| Item Type | Name |
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Concept
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Animals
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Concept
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Animals, Newborn
|
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Concept
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Calcium
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Concept
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Carbazoles
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Concept
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Dependovirus
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Concept
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Color Vision Defects
|
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Concept
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Enzyme-Linked Immunosorbent Assay
|
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Concept
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Cyclic GMP
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Concept
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Guanylate Cyclase
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Concept
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Humans
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Concept
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Gene Expression Regulation
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Concept
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Genes, Synthetic
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Concept
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Genetic Vectors
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Concept
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Light
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Concept
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Macular Degeneration
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Concept
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Mutation
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Concept
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Iodide Peroxidase
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Concept
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Mice, Inbred C57BL
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Concept
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Phenoxyacetates
|
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Concept
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Models, Biological
|
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Concept
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Phosphoric Diester Hydrolases
|
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Concept
|
Photoreceptor Cells
|
|
Concept
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Retina
|
|
Concept
|
Retinoblastoma
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|
Concept
|
Antithyroid Agents
|
|
Concept
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Transduction, Genetic
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|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
In Situ Nick-End Labeling
|
|
Concept
|
Photoreceptor Cells, Vertebrate
|
|
Concept
|
Mice, Knockout
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|
Concept
|
cis-trans-Isomerases
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|
Concept
|
Ryanodine Receptor Calcium Release Channel
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|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
Mice
|
|
Concept
|
Cyclic Nucleotide-Gated Cation Channels
|
|
Concept
|
Triiodothyronine
|
|
Concept
|
Retinal Pigment Epithelium
|
|
Concept
|
Opsins
|
|
Concept
|
Cone Opsins
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Receptors, N-Methyl-D-Aspartate
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Inositol 1,4,5-Trisphosphate Receptors
|
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
|
Concept
|
Retinal Cone Photoreceptor Cells
|
|
Concept
|
Unfolded Protein Response
|
|
Concept
|
Injections, Intraocular
|
|
Concept
|
Heterotrimeric GTP-Binding Proteins
|
|
Concept
|
Cell Survival
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Methimazole
|
|
Academic Article
|
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function.
|
|
Academic Article
|
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
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|
Academic Article
|
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.
|
|
Academic Article
|
Thyroid Hormone Signaling in Retinal Development, Survival, and Disease.
|
|
Academic Article
|
Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency.
|
|
Academic Article
|
cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.
|
|
Academic Article
|
The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility.
|
|
Academic Article
|
Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency.
|
|
Academic Article
|
Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.
|
|
Academic Article
|
Inhibition of thyroid hormone signaling protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration.
|
|
Academic Article
|
Preservation of endoplasmic reticulum (ER) Ca2+ stores by deletion of inositol-1,4,5-trisphosphate receptor type 1 promotes ER retrotranslocation, proteostasis, and protein outer segment localization in cyclic nucleotide-gated channel-deficient cone photoreceptors.
|
|
Academic Article
|
Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration.
|
|
Academic Article
|
Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency.
|
|
Academic Article
|
cGMP Signaling in Photoreceptor Degeneration.
|
|
Academic Article
|
Excessive Thyroid Hormone Signaling Induces Photoreceptor Degeneration in Mice.
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