
Receptors, AMPA
|
|
Concept
|
Receptors, Tumor Necrosis Factor
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
Matrix Metalloproteinases
|
|
Concept
|
Receptors, Cytoplasmic and Nuclear
|
|
Concept
|
Immunomagnetic Separation
|
|
Concept
|
Diffuse Axonal Injury
|
|
Concept
|
Isoprostanes
|
|
Concept
|
Peroxynitrous Acid
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Coronavirus Infections
|
|
Concept
|
Caloric Restriction
|
|
Concept
|
Chondroitin ABC Lyase
|
|
Concept
|
Tetraethylammonium
|
|
Concept
|
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
|
|
Concept
|
Glutathione Disulfide
|
|
Concept
|
Heparan Sulfate Proteoglycans
|
|
Concept
|
Simvastatin
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Paracrine Communication
|
|
Concept
|
Pancreas
|
|
Concept
|
Prenatal Exposure Delayed Effects
|
|
Concept
|
Genes, p16
|
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
|
Concept
|
Preventive Medicine
|
|
Concept
|
Primates
|
|
Concept
|
Endothelial Cells
|
|
Concept
|
Genomic Instability
|
|
Concept
|
Electron Transport Complex II
|
|
Concept
|
Electron Transport Complex I
|
|
Concept
|
Ribonuclease III
|
|
Concept
|
Prognosis
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Nitric Oxide Donors
|
|
Concept
|
Receptor, Muscarinic M1
|
|
Concept
|
Receptor, Cannabinoid, CB1
|
|
Concept
|
Receptor, Cannabinoid, CB2
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Prostaglandins
|
|
Concept
|
Prostaglandins H
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Kinase C
|
|
Concept
|
Proteins
|
|
Concept
|
Chondroitin Sulfate Proteoglycans
|
|
Concept
|
Proteoglycans
|
|
Concept
|
Prostaglandin H2
|
|
Concept
|
Psychomotor Disorders
|
|
Concept
|
Reactive Nitrogen Species
|
|
Concept
|
S-Nitroso-N-Acetylpenicillamine
|
|
Concept
|
Psychomotor Performance
|
|
Concept
|
Public Health
|
|
Concept
|
Potassium Channel Blockers
|
|
Concept
|
Sodium Channel Blockers
|
|
Concept
|
Pulmonary Artery
|
|
Concept
|
Shock, Septic
|
|
Concept
|
bcl-X Protein
|
|
Concept
|
Apoptosis Inducing Factor
|
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channels
|
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
|
|
Concept
|
Sleep Deprivation
|
|
Concept
|
Pituitary Adenylate Cyclase-Activating Polypeptide
|
|
Concept
|
Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide
|
|
Concept
|
Caveolin 1
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
Vitis
|
|
Concept
|
Smoke
|
|
Concept
|
Smoking
|
|
Concept
|
Mice
|
|
Concept
|
Rats
|
|
Concept
|
Genetic Pleiotropy
|
|
Concept
|
Nanoconjugates
|
|
Concept
|
Peripheral Arterial Disease
|
|
Concept
|
Societies, Scientific
|
|
Concept
|
Cyclooxygenase 1
|
|
Concept
|
Cyclooxygenase 2
|
|
Concept
|
Heme Oxygenase-1
|
|
Concept
|
Pandemics
|
|
Concept
|
Somatomedins
|
|
Concept
|
Somatosensory Cortex
|
|
Concept
|
Growth Hormone
|
|
Concept
|
Purinergic P2Y Receptor Agonists
|
|
Concept
|
Species Specificity
|
|
Concept
|
Sphingosine
|
|
Concept
|
Ankle Brachial Index
|
|
Concept
|
Stem Cell Niche
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Bone Morphogenetic Protein 2
|
|
Concept
|
Tyrosine
|
|
Concept
|
Electron Transport Complex III
|
|
Concept
|
Bone Morphogenetic Protein 4
|
|
Concept
|
Neurogenesis
|
|
Concept
|
Ultrasonography
|
|
Concept
|
United States
|
|
Concept
|
Connective Tissue Growth Factor
|
|
Concept
|
Urea
|
|
Concept
|
Spatial Memory
|
|
Concept
|
Spatial Learning
|
|
Concept
|
Purinergic P2Y Receptor Antagonists
|
|
Concept
|
Neural Stem Cells
|
|
Concept
|
White Matter
|
|
Concept
|
Gray Matter
|
|
Concept
|
Sensorimotor Cortex
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Gene Expression
|
|
Concept
|
Infusion Pumps, Implantable
|
|
Concept
|
Vascular Stiffness
|
|
Concept
|
Diet, High-Fat
|
|
Concept
|
RNA Interference
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Public Health Practice
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Lower Extremity
|
|
Concept
|
Incidence
|
|
Concept
|
Survival Rate
|
|
Concept
|
Multivariate Analysis
|
|
Concept
|
Confidence Intervals
|
|
Concept
|
Linear Models
|
|
Concept
|
Odds Ratio
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
Bone Marrow Transplantation
|
|
Concept
|
Transcriptome
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Biomedical Research
|
|
Concept
|
Walking
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Free Radical Scavengers
|
|
Concept
|
Microscopy, Fluorescence, Multiphoton
|
|
Concept
|
Leukocyte Rolling
|
|
Concept
|
Cytokines
|
|
Concept
|
Interleukin-8
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Endothelial Growth Factors
|
|
Concept
|
Amyloid beta-Peptides
|
|
Concept
|
Endothelins
|
|
Concept
|
Sirtuins
|
|
Concept
|
Aborted Fetus
|
|
Concept
|
Fura-2
|
|
Concept
|
Proto-Oncogene Proteins c-myc
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Ventricular Function, Left
|
|
Concept
|
Ventricular Function, Right
|
|
Concept
|
Atrial Function, Left
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Premature Birth
|
|
Concept
|
Ultrasonography, Doppler, Transcranial
|
|
Concept
|
Vascular Remodeling
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
|
Concept
|
Tumor Necrosis Factors
|
|
Concept
|
Microglia
|
|
Concept
|
Gap Junctions
|
|
Concept
|
Hydroxyl Radical
|
|
Concept
|
In Vitro Techniques
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Diffusion Magnetic Resonance Imaging
|
|
Concept
|
Ventricular Pressure
|
|
Concept
|
Luminescence
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
Bivalvia
|
|
Concept
|
Mercenaria
|
|
Concept
|
RANK Ligand
|
|
Concept
|
Neuropilin-1
|
|
Concept
|
DEAD-box RNA Helicases
|
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
|
Concept
|
Vascular Endothelial Growth Factor Receptor-2
|
|
Concept
|
Mechanotransduction, Cellular
|
|
Concept
|
Sarcoplasmic Reticulum Calcium-Transporting ATPases
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Proteomics
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
Tomography, Optical Coherence
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Platelet-Rich Plasma
|
|
Concept
|
Interleukin-12 Subunit p40
|
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Spectroscopy, Near-Infrared
|
|
Concept
|
Early Diagnosis
|
|
Concept
|
Microdissection
|
|
Concept
|
Vascular Endothelial Growth Factors
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Vascular Endothelial Growth Factor B
|
|
Concept
|
Staurosporine
|
|
Concept
|
Evidence-Based Medicine
|
|
Concept
|
omega-N-Methylarginine
|
|
Concept
|
NG-Nitroarginine Methyl Ester
|
|
Concept
|
Endothelin-1
|
|
Concept
|
Nitroarginine
|
|
Concept
|
Transforming Growth Factor beta1
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
Ki-67 Antigen
|
|
Concept
|
Angiopoietin-2
|
|
Concept
|
DNA Fragmentation
|
|
Concept
|
Cerebrum
|
|
Concept
|
Leukoencephalopathies
|
|
Concept
|
Protein Carbonylation
|
|
Concept
|
TRPC Cation Channels
|
|
Concept
|
TRPM Cation Channels
|
|
Concept
|
Atherosclerosis
|
|
Concept
|
Hindlimb Suspension
|
|
Concept
|
Dietary Sucrose
|
|
Concept
|
Bone Morphogenetic Proteins
