Item Type | Name |
Concept
|
Neurovascular Coupling
|
Concept
|
Intravital Microscopy
|
Concept
|
Academies and Institutes
|
Concept
|
Cognitive Aging
|
Concept
|
Kelch-Like ECH-Associated Protein 1
|
Concept
|
Receptor for Advanced Glycation End Products
|
Concept
|
Poly(ADP-ribose) Polymerase Inhibitors
|
Concept
|
ADAM17 Protein
|
Concept
|
Celecoxib
|
Concept
|
Etanercept
|
Concept
|
Serum Amyloid P-Component
|
Concept
|
Adenoviridae
|
Concept
|
Adipose Tissue
|
Concept
|
Anaerobiosis
|
Concept
|
Analysis of Variance
|
Concept
|
Administration, Oral
|
Concept
|
Adult
|
Concept
|
Angiotensin II
|
Concept
|
Angiotensin-Converting Enzyme Inhibitors
|
Concept
|
Aniline Compounds
|
Concept
|
Animals
|
Concept
|
Animals, Newborn
|
Concept
|
Hypoxia
|
Concept
|
Haplorhini
|
Concept
|
Age Factors
|
Concept
|
Aged
|
Concept
|
Aged, 80 and over
|
Concept
|
Aging
|
Concept
|
Anti-Inflammatory Agents
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
Concept
|
Antigens
|
Concept
|
Aldehydes
|
Concept
|
Alkaloids
|
Concept
|
Antioxidants
|
Concept
|
Calcium
|
Concept
|
Acetophenones
|
Concept
|
Energy Intake
|
Concept
|
Alzheimer Disease
|
Concept
|
Acetylcholine
|
Concept
|
Acetylcysteine
|
Concept
|
Cannabinoids
|
Concept
|
Capillary Permeability
|
Concept
|
Aconitate Hydratase
|
Concept
|
Acridines
|
Concept
|
Captopril
|
Concept
|
Amidines
|
Concept
|
Actins
|
Concept
|
Activities of Daily Living
|
Concept
|
Adaptation, Physiological
|
Concept
|
Carcinoma
|
Concept
|
African Americans
|
Concept
|
Cyclic AMP
|
Concept
|
Adenosine Diphosphate
|
Concept
|
Cardiovascular Agents
|
Concept
|
Blood Flow Velocity
|
Concept
|
Blood Glucose
|
Concept
|
Blood Platelets
|
Concept
|
Blood Pressure
|
Concept
|
Blood Vessels
|
Concept
|
Blood-Brain Barrier
|
Concept
|
Body Composition
|
Concept
|
Body Weight
|
Concept
|
Cardiovascular System
|
Concept
|
Cardiovascular Physiological Phenomena
|
Concept
|
Carotid Arteries
|
Concept
|
Catalase
|
Concept
|
Behavior, Animal
|
Concept
|
Brain
|
Concept
|
Brain Edema
|
Concept
|
Brain Injuries
|
Concept
|
Brain Mapping
|
Concept
|
Cats
|
Concept
|
Cell Adhesion
|
Concept
|
Cell Communication
|
Concept
|
Cell Count
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Line
|
Concept
|
Cell Movement
|
Concept
|
beta-Galactosidase
|
Concept
|
Electron Transport Complex IV
|
Concept
|
Cytochrome P-450 Enzyme System
|
Concept
|
Cytoskeletal Proteins
|
Concept
|
Betamethasone
|
Concept
|
C-Reactive Protein
|
Concept
|
Biotin
|
Concept
|
Dementia
|
Concept
|
Chromatography, High Pressure Liquid
|
Concept
|
Coronary Artery Disease
|
Concept
|
Coronary Circulation
|
Concept
|
Coronary Vessels
|
Concept
|
Deoxyguanosine
|
Concept
|
Circadian Rhythm
|
Concept
|
Citric Acid Cycle
|
Concept
|
Depression
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Crosses, Genetic
|
Concept
|
Clathrin
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Diabetes Mellitus, Experimental
|
Concept
|
Diabetes Mellitus, Type 1
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Diabetic Angiopathies
|
Concept
|
Diabetic Retinopathy
|
Concept
|
Evoked Potentials, Somatosensory
|
Concept
|
Cognition
|
Concept
|
Cognition Disorders
|
Concept
|
Biological Evolution
|
Concept
|
Exercise Test
|
Concept
|
Exercise Therapy
|
Concept
|
Physical Exertion
|
Concept
|
Exophthalmos
|
Concept
|
Exploratory Behavior
|
Concept
|
Extracellular Matrix
|
Concept
|
Cystathionine
|
Concept
|
Cystathionine beta-Synthase
|
Concept
|
Collagen
|
Concept
|
Endocytosis
|
Concept
|
Endothelium
|
Concept
|
Endothelium, Vascular
|
Concept
|
Energy Metabolism
|
Concept
|
Community Health Services
|
Concept
|
Enoyl-CoA Hydratase
|
Concept
|
Fatty Acids, Unsaturated
|
Concept
|
Femoral Artery
|
Concept
|
Enzyme Activation
|
Concept
|
Enzyme Induction
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Ferrets
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Epithelial Cells
|
Concept
|
Postural Balance
|
Concept
|
Fetus
|
Concept
|
Fibroblasts
|
Concept
|
Drug Resistance
|
Concept
|
Fibronectins
|
Concept
|
Dwarfism
|
Concept
|
Dwarfism, Pituitary
|
Concept
|
Ethidium
|
Concept
|
Heterocyclic Compounds, 4 or More Rings
|
Concept
|
Electric Conductivity
