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Cook, Paul

One or more keywords matched the following items that are connected to Cook, Paul

Item Type	Name
Concept	Alanine
Concept	beta-Alanine
Concept	Alanine Dehydrogenase
Academic Article	Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase.
Academic Article	Purification and properties of beta-alanine synthase from calf liver.
Academic Article	Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Academic Article	Formation of the alpha-aminoacrylate immediate limits the overall reaction catalyzed by O-acetylserine sulfhydrylase.
Academic Article	Mapping the active site topography of the NAD-malic enzyme via alanine-scanning site-directed mutagenesis.
Academic Article	Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases.
Academic Article	Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Academic Article	Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
Academic Article	A change in the internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transimination and as a general base catalyst.
Academic Article	Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Academic Article	Kinetic mechanism of serine transacetylase from Salmonella typhimurium.
Academic Article	Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Academic Article	Lysine 199 is the general acid in the NAD-malic enzyme reaction.
Academic Article	Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Academic Article	Overall mechanism and rate equation for O-acetylserine sulfhydrylase.
Academic Article	Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants.
Grant	Lysine Biosynthesis in Yeast

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Alanine