|
|
Concept
|
Mole Rats
|
|
Concept
|
Neocortex
|
|
Concept
|
Intracranial Hypertension
|
|
Concept
|
Dietary Supplements
|
|
Concept
|
Cytoprotection
|
|
Concept
|
Wet Macular Degeneration
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Tight Junction Proteins
|
|
Concept
|
Pulse Wave Analysis
|
|
Concept
|
Carcinogenesis
|
|
Concept
|
Models, Animal
|
|
Concept
|
Mitochondrial Proteins
|
|
Concept
|
Collagen Type IV
|
|
Concept
|
Plaque, Amyloid
|
|
Concept
|
Amyloidogenic Proteins
|
|
Concept
|
Receptors, Prostaglandin E, EP1 Subtype
|
|
Concept
|
Receptors, Prostaglandin E, EP4 Subtype
|
|
Concept
|
Electron Transport Chain Complex Proteins
|
|
Concept
|
Receptors, Purinergic P2Y1
|
|
Concept
|
Muscle Cells
|
|
Concept
|
TOR Serine-Threonine Kinases
|
|
Concept
|
Myocytes, Cardiac
|
|
Concept
|
Myocytes, Smooth Muscle
|
|
Concept
|
Laron Syndrome
|
|
Concept
|
Culture Techniques
|
|
Concept
|
Tissue Culture Techniques
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
Benzophenanthridines
|
|
Concept
|
Caspase 3
|
|
Concept
|
Caspase 8
|
|
Concept
|
Secretory Pathway
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
ADAM Proteins
|
|
Concept
|
Smad Proteins
|
|
Concept
|
Inhibitor of Differentiation Proteins
|
|
Concept
|
SOXB1 Transcription Factors
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Kangai-1 Protein
|
|
Concept
|
Microvessels
|
|
Concept
|
Young Adult
|
|
Concept
|
Bone Morphogenetic Protein Receptors
|
|
Concept
|
Actigraphy
|
|
Concept
|
Cyclooxygenase 2 Inhibitors
|
|
Concept
|
Nitric Oxide Synthase Type II
|
|
Concept
|
Nitric Oxide Synthase Type I
|
|
Concept
|
Nitric Oxide Synthase Type III
|
|
Concept
|
Sirtuin 1
|
|
Concept
|
Sirtuin 3
|
|
Concept
|
Wnt3A Protein
|
|
Concept
|
Cognitive Dysfunction
|
|
Concept
|
Batch Cell Culture Techniques
|
|
Concept
|
Early Medical Intervention
|
|
Concept
|
Fitness Trackers
|
|
Concept
|
Microvascular Rarefaction
|
|
Concept
|
Betacoronavirus
|
|
Concept
|
Healthy Aging
|
|
Concept
|
TRPC6 Cation Channel
|
|
Concept
|
Thyroid Nuclear Factor 1
|
|
Concept
|
NADPH Oxidase 2
|
|
Concept
|
Proteostasis
|
|
Concept
|
Aorta
|
|
Concept
|
Aorta, Thoracic
|
|
Concept
|
Apamin
|
|
Concept
|
Arginine
|
|
Concept
|
Arteries
|
|
Concept
|
Arterioles
|
|
Concept
|
Arteriosclerosis
|
|
Concept
|
Arteritis
|
|
Concept
|
Ascorbic Acid
|
|
Concept
|
Aspirin
|
|
Concept
|
Astrocytes
|
|
Concept
|
Autopsy
|
|
Concept
|
Cell Separation
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Hypoxia, Brain
|
|
Concept
|
Cerebral Arteries
|
|
Concept
|
Cerebral Cortex
|
|
Concept
|
Cerebral Hemorrhage
|
|
Concept
|
Cerebral Infarction
|
|
Concept
|
Brain Ischemia
|
|
Concept
|
Cerebral Veins
|
|
Concept
|
Cerebral Ventricles
|
|
Concept
|
Cerebrovascular Circulation
|
|
Concept
|
Cerebrovascular Disorders
|
|
Concept
|
Chiroptera
|
|
Concept
|
Choroid
|
|
Concept
|
Diet
|
|
Concept
|
Dietary Fats
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Dithiothreitol
|
|
Concept
|
DNA
|
|
Concept
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DNA Damage
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Concept
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DNA Repair
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Concept
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DNA, Mitochondrial
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Concept
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Dogs
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Concept
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Fluorescent Dyes
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Concept
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Fluoxetine
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Concept
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Food Deprivation
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Concept
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Food, Formulated
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Concept
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Forecasting
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Concept
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Free Radicals
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Concept
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Gait
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Concept
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Gamma Rays
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Concept
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Glutamate-Cysteine Ligase
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Concept
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Ganglia
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Concept
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Hydroxyeicosatetraenoic Acids
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Concept
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Hyperemia
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Concept
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Hyperglycemia
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Concept
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Hypertension
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Concept
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Hypertension, Pulmonary
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Concept
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Hypertrophy
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Concept
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Hypoglycemic Agents
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Concept
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Immunoglobulin G
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Concept
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Ileum
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Concept
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Immunohistochemistry
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Concept
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Indomethacin
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Concept
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Infant, Newborn
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Concept
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Infant, Premature
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Concept
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Infant, Premature, Diseases
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Concept
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Membrane Fusion
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Concept
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Membrane Glycoproteins
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Concept
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Membrane Proteins
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Concept
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Memory