|
Concept
|
Hippocampus
|
Concept
|
Guinea Pigs
|
Concept
|
Electron Transport
|
Concept
|
Homeostasis
|
Concept
|
Health Status
|
Concept
|
Humans
|
Concept
|
Encephalitis
|
Concept
|
Gene Expression Regulation
|
Concept
|
Heart Diseases
|
Concept
|
Cardiomegaly
|
Concept
|
Heart Failure
|
Concept
|
Heart Function Tests
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Hydrazines
|
Concept
|
Genetic Vectors
|
Concept
|
Hydrogen Peroxide
|
Concept
|
Hydrogen Sulfide
|
Concept
|
Heme Oxygenase (Decyclizing)
|
Concept
|
Hemodynamics
|
Concept
|
Geriatrics
|
Concept
|
Gestational Age
|
Concept
|
Life Expectancy
|
Concept
|
Hemoglobinometry
|
Concept
|
Gliosis
|
Concept
|
Lipopolysaccharides
|
Concept
|
Lipoproteins, LDL
|
Concept
|
Liposomes
|
Concept
|
Glucocorticoids
|
Concept
|
Glucose
|
Concept
|
Glucose Tolerance Test
|
Concept
|
Liver
|
Concept
|
Liver Neoplasms
|
Concept
|
Kidney
|
Concept
|
Longevity
|
Concept
|
Longitudinal Studies
|
Concept
|
Luminescent Measurements
|
Concept
|
Glutathione
|
Concept
|
Glutathione Peroxidase
|
Concept
|
Glutathione Synthase
|
Concept
|
Glycerol
|
Concept
|
Lung
|
Concept
|
Lymphokines
|
Concept
|
Lysophospholipids
|
Concept
|
Protein-Lysine 6-Oxidase
|
Concept
|
Macaca mulatta
|
Concept
|
Magnetic Resonance Imaging
|
Concept
|
Lameness, Animal
|
Concept
|
Laminin
|
Concept
|
Lasers
|
Concept
|
Inflammation
|
Concept
|
Learning
|
Concept
|
Mammary Neoplasms, Experimental
|
Concept
|
Neuronal Plasticity
|
Concept
|
Neurons
|
Concept
|
Neuropsychological Tests
|
Concept
|
Neurosciences
|
Concept
|
Insulin
|
Concept
|
Insulin-Like Growth Factor I
|
Concept
|
Nicotinamide Mononucleotide
|
Concept
|
Multienzyme Complexes
|
Concept
|
Multiple Organ Failure
|
Concept
|
Muscle Contraction
|
Concept
|
Muscle, Smooth
|
Concept
|
Muscle, Smooth, Vascular
|
Concept
|
Nimodipine
|
Concept
|
Nitrates
|
Concept
|
Nitric Oxide
|
Concept
|
Nitrites
|
Concept
|
Interferons
|
Concept
|
Interleukins
|
Concept
|
Interneurons
|
Concept
|
Intestinal Mucosa
|
Concept
|
Myelin Sheath
|
Concept
|
Cardiomyopathies
|
Concept
|
Myocardium
|
Concept
|
Norepinephrine
|
Concept
|
NAD
|
Concept
|
NADH, NADPH Oxidoreductases
|
Concept
|
NADPH Dehydrogenase
|
Concept
|
Nuclear Proteins
|
Concept
|
Obesity
|
Concept
|
Neoplasm Proteins
|
Concept
|
Neoplasms
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Nerve Degeneration
|
Concept
|
Nerve Tissue Proteins
|
Concept
|
Platelet Aggregation
|
Concept
|
Platelet Aggregation Inhibitors
|
Concept
|
Platelet Function Tests
|
Concept
|
Neuroglia
|
Concept
|
Pneumonia, Viral
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Inbred ICR
|
Concept
|
Mice, Inbred Strains
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Mice, Obese
|
Concept
|
Mice, Transgenic
|
Concept
|
Microcirculation
|
Concept
|
Phenanthrenes
|
Concept
|
Phenanthridines
|
Concept
|
Poly(ADP-ribose) Polymerases
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Middle Aged
|
Concept
|
Phenotype
|
Concept
|
Polyethylene Glycols
|
Concept
|
Mitochondria
|
Concept
|
Mitochondria, Heart
|
Concept
|
Mitochondria, Muscle
|
Concept
|
Models, Biological
|
Concept
|
Potassium Cyanide
|
Concept
|
Monocytes
|
Concept
|
Phosphoproteins
|
Concept
|
Phosphorylation
|
Concept
|
Photic Stimulation
|
Concept
|
Motion Pictures
|
Concept
|
Motor Activity
|
Concept
|
Motor Cortex
|
Concept
|
Physical Conditioning, Animal
|
Concept
|
Predictive Value of Tests
|
Concept
|
Pregnancy
|
Concept
|
Pregnancy Trimester, Third
|
Concept
|
Piperidines
|
Concept
|
Regional Blood Flow
|
Concept
|
Parabiosis
|
Concept
|
Rejuvenation
|
Concept
|
Renal Circulation
|
Concept
|
Renin-Angiotensin System
|
Concept
|
Research
|
Concept
|
Rest
|
Concept
|
Resuscitation
|
Concept
|
Retina
|
Concept
|
Retinal Artery
|
Concept
|
Retinal Vessels
|
Concept
|
Reversal Learning
|
Concept
|
Seawater
|
Concept
|
Penicillamine
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Peptides
|
Concept
|
Severity of Illness Index
|
Concept
|
Sex Characteristics
|
Concept
|
Risk Factors
|
Concept
|
RNA, Messenger
|
Concept
|
Sex Factors
|
Concept
|
Rodentia
|
Concept
|
Peromyscus
|
Concept
|
Pulsatile Flow
|
Concept
|
Pyrazoles
|
Concept
|
Swimming
