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Cook, Paul

One or more keywords matched the following items that are connected to Cook, Paul

Item Type	Name
Concept	Oxidation-Reduction
Academic Article	Alpha-secondary tritium kinetic isotope effects indicate hydrogen tunneling and coupled motion occur in the oxidation of L-malate by NAD-malic enzyme.
Academic Article	Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Metal ion activator effects on intrinsic isotope effects for hydride transfer from decarboxylation in the reaction catalyzed by the NAD-malic enzyme from Ascaris suum.
Academic Article	Secondary tritium and solvent deuterium isotope effects as a probe of the reaction catalyzed by porcine recombinant dihydropyrimidine dehydrogenase.
Academic Article	Oxidative decarboxylation of 6-phosphogluconate by 6-phosphogluconate dehydrogenase proceeds by a stepwise mechanism with NADP and APADP as oxidants.
Academic Article	Kinetic mechanism of NAD:malic enzyme from Ascaris suum in the direction of reductive carboxylation.
Academic Article	Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction.
Academic Article	Protonation mechanism and location of rate-determining steps for the Ascaris suum nicotinamide adenine dinucleotide-malic enzyme reaction from isotope effects and pH studies.
Academic Article	Stepwise versus concerted oxidative decarboxylation catalyzed by malic enzyme: a reinvestigation.
Academic Article	Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.
Academic Article	A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases.
Academic Article	The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
Academic Article	Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis.
Academic Article	pH dependence of kinetic parameters for oxalacetate decarboxylation and pyruvate reduction reactions catalyzed by malic enzyme.
Academic Article	The pH dependence of the reductive carboxylation of pyruvate by malic enzyme.
Academic Article	Acid base catalytic mechanism of the dihydropyrimidine dehydrogenase from pH studies.
Academic Article	Pre-steady-state kinetics reveal a slow isomerization of the enzyme-NAD complex in the NAD-malic enzyme reaction.
Academic Article	Overall kinetic mechanism of 6-phosphogluconate dehydrogenase from Candida utilis.

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Oxidation Reduction