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Csiszar, Anna
One or more keywords matched the following items that are connected to Csiszar, Anna
Item TypeName
Concept Animals
Concept Animals, Newborn
Concept Behavior, Animal
Concept Lameness, Animal
Concept Physical Conditioning, Animal
Concept Models, Animal
Concept Disease Models, Animal
Academic Article Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.
Academic Article Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Academic Article Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
Academic Article Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
Academic Article Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.
Academic Article Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Academic Article Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
Academic Article Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
Academic Article Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
Academic Article Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
Academic Article Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice.
Academic Article Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
Academic Article Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
Academic Article Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
Academic Article Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
Academic Article Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
Academic Article Obesity-induced cognitive impairment in older adults: a microvascular perspective.
Academic Article Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
Academic Article Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
Academic Article Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
Academic Article Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
Academic Article Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
Academic Article Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
Academic Article Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.
Academic Article Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.
Academic Article Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
Academic Article Vascular inflammation in aging.
Academic Article Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
Academic Article Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone.
Academic Article Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
Academic Article Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.
Academic Article Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging.
Academic Article Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase.
Academic Article Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury.
Academic Article Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
Academic Article Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy.
Academic Article Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
Academic Article Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.
Academic Article Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia.
Academic Article Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
Academic Article Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
Academic Article Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
Academic Article Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.
Academic Article Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
Academic Article Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
Academic Article Pharmacological Strategies to Retard Cardiovascular Aging.
Academic Article Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Academic Article Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
Academic Article Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
Academic Article Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice.
Academic Article Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
Academic Article Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.
Academic Article Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries.
Academic Article Premature death and age-related cardiac dysfunction in male eNOS-knockout mice.
Academic Article Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.
Academic Article Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
Academic Article Resveratrol increases vascular oxidative stress resistance.
Academic Article CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
Academic Article Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
Academic Article ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression.
Academic Article Resveratrol induces mitochondrial biogenesis in endothelial cells.
Academic Article Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.
Academic Article Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats.
Academic Article Mechanisms of vascular aging: new perspectives.
Academic Article Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain.
Academic Article SRT1720 improves survival and healthspan of obese mice.
Academic Article The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
Academic Article Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).
Academic Article Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.
Academic Article Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
Academic Article Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.
Academic Article Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
Academic Article Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
Academic Article Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
Academic Article Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
Academic Article Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
Academic Article Biotin-conjugated fusogenic liposomes for high-quality cell purification.
Academic Article The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
Academic Article Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Academic Article Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
Academic Article Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
Academic Article IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Academic Article Mechanisms of Vascular Aging.
Academic Article Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
Academic Article CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
Academic Article Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar.
Academic Article Cyclosporin A does not block exercise-induced cardiac hypertrophy.
Academic Article High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.
Academic Article Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
Academic Article Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease.
Academic Article Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
Academic Article Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.
Academic Article Altered mitochondrial energy metabolism may play a role in vascular aging.
Academic Article Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway.
Academic Article Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
Academic Article Paucity of pericytes in germinal matrix vasculature of premature infants.
Academic Article Oxidative stress in vascular senescence: lessons from successfully aging species.
Academic Article Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.
Academic Article Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Academic Article Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling.
Academic Article Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
Academic Article The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.
Academic Article Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
Academic Article Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
Academic Article Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
Academic Article Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
Academic Article Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.
Academic Article Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
Academic Article Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?
Academic Article Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Academic Article Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
Academic Article Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
Academic Article Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
Academic Article Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
Academic Article IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
Academic Article Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
Academic Article Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
Academic Article Cerebral microhemorrhages: mechanisms, consequences, and prevention.
Academic Article Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.
Academic Article Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
Academic Article Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
Academic Article Age-related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging.
Academic Article Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists.
Academic Article Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.
Academic Article Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
Academic Article Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?
Academic Article Angiogenic inhibition reduces germinal matrix hemorrhage.
Academic Article Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.
Academic Article The aging kidney: role of endothelial oxidative stress and inflammation.
Academic Article Vascular aging in the longest-living rodent, the naked mole rat.
Academic Article Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
Academic Article Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.
Academic Article Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
Academic Article Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al.
Academic Article Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
Academic Article Mitochondrial protection by resveratrol.
Academic Article Bone morphogenetic protein inhibition promotes neurological recovery after intraventricular hemorrhage.
Academic Article Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.
Academic Article Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?
Academic Article Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Academic Article Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
Academic Article A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.
Academic Article IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Academic Article Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
Academic Article Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
Academic Article IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
Academic Article Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
Academic Article IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Academic Article IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
Academic Article Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
Academic Article Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.
Academic Article Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
Academic Article Companion animals likely do not spread COVID-19 but may get infected themselves.
Academic Article Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease.
Academic Article Midlife Obesity Impairs Neurovascular Coupling Responses.
Grant Vasoprotection by Caloric Restriction Mimetics in Aging
Academic Article IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
Academic Article Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography.
Academic Article Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
Academic Article Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
Academic Article Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
Academic Article Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission.
Academic Article Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
Academic Article Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
Academic Article Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
Academic Article Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
Academic Article Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor.
Academic Article Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
Academic Article A role for the cystathionine-?-synthase /H2S axis in astrocyte dysfunction in the aging brain.
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