|
Concept
|
Time Factors
|
Concept
|
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt
|
Concept
|
Tissue Distribution
|
Concept
|
Tissue Survival
|
Concept
|
Tobacco
|
Concept
|
Pyrrolidines
|
Concept
|
Quality of Life
|
Concept
|
Quinazolines
|
Concept
|
Tars
|
Concept
|
Rabbits
|
Concept
|
Radiation Injuries
|
Concept
|
Radiation Injuries, Experimental
|
Concept
|
Temperature
|
Concept
|
Transcription Factors
|
Concept
|
Transcription, Genetic
|
Concept
|
Transfection
|
Concept
|
Random Allocation
|
Concept
|
Genes, ras
|
Concept
|
Rats, Inbred BN
|
Concept
|
Rats, Inbred F344
|
Concept
|
Rats, Inbred Lew
|
Concept
|
Rats, Inbred SHR
|
Concept
|
Rats, Inbred WKY
|
Concept
|
Biosensing Techniques
|
Concept
|
Signal Transduction
|
Concept
|
Thiocarbamates
|
Concept
|
Biomarkers
|
Concept
|
Exercise
|
Concept
|
Rats, Mutant Strains
|
Concept
|
Reaction Time
|
Concept
|
Xanthine Oxidase
|
Concept
|
Receptors, Immunologic
|
Concept
|
Receptor, Insulin
|
Concept
|
Recombinant Proteins
|
Concept
|
Bone Density
|
Concept
|
Transcriptional Activation
|
Concept
|
Down-Regulation
|
Concept
|
Nitrosation
|
Concept
|
Reference Values
|
Concept
|
Spine
|
Concept
|
Zoonoses
|
Concept
|
Splanchnic Circulation
|
Concept
|
9,10-Dimethyl-1,2-benzanthracene
|
Concept
|
Dementia, Vascular
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Hominidae
|
Concept
|
Stem Cells
|
Concept
|
Eicosanoids
|
Concept
|
Potassium Channels
|
Concept
|
Dinoprostone
|
Concept
|
Cadherins
|
Concept
|
Stilbenes
|
Concept
|
Stress, Mechanical
|
Concept
|
Stroke Volume
|
Concept
|
Cohort Studies
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Rats, Wistar
|
Concept
|
Interleukin-10
|
Concept
|
Apoptosis
|
Concept
|
Paclitaxel
|
Concept
|
Sucrose
|
Concept
|
Sulfonamides
|
Concept
|
Superoxides
|
Concept
|
Superoxide Dismutase
|
Concept
|
Cyclooxygenase Inhibitors
|
Concept
|
Oxidants
|
Concept
|
Hypertrophy, Left Ventricular
|
Concept
|
Reactive Oxygen Species
|
Concept
|
Treatment Outcome
|
Concept
|
Cellular Senescence
|
Concept
|
Cell Death
|
Concept
|
Valsalva Maneuver
|
Concept
|
Vascular Diseases
|
Concept
|
Vascular Patency
|
Concept
|
Vascular Resistance
|
Concept
|
Vasculitis
|
Concept
|
Vasoconstriction
|
Concept
|
Vasoconstrictor Agents
|
Concept
|
Prefrontal Cortex
|
Concept
|
Practice Guidelines as Topic
|
Concept
|
Sequence Analysis, RNA
|
Concept
|
Vasodilation
|
Concept
|
Vasodilator Agents
|
Concept
|
Vasomotor System
|
Concept
|
Pharmaceutical Vehicles
|
Concept
|
Receptors, Interferon
|
Concept
|
Vibrissae
|
Concept
|
Receptors, Platelet-Derived Growth Factor
|
Concept
|
Culture Media, Conditioned
|
Concept
|
Exercise Tolerance
|
Concept
|
Receptor, IGF Type 1
|
Concept
|
Intercellular Adhesion Molecule-1
|
Concept
|
Transcription Factor AP-1
|
Concept
|
Visual Perception
|
Concept
|
Glycation End Products, Advanced
|
Concept
|
Oxidative Stress
|
Concept
|
Inflammation Mediators
|
Concept
|
Homeodomain Proteins
|
Concept
|
Models, Immunological
|
Concept
|
Disease Progression
|
Concept
|
Muscle, Skeletal
|
Concept
|
Ventricular Dysfunction, Left
|
Concept
|
Hyperoxia
|
Concept
|
Gene Expression Regulation, Developmental
|
Concept
|
Neovascularization, Physiologic
|
Concept
|
Chemokines
|
Concept
|
Cell Culture Techniques
|
Concept
|
Chemokine CCL2
|
Concept
|
Antigens, CD34
|
Concept
|
Disease Transmission, Infectious
|
Concept
|
Risk Assessment
|
Concept
|
Whole-Body Irradiation
|
Concept
|
Microscopy, Confocal
|
Concept
|
Insulin-Like Growth Factor Binding Proteins
|
Concept
|
Extracellular Matrix Proteins
|
Concept
|
NF-kappa B
|
Concept
|
Charybdotoxin
|
Concept
|
Nitric Oxide Synthase
|
Concept
|
Vascular Cell Adhesion Molecule-1
|
Concept
|
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
|
Concept
|
Cranial Irradiation
|
Concept
|
Neuroprotective Agents
|
Concept
|
Hand Strength
|
Concept
|
Bridged Bicyclo Compounds, Heterocyclic
|
Concept
|
Bacteremia
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
Concept
|
Maze Learning
|
Concept
|
Peripheral Vascular Diseases
|
Concept
|
Mice, SCID
|
Concept
|
Amyloid beta-Protein Precursor
|
Concept
|
Stroke
|
Concept
|
tert-Butylhydroperoxide
|
Concept
|
Recovery of Function
