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Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.
Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin.
Deletion of a 19-Amino-Acid Region in Clostridioides difficile TcdB2 Results in Spontaneous Autoprocessing and Reduced Cell Binding and Provides a Nontoxic Immunogen for Vaccination.