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Concept
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Memory Disorders
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Concept
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Memory, Short-Term
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Concept
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Metalloendopeptidases
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Concept
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Methionine
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Concept
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Oklahoma
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Concept
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Oligodendroglia
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Concept
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Oligopeptides
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Concept
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Onium Compounds
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Concept
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Organ Culture Techniques
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Concept
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Osteoporosis
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Concept
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Oxidation-Reduction
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Concept
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Oxidoreductases
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Concept
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Oxygen
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Concept
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Oxygen Consumption
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Concept
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Oxygen Inhalation Therapy
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Academic Article
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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
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Academic Article
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Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
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Academic Article
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Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
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Academic Article
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Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.
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Academic Article
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Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
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Academic Article
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Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
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Academic Article
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Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.
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Academic Article
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Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
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Academic Article
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Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction.
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Academic Article
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Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
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Academic Article
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Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans.
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Academic Article
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Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
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Academic Article
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Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice.
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Academic Article
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Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
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Academic Article
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Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
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Academic Article
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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
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Academic Article
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
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Academic Article
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Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
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Academic Article
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Obesity-induced cognitive impairment in older adults: a microvascular perspective.
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Academic Article
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Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
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Academic Article
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Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
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Academic Article
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Age-related decline in peripheral vascular health predicts cognitive impairment.
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Academic Article
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Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
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Academic Article
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Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
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Academic Article
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Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
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Academic Article
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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
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Academic Article
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Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
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Academic Article
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Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any?
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Academic Article
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Electrophysiological effects of homocysteine in isolated rat right ventricular papillary muscles and left atria.