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Hyperhomocysteinemia
|
Concept
|
Cyclosporine
|
Concept
|
Enzyme Activators
|
Concept
|
Lateral Ventricles
|
Concept
|
Caspases
|
Concept
|
Cerebral Amyloid Angiopathy
|
Concept
|
NAD(P)H Dehydrogenase (Quinone)
|
Concept
|
Carotid-Cavernous Sinus Fistula
|
Concept
|
Response Elements
|
Concept
|
Monocrotaline
|
Concept
|
Pericytes
|
Concept
|
In Situ Nick-End Labeling
|
Concept
|
Intracranial Hemorrhages
|
Concept
|
Gene Transfer Techniques
|
Concept
|
Interleukin-17
|
Concept
|
DNA, Complementary
|
Concept
|
Receptors, Prostaglandin E
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
Middle Cerebral Artery
|
Concept
|
Matrix Metalloproteinase 9
|
Concept
|
Receptors, Tumor Necrosis Factor
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
Matrix Metalloproteinases
|
Concept
|
Immunomagnetic Separation
|
Concept
|
Isoprostanes
|
Concept
|
Peroxynitrous Acid
|
Concept
|
Mice, Knockout
|
Concept
|
Coronavirus Infections
|
Concept
|
Neurodegenerative Diseases
|
Concept
|
Caloric Restriction
|
Concept
|
Heparan Sulfate Proteoglycans
|
Concept
|
Simvastatin
|
Concept
|
Paracrine Communication
|
Concept
|
Pancreas
|
Concept
|
Prenatal Exposure Delayed Effects
|
Concept
|
Genes, p16
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
Preventive Medicine
|
Concept
|
Primates
|
Concept
|
Probability
|
Concept
|
Endothelial Cells
|
Concept
|
Genomic Instability
|
Concept
|
Ribonuclease III
|
Concept
|
Prognosis
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Calcium Signaling
|
Concept
|
Nitric Oxide Donors
|
Concept
|
Receptor, Muscarinic M1
|
Concept
|
Receptor, Cannabinoid, CB1
|
Concept
|
Receptor, Cannabinoid, CB2
|
Concept
|
Prospective Studies
|
Concept
|
Epigenesis, Genetic
|
Concept
|
Metabolic Syndrome
|
Concept
|
Protein Binding
|
Concept
|
Protein Kinase C
|
Concept
|
Proteins
|
Concept
|
Proteoglycans
|
Concept
|
Reactive Nitrogen Species
|
Concept
|
S-Nitroso-N-Acetylpenicillamine
|
Concept
|
Psychomotor Performance
|
Concept
|
Public Health
|
Concept
|
Potassium Channel Blockers
|
Concept
|
Pulmonary Artery
|
Concept
|
Shock, Septic
|
Concept
|
bcl-X Protein
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channels
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
|
Concept
|
beta Catenin
|
Concept
|
Sleep Deprivation
|
Concept
|
Pituitary Adenylate Cyclase-Activating Polypeptide
|
Concept
|
Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide
|
Concept
|
Caveolin 1
|
Concept
|
NF-E2-Related Factor 2
|
Concept
|
Smoke
|
Concept
|
Smoking
|
Concept
|
Mobility Limitation
|
Concept
|
Mice
|
Concept
|
Rats
|
Concept
|
Genetic Pleiotropy
|
Concept
|
Nanoconjugates
|
Concept
|
Peripheral Arterial Disease
|
Concept
|
Cyclooxygenase 1
|
Concept
|
Cyclooxygenase 2
|
Concept
|
Heme Oxygenase-1
|
Concept
|
Pandemics
|
Concept
|
Somatomedins
|
Concept
|
Somatosensory Cortex
|
Concept
|
Growth Hormone
|
Concept
|
Purinergic P2Y Receptor Agonists
|
Concept
|
Species Specificity
|
Concept
|
Sphingosine
|
Concept
|
Observational Studies as Topic
|
Concept
|
Ankle Brachial Index
|
Concept
|
Stem Cell Niche
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Bone Morphogenetic Protein 2
|
Concept
|
Tyrosine
|
Concept
|
Bone Morphogenetic Protein 4
|
Concept
|
Neurogenesis
|
Concept
|
Ultrasonography
|
Concept
|
United States
|
Concept
|
Connective Tissue Growth Factor
|
Concept
|
Spatial Memory
|
Concept
|
Spatial Learning
|
Concept
|
Purinergic P2Y Receptor Antagonists
|
Concept
|
Neural Stem Cells
|
Concept
|
White Matter
|
Concept
|
Gray Matter
|
Concept
|
Interleukin-6
|
Concept
|
Up-Regulation
|
Concept
|
Gene Expression
|
Concept
|
Infusion Pumps, Implantable
|
Concept
|
Vascular Stiffness
|
Concept
|
Diet, High-Fat
|
Concept
|
GABAergic Neurons
|
Concept
|
Cerebral Small Vessel Diseases
|
Concept
|
RNA Interference
|
Concept
|
Gene Expression Regulation, Enzymologic
|
Concept
|
RNA, Small Interfering
|
Concept
|
Lower Extremity
|
Concept
|
Incidence
|
Concept
|
Survival Rate
|
Concept
|
Multivariate Analysis
|
Concept
|
Confidence Intervals
|
Concept
|
Linear Models
|
Concept
|
Odds Ratio
|
Concept
|
Case-Control Studies
|
Concept
|
