| Item Type | Name |
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Knockout
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Concept
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Mice
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Academic Article
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Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
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Academic Article
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Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia.
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Academic Article
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Measures of Healthspan as Indices of Aging in Mice-A Recommendation.
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Academic Article
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Role of DNA methylation in the dietary restriction mediated cellular memory.
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Academic Article
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Sexually divergent DNA methylation patterns with hippocampal aging.
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Academic Article
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Revisiting the genomic hypomethylation hypothesis of aging.
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Academic Article
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Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice.
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Academic Article
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Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.
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Academic Article
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Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice.
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Academic Article
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Cancer cachexia in a mouse model of oxidative stress.
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Academic Article
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The in vivo gene expression signature of oxidative stress.
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Academic Article
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How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story.
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Academic Article
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The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging.
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Academic Article
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Effect of rapamycin on aging and age-related diseases-past and future.
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Academic Article
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Reproducibility, sources of variability, pooling, and sample size: important considerations for the design of high-density oligonucleotide array experiments.
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Academic Article
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Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice.
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Academic Article
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Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation.
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Academic Article
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Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness.
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Academic Article
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Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype.
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Academic Article
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A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse.
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Academic Article
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Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
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Academic Article
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Necroptosis increases with age and is reduced by dietary restriction.
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Academic Article
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Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
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Academic Article
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Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia.
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Grant
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BLR&D Research Career Scientist Award Application
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Grant
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Can Rapamycin Retard Age-Related Diseases?
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Grant
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TESTING THE ABILITY OF NOVEL ASSAYS OF RESILIENCE TO PREDICT LIFESPAN
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Grant
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Does overexpressing Cu/Zn superoxide dismutase retard aging in rodents
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Grant
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Summer Training Course in Aging Research
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Grant
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Multiplex Protein Quantification Core
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Grant
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Does Dietary Restriction Alter Stem Cell Function Through An Epigenetic Mechanism?
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Grant
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Interaction of Genotype and Level of Dietary Restriction on Lifespan and Aging
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Grant
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NUTRITIONAL PROBE OF THE AGING PROCESS
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Grant
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Protein Oxidation as a Factor in the Mechanism of Aging
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Grant
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TRANSGENIC MICE, AGING, CANCER, AND OXIDATIVE DAMAGE
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Grant
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EFFECT OF DIETARY RESTRICTION ON GENE EXPRESSION
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Academic Article
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Calorie restriction prevents age-related changes in the intestinal microbiota.
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Academic Article
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Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia.
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Academic Article
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Litter expansion alters metabolic homeostasis in a sex specific manner.
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Academic Article
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Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function.
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Academic Article
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Reevaluation of the effect of dietary restriction on different recombinant inbred lines of male and female mice.
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Academic Article
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Necroptosis increases with age in the brain and contributes to age-related neuroinflammation.
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Academic Article
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Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia.
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Academic Article
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Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
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Academic Article
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Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.
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Academic Article
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Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases.
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Academic Article
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Senolytic treatment does not mitigate oxidative stress-induced muscle atrophy but improves muscle force generation in CuZn superoxide dismutase knockout mice.
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Academic Article
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Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages.
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Academic Article
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Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model.
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Academic Article
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MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model.
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Academic Article
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Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases.
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