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Academic Article
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Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle.
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Academic Article
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Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation.
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Academic Article
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Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?
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Academic Article
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Use of selective serotonin reuptake inhibitors and myocardial infarction.
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Academic Article
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Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.
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Academic Article
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Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.
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Academic Article
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Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
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Academic Article
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Vascular inflammation in aging.
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Academic Article
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Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
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Academic Article
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Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone.
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Academic Article
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Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
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Academic Article
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Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.
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Academic Article
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Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging.
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Academic Article
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Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase.
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Academic Article
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Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency.
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Academic Article
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Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury.
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Academic Article
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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
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Academic Article
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Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy.
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Academic Article
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Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
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Academic Article
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Comparative gerontology--from mussels to man.
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Academic Article
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Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.
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Academic Article
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Novel organotypic in vitro slice culture model for intraventricular hemorrhage of premature infants.
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Academic Article
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Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
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Academic Article
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Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
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Academic Article
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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
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Academic Article
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Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease.
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Academic Article
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Role of mitochondrial oxidative stress in hypertension.
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Academic Article
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Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.
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Academic Article
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Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
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Academic Article
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Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
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Academic Article
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Brain and cerebrovascular aging--new mechanisms and insights.
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Academic Article
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Pharmacological Strategies to Retard Cardiovascular Aging.
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Academic Article
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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
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Academic Article
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Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications.
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Academic Article
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Connective tissue growth factor (CTGF) in age-related vascular pathologies.
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Academic Article
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Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
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Academic Article
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Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
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Academic Article
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Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
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Academic Article
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Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults.