Bone Marrow Transplantation
|
Concept
|
Transcriptome
|
Concept
|
Tetraspanins
|
Concept
|
MicroRNAs
|
Concept
|
Walking
|
Concept
|
Free Radical Scavengers
|
Concept
|
Microscopy, Fluorescence, Multiphoton
|
Concept
|
Leukocyte Rolling
|
Concept
|
Cytokines
|
Concept
|
Interleukin-8
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Endothelial Growth Factors
|
Concept
|
Amyloid beta-Peptides
|
Concept
|
Endothelins
|
Concept
|
Sirtuins
|
Concept
|
Aborted Fetus
|
Concept
|
Fetal Development
|
Concept
|
Fura-2
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Premature Birth
|
Concept
|
Ultrasonography, Doppler, Transcranial
|
Concept
|
Vascular Remodeling
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
Concept
|
Tumor Necrosis Factors
|
Concept
|
Microglia
|
Concept
|
Gap Junctions
|
Concept
|
Hydroxyl Radical
|
Concept
|
In Vitro Techniques
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Cell Proliferation
|
Concept
|
Luminescence
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Bivalvia
|
Concept
|
Mercenaria
|
Concept
|
RANK Ligand
|
Concept
|
Neuropilin-1
|
Concept
|
DEAD-box RNA Helicases
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
Concept
|
Vascular Endothelial Growth Factor Receptor-2
|
Concept
|
Mechanotransduction, Cellular
|
Concept
|
Interleukin-1beta
|
Concept
|
Proteomics
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
Concept
|
Tomography, Optical Coherence
|
Concept
|
Genes, Reporter
|
Concept
|
Platelet-Rich Plasma
|
Concept
|
Interleukin-12 Subunit p40
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
Concept
|
NADPH Oxidases
|
Concept
|
Spectroscopy, Near-Infrared
|
Concept
|
Early Diagnosis
|
Concept
|
Microdissection
|
Concept
|
Vascular Endothelial Growth Factors
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Vascular Endothelial Growth Factor B
|
Concept
|
Staurosporine
|
Concept
|
Evidence-Based Medicine
|
Concept
|
omega-N-Methylarginine
|
Concept
|
NG-Nitroarginine Methyl Ester
|
Concept
|
Endothelin-1
|
Concept
|
Transforming Growth Factor beta1
|
Concept
|
Amyloid Precursor Protein Secretases
|
Concept
|
Human Growth Hormone
|
Concept
|
Angiopoietin-2
|
Concept
|
DNA Fragmentation
|
Concept
|
Cerebrum
|
Concept
|
Leukoencephalopathies
|
Concept
|
Protein Carbonylation
|
Concept
|
TRPC Cation Channels
|
Concept
|
TRPM Cation Channels
|
Concept
|
Atherosclerosis
|
Concept
|
Hindlimb Suspension
|
Concept
|
Dietary Sucrose
|
Concept
|
Bone Morphogenetic Proteins
|
Concept
|
Mole Rats
|
Concept
|
Neocortex
|
Concept
|
Dietary Supplements
|
Concept
|
Cytoprotection
|
Concept
|
Wet Macular Degeneration
|
Concept
|
STAT3 Transcription Factor
|
Concept
|
Mice, 129 Strain
|
Concept
|
Gene Expression Profiling
|
Concept
|
Mitogen-Activated Protein Kinases
|
Concept
|
Pulse Wave Analysis
|
Concept
|
Carcinogenesis
|
Concept
|
Hepatocytes
|
Concept
|
Models, Animal
|
Concept
|
Mitochondrial Proteins
|
Concept
|
Collagen Type IV
|
Concept
|
Plaque, Amyloid
|
Concept
|
Amyloidogenic Proteins
|
Concept
|
Receptors, Prostaglandin E, EP1 Subtype
|
Concept
|
Electron Transport Chain Complex Proteins
|
Concept
|
Receptors, Purinergic P2Y1
|
Concept
|
Muscle Cells
|
Concept
|
Myocytes, Cardiac
|
Concept
|
Myocytes, Smooth Muscle
|
Concept
|
Laron Syndrome
|
Concept
|
Culture Techniques
|
Concept
|
Tissue Culture Techniques
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
Benzophenanthridines
|
Concept
|
Caspase 3
|
Concept
|
Caspase 8
|
Concept
|
Secretory Pathway
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
ADAM Proteins
|
Concept
|
Smad Proteins
|
Concept
|
Inhibitor of Differentiation Proteins
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Kangai-1 Protein
|
Concept
|
Microvessels
|
Concept
|
Young Adult
|
Concept
|
Bone Morphogenetic Protein Receptors
|
Concept
|
Actigraphy
|
Concept
|
Cyclooxygenase 2 Inhibitors
|
Concept
|
Nitric Oxide Synthase Type II
|
Concept
|
Nitric Oxide Synthase Type I
|
Concept
|
Nitric Oxide Synthase Type III
|
Concept
|
Executive Function
|
Concept
|
Sirtuin 1
|
Concept
|
Cognitive Dysfunction
|
Concept
|
Batch Cell Culture Techniques
|
Concept
|
Early Medical Intervention
|
Concept
|
Fitness Trackers
|
Concept
|