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Academic Article
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Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults.
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Academic Article
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Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation.
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Academic Article
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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice.
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Academic Article
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Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity.
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Academic Article
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Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia.
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Academic Article
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Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener.
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Academic Article
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Homocysteine reduces smooth muscle [Ca2+]i and constrictor responses of isolated arterioles.
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Academic Article
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Selected contribution: NO released to flow reduces myogenic tone of skeletal muscle arterioles by decreasing smooth muscle Ca(2+) sensitivity.
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Academic Article
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Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
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Academic Article
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Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.
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Academic Article
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Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets.
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Academic Article
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Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries.
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Academic Article
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Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.
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Academic Article
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Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.
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Academic Article
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Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
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Academic Article
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Resveratrol increases vascular oxidative stress resistance.
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Academic Article
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CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
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Academic Article
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Endothelium-derived bone morphogenic protein antagonists may counteract the proatherogenic vascular effects of bone morphogenic protein 4.
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Academic Article
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Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
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Academic Article
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Resveratrol induces mitochondrial biogenesis in endothelial cells.
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Academic Article
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Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.
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Academic Article
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Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.
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Academic Article
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Mechanisms of vascular aging: new perspectives.
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Academic Article
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Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain.
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Academic Article
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SRT1720 improves survival and healthspan of obese mice.
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Academic Article
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The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
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Academic Article
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Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).
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Academic Article
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Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.
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Academic Article
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Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
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Academic Article
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Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
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Academic Article
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Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
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Academic Article
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Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
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Academic Article
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Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
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Academic Article
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Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease.
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Academic Article
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Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
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Academic Article
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Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
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Academic Article
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Biotin-conjugated fusogenic liposomes for high-quality cell purification.
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Academic Article
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INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE.
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Academic Article
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Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
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Academic Article
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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
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Academic Article
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The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
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Academic Article
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Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease.
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Academic Article
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Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
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Academic Article
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Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
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Academic Article
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Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.
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Academic Article
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Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies.
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Academic Article
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Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?
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Academic Article
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Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
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Academic Article
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
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Academic Article
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IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
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Academic Article
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Assessment of endothelial function in leptomeningeal arterioles derived from patients with Alzheimer's disease and vascular cognitive impairment.
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Academic Article
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Glycogen synthase kinase-3ß inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A.
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Academic Article
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Mechanisms of Vascular Aging.
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Academic Article
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Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
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Academic Article
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Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats.
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Academic Article
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Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31.
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Academic Article
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Prostaglandin E2, a postulated mediator of neurovascular coupling, at low concentrations dilates whereas at higher concentrations constricts human cerebral parenchymal arterioles.
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Academic Article
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CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
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Academic Article
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Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar.
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Academic Article
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Traumatic brain injury-induced cerebral microbleeds in the elderly.
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Academic Article
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Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis.
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Academic Article
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Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role?
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Academic Article
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Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C.
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Academic Article
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Simultaneously increased TxA(2) activity in isolated arterioles and platelets of rats with hyperhomocysteinemia.
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Academic Article
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Role of endothelial [Ca2+]i in activation of eNOS in pressurized arterioles by agonists and wall shear stress.
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Academic Article
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Serotonin reuptake inhibitors fluoxetine and citalopram relax intestinal smooth muscle.
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Academic Article
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Mediation of EDHF-induced reduction of smooth muscle [Ca(2+)](i) and arteriolar dilation by K(+) channels, 5,6-EET, and gap junctions.
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Academic Article
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Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels.
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Academic Article
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Increased NO-mediated and reduced TxA2-dependent responses in skeletal muscle arterioles in pregnancy.
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Academic Article
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High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.
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Academic Article
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Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries.
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Academic Article
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Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
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Academic Article
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Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease.
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Academic Article
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Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
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Academic Article
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Altered mitochondrial energy metabolism may play a role in vascular aging.
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Academic Article
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Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts.
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Academic Article
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Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway.
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Academic Article
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Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance.
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Academic Article
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Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
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Academic Article
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Paucity of pericytes in germinal matrix vasculature of premature infants.
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Academic Article
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Oxidative stress in vascular senescence: lessons from successfully aging species.
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Academic Article
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Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.
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Academic Article
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Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
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Academic Article
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Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling.
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Academic Article
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Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
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Academic Article
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The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.
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Academic Article
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Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
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Academic Article
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Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
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Academic Article
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Consequences of intraventricular hemorrhage in a rabbit pup model.
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Academic Article
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Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
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Academic Article
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Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
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Academic Article
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Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
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Academic Article
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Mitochondria and aging in the vascular system.
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Academic Article
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Mitochondria and cardiovascular aging.
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Academic Article
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Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
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Academic Article
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Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?
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Academic Article
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Insulin-like growth factor-1 in CNS and cerebrovascular aging.
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Academic Article
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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
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Academic Article
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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
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Academic Article
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Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
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Academic Article
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Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
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Academic Article
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Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
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Academic Article
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Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease.
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Academic Article
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Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
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Academic Article
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IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
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Academic Article
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Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
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Academic Article
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Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
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Academic Article
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AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage.
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Academic Article
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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
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Academic Article
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GeroScience: understanding the interaction of processes of aging and chronic diseases.
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Cerebral microhemorrhages: mechanisms, consequences, and prevention.
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Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
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Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H2O2 and TRPV4-Dependent Activation of BKca Channels.
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Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.
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Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies.
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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
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Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions.
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Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
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Review of cardiovascular effects of fluoxetine, a selective serotonin reuptake inhibitor, compared to tricyclic antidepressants.
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Serotonin reuptake inhibitor fluoxetine decreases arteriolar myogenic tone by reducing smooth muscle [Ca2+]i.
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Xanthine oxidase-derived reactive oxygen species convert flow-induced arteriolar dilation to constriction in hyperhomocysteinemia: possible role of peroxynitrite.
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Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists.
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Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.
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Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
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Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?
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Resveratrol inhibits aggregation of platelets from high-risk cardiac patients with aspirin resistance.
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Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.
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Angiogenic inhibition reduces germinal matrix hemorrhage.
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Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.
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The aging kidney: role of endothelial oxidative stress and inflammation.
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Vascular aging in the longest-living rodent, the naked mole rat.
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Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
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Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.
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Oxidative stress and accelerated vascular aging: implications for cigarette smoking.
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Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.
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Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells.
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Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
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Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al.
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Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
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Mitochondrial protection by resveratrol.
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Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.
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Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?
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Are sirtuins viable targets for improving healthspan and lifespan?
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Intraventricular hemorrhage induces deposition of proteoglycans in premature rabbits, but their in vivo degradation with chondroitinase does not restore myelination, ventricle size and neurological recovery.
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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
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Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
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A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.
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Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart.
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IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
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Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
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Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
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IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
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Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
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IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
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IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
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Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease.
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Age-related impairment of metabovascular coupling during cortical spreading depolarizations.
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Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.
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Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
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Disruption of Interneuron Neurogenesis in Premature Newborns and Reversal with Estrogen Treatment.
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Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.
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Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
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Advances and challenges in geroscience research: An update.
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Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.
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Companion animals likely do not spread COVID-19 but may get infected themselves.
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Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease.
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Midlife Obesity Impairs Neurovascular Coupling Responses.
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Grant
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Age-related vascular cognitive impairment: role of endothelial senescence
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Cerebral microhemorrhages and gait dysfunction in aging
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Role of SIRT1 in vasoprotection
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Radiation-induced astrocyte dysfunction and cognitive decline
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Hemodynamic forces regulate BMPs in coronary arteries
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IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
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Effect of Growth Hormone on Neuropsychological Outcomes and Quality of Life of Patients with Traumatic Brain Injury: A Systematic Review.
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Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography.
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The future of healthy aging: translation of geroscience discoveries to public health practice.
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Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
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Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis.
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Grant
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Cerebromicrovascular rejuvenation by heterochronic blood exchange
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Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
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Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
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Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition.
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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
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Hypertension-induced cognitive impairment: from pathophysiology to public health.
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Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study.
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Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
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Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission.
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The Effect of Mild Traumatic Brain Injury on Cerebral Microbleeds in Aging.
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Cognitive decrement in older adults with symptomatic peripheral artery disease.
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
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Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
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Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging.
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Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
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Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
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Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
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Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies.
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Stringent public health measures during COVID-19 across ischemic stroke care systems: the potential impact of patient perceptions on health care-seeking behaviors.
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Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults.
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The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms.
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The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging.
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