Microvascular Rarefaction
|
Concept
|
Betacoronavirus
|
Concept
|
TRPC6 Cation Channel
|
Concept
|
Thyroid Nuclear Factor 1
|
Concept
|
NADPH Oxidase 2
|
Concept
|
Proteostasis
|
Concept
|
Aorta
|
Concept
|
Aorta, Thoracic
|
Concept
|
Apamin
|
Concept
|
Arginine
|
Concept
|
Arteries
|
Concept
|
Arterioles
|
Concept
|
Arteriosclerosis
|
Concept
|
Arteritis
|
Concept
|
Ascorbic Acid
|
Concept
|
Aspirin
|
Concept
|
Astrocytes
|
Concept
|
Autophagy
|
Concept
|
Autopsy
|
Concept
|
Cell Separation
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Cells, Cultured
|
Concept
|
Central Nervous System
|
Concept
|
Cerebral Arteries
|
Concept
|
Cerebral Cortex
|
Concept
|
Cerebral Hemorrhage
|
Concept
|
Cerebral Infarction
|
Concept
|
Brain Ischemia
|
Concept
|
Cerebral Veins
|
Concept
|
Cerebral Ventricles
|
Concept
|
Cerebrovascular Circulation
|
Concept
|
Cerebrovascular Disorders
|
Concept
|
Chiroptera
|
Concept
|
Choroid
|
Concept
|
Diagnosis, Differential
|
Concept
|
Diet
|
Concept
|
Dietary Fats
|
Concept
|
Disease Models, Animal
|
Concept
|
DNA
|
Concept
|
DNA Damage
|
Concept
|
DNA Repair
|
Concept
|
DNA, Mitochondrial
|
Concept
|
Dogs
|
Concept
|
Fluorescent Dyes
|
Concept
|
Food Deprivation
|
Concept
|
Food, Formulated
|
Concept
|
Forecasting
|
Concept
|
Free Radicals
|
Concept
|
Gait
|
Concept
|
Gamma Rays
|
Concept
|
Glutamate-Cysteine Ligase
|
Concept
|
Hydroxyeicosatetraenoic Acids
|
Concept
|
Hyperemia
|
Concept
|
Hyperglycemia
|
Concept
|
Hypertension
|
Concept
|
Hypertension, Pulmonary
|
Concept
|
Hypoglycemic Agents
|
Concept
|
Immunoglobulin G
|
Concept
|
Immunohistochemistry
|
Concept
|
Indomethacin
|
Concept
|
Infant, Newborn
|
Concept
|
Infant, Premature
|
Concept
|
Median Eminence
|
Concept
|
Membrane Fusion
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Membrane Proteins
|
Concept
|
Memory
|
Concept
|
Memory Disorders
|
Concept
|
Memory, Short-Term
|
Concept
|
Mesoderm
|
Concept
|
Metalloendopeptidases
|
Concept
|
Methionine
|
Concept
|
Oklahoma
|
Concept
|
Onium Compounds
|
Concept
|
Organ Culture Techniques
|
Concept
|
Osteoporosis
|
Concept
|
Oxidation-Reduction
|
Concept
|
Oxidoreductases
|
Concept
|
Oxygen
|
Concept
|
Oxygen Consumption
|
Concept
|
Oxygen Inhalation Therapy
|
Academic Article
|
Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.
|
Academic Article
|
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
|
Academic Article
|
Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
|
Academic Article
|
Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
|
Academic Article
|
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.
|
Academic Article
|
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
|
Academic Article
|
Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
|
Academic Article
|
Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.
|
Academic Article
|
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
|
Academic Article
|
Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction.
|
Academic Article
|
Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
|
Academic Article
|
Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans.
|
Academic Article
|
Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
|
Academic Article
|
Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice.
|
Academic Article
|
Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
|
Academic Article
|
Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
|
Academic Article
|
Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
|
Academic Article
|
Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
|
Academic Article
|
Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
|
Academic Article
|
Obesity-induced cognitive impairment in older adults: a microvascular perspective.
|
Academic Article
|
Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
|
Academic Article
|
Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
|
Academic Article
|
Age-related decline in peripheral vascular health predicts cognitive impairment.
|
Academic Article
|
Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
|
Academic Article
|
Lysyl oxidases as driving forces behind age-related macrovascular rigidity.
|
Academic Article
|
Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|
Academic Article
|
Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
|
Academic Article
|
Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
|
Academic Article
|
Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
|
Academic Article
|
Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?
|
Academic Article
|
Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.
|
Academic Article
|
Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.
|
Academic Article
|
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
|
Academic Article
|
Vascular inflammation in aging.
|
Academic Article
|
Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice.
|
Academic Article
|
Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone.
|
Academic Article
|
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
|
Academic Article
|
Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.
|
Academic Article
|
Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging.
|
Academic Article
|
Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase.
|
Academic Article
|
Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency.
|
Academic Article
|
Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury.
|
Academic Article
|
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
|
Academic Article
|
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy.
|
Academic Article
|
Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
|
Academic Article
|
Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.
|
Academic Article
|
Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia.
|
Academic Article
|
Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
|
Academic Article
|
Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
|
Academic Article
|
Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
|
Academic Article
|
Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease.
|
Academic Article
|
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.
|
Academic Article
|
Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
|
Academic Article
|
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
|
Academic Article
|
Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairment.
|
Academic Article
|
Pharmacological Strategies to Retard Cardiovascular Aging.
|
Academic Article
|
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
|
Academic Article
|
Connective tissue growth factor (CTGF) in age-related vascular pathologies.
|
Academic Article
|
Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
|
Academic Article
|
Endothelial dysfunction and angiogenesis impairment in the ageing vasculature.
|
Academic Article
|
Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults.
|
Academic Article
|
Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults.
|
Academic Article
|
Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation.
|
Academic Article
|
Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice.
|
Academic Article
|
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
|
Academic Article
|
Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.
|
Academic Article
|
Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets.
|
Academic Article
|
Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries.
|
Academic Article
|
Premature death and age-related cardiac dysfunction in male eNOS-knockout mice.
|
Academic Article
|
[Exophthalmos--case report].
|
Academic Article
|
Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.
|
Academic Article
|
Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.
|
Academic Article
|
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
|
Academic Article
|
Resveratrol increases vascular oxidative stress resistance.
|
Academic Article
|
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
|
Academic Article
|
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
|
Academic Article
|
ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression.
|
Academic Article
|
Resveratrol induces mitochondrial biogenesis in endothelial cells.
|
Academic Article
|
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.
|
Academic Article
|
Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats.
|
Academic Article
|
Mechanisms of vascular aging: new perspectives.
|
Academic Article
|
Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain.
|
Academic Article
|
SRT1720 improves survival and healthspan of obese mice.
|
Academic Article
|
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.
|
Academic Article
|
Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).
|
Academic Article
|
Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.
|
Academic Article
|
Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
|
Academic Article
|
Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.
|
Academic Article
|
Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
|
Academic Article
|
Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
|
Academic Article
|
Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
|
Academic Article
|
Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease.
|
Academic Article
|
Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
|
Academic Article
|
Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
|
Academic Article
|
Biotin-conjugated fusogenic liposomes for high-quality cell purification.
|
Academic Article
|
INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE.
|
Academic Article
|
Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
|
Academic Article
|
The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
|
Academic Article
|
Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
|
Academic Article
|
Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
|
Academic Article
|
Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.
|
Academic Article
|
Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
|
Academic Article
|
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
|
Academic Article
|
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
|
Academic Article
|
Mechanisms of Vascular Aging.
|
Academic Article
|
Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
|
Academic Article
|
CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
|
Academic Article
|
Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar.
|
Academic Article
|
Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis.
|
Academic Article
|
Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role?
|
Academic Article
|
Cyclosporin A does not block exercise-induced cardiac hypertrophy.
|
Academic Article
|
High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.
|
Academic Article
|
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
|
Academic Article
|
Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease.
|
Academic Article
|
Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure.
|
Academic Article
|
Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.
|
Academic Article
|
Altered mitochondrial energy metabolism may play a role in vascular aging.
|
Academic Article
|
Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway.
|
Academic Article
|
Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance.
|
Academic Article
|
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
|
Academic Article
|
Paucity of pericytes in germinal matrix vasculature of premature infants.
|
Academic Article
|
Oxidative stress in vascular senescence: lessons from successfully aging species.
|
Academic Article
|
Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.
|
Academic Article
|
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
|
Academic Article
|
Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling.
|
Academic Article
|
Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
|
Academic Article
|
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.
|
Academic Article
|
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
|
Academic Article
|
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
|
Academic Article
|
Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
|
Academic Article
|
Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
|
Academic Article
|
Mitochondria and aging in the vascular system.
|
Academic Article
|
Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.
|
Academic Article
|
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.
|
Academic Article
|
Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
|
Academic Article
|
Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?
|
Academic Article
|
Insulin-like growth factor-1 in CNS and cerebrovascular aging.
|
Academic Article
|
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
|
Academic Article
|
Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
|
Academic Article
|
Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
|
Academic Article
|
Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.
|
Academic Article
|
Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
|
Academic Article
|
Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease.
|
Academic Article
|
Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
|
Academic Article
|
Extended Production of Cortical Interneurons into the Third Trimester of Human Gestation.
|
Academic Article
|
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
|
Academic Article
|
Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
|
Academic Article
|
Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
|
Academic Article
|
Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
|
Academic Article
|
Cerebral microhemorrhages: mechanisms, consequences, and prevention.
|
Academic Article
|
Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
|
Academic Article
|
Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.
|
Academic Article
|
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
|
Academic Article
|
Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions.
|
Academic Article
|
Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
|
Academic Article
|
Age-related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging.
|
Academic Article
|
Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists.
|
Academic Article
|
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.
|
Academic Article
|
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.
|
Academic Article
|
Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?
|
Academic Article
|
Resveratrol inhibits aggregation of platelets from high-risk cardiac patients with aspirin resistance.
|
Academic Article
|
Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.
|
Academic Article
|
Angiogenic inhibition reduces germinal matrix hemorrhage.
|
Academic Article
|
Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.
|
Academic Article
|
The aging kidney: role of endothelial oxidative stress and inflammation.
|
Academic Article
|
Vascular aging in the longest-living rodent, the naked mole rat.
|
Academic Article
|
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.
|
Academic Article
|
Oxidative stress and accelerated vascular aging: implications for cigarette smoking.
|
Academic Article
|
Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.
|
Academic Article
|
Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells.
|
Academic Article
|
Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity.
|
Academic Article
|
Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al.
|
Academic Article
|
Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
|
Academic Article
|
Mitochondrial protection by resveratrol.
|
Academic Article
|
Bone morphogenetic protein inhibition promotes neurological recovery after intraventricular hemorrhage.
|
Academic Article
|
Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.
|
Academic Article
|
Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?
|
Academic Article
|
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
|
Academic Article
|
Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
|
Academic Article
|
A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.
|
Academic Article
|
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
|
Academic Article
|
Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
|
Academic Article
|
Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
|
Academic Article
|
IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
|
Academic Article
|
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
|
Academic Article
|
IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
|
Academic Article
|
IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
|
Academic Article
|
Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease.
|
Academic Article
|
Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.
|
Academic Article
|
Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.
|
Academic Article
|
Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.
|
Academic Article
|
Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
|
Academic Article
|
Advances and challenges in geroscience research: An update.
|
Academic Article
|
Companion animals likely do not spread COVID-19 but may get infected themselves.
|
Academic Article
|
Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease.
|
Academic Article
|
Midlife Obesity Impairs Neurovascular Coupling Responses.
|
Grant
|
Vasoprotection by Caloric Restriction Mimetics in Aging
|
Grant
|
Effects of Radiation on Brain Microvasculature and Cognition
|
Grant
|
Age-related vascular cognitive impairment: role of endothelial senescence
|
Grant
|
Microvascular mechanisms of neuroinflammation: role of Nrf2
|
Grant
|
Chemotherapy-induced vascular cognitive impairment: role of endothelial senescence
|
Academic Article
|
IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
|
Academic Article
|
Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography.
|
Academic Article
|
Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
|
Grant
|
Cerebromicrovascular rejuvenation by heterochronic blood exchange
|
Academic Article
|
Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
|
Academic Article
|
Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
|
Academic Article
|
Temporary opening of the blood-brain barrier with the nitrone compound OKN-007.
|
Academic Article
|
Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition.
|
Academic Article
|
Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
|
Academic Article
|
Hypertension-induced cognitive impairment: from pathophysiology to public health.
|
Academic Article
|
Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study.
|
Academic Article
|
Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
|
Academic Article
|
Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission.
|
Academic Article
|
Cognitive decrement in older adults with symptomatic peripheral artery disease.
|
Academic Article
|
Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
|
Academic Article
|
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
|
Academic Article
|
Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging.
|
Academic Article
|
Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
|
Academic Article
|
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
|
Academic Article
|
Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
|
Academic Article
|
Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies.
|
Academic Article
|
Decreased lifespan in female "Munchkin" actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity.
|
Academic Article
|
Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
|
Academic Article
|
Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease.
|
Academic Article
|
Increased pulse wave velocity is related to impaired working memory and executive function in older adults with metabolic syndrome.
|
Academic Article
|
Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor.
|
Academic Article
|
The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms.
|
Academic Article
|
Psychological resilience and competence: key promoters of successful aging and flourishing in late life.
|
Academic Article
|
Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin.
|
Academic Article
|
Cerebral small vessel disease pathology in COVID-19 patients: A systematic review.
|
Academic Article
|
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
|
Academic Article
|
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
|
Academic Article
|
Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study.
|
Academic Article
|
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.
|
Academic Article
|
Noninvasive low-level tragus stimulation attenuates inflammation and oxidative stress in acute heart failure.
|
Academic Article
|
The Nociceptin/Orphanin FQ peptide receptor antagonist, SB-612111, improves cerebral blood flow in a rat model of traumatic brain injury.
|
Academic Article
|
Noninvasive low-level tragus stimulation attenuates inflammation and oxidative stress in acute heart failure.
|
Academic Article
|
Whole brain irradiation-induced endothelial dysfunction in the mouse brain.
|
Academic Article
|
The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment.
|
Academic Article
|
Survival and longevity of European rulers: geographical influences and exploring potential factors, including the Mediterranean diet - a historical analysis from 1354 to the twentieth century.
|
Academic Article
|
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
|
Academic Article
|
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging.
|
Academic Article
|
Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype.
|
Academic Article
|
A role for the cystathionine-?-synthase /H2S axis in astrocyte dysfunction in the aging brain.
|
Academic Article
|
PCSK9: an emerging player in cardiometabolic aging and its potential as a therapeutic target and biomarker.
|
Academic Article
|
Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors.
|
Academic Article
|
Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction.
|
Academic Article
|
Dimension-based quantification of aging-associated cerebral microvasculature determined by optical coherence tomography and two-photon microscopy.
|
Academic Article
|
Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence.
|