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Cook, Paul

One or more keywords matched the following items that are connected to Cook, Paul

Item Type	Name
Concept	Phosphofructokinase-1
Concept	Phosphofructokinase-2
Academic Article	Kinetic characterization of a T-state of Ascaris suum phosphofructokinase with heterotropic negative cooperativity by ATP eliminated.
Academic Article	Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase.
Academic Article	Optimum activity of the phosphofructokinase from Ascaris suum requires more than one metal ion.
Academic Article	pH dependence of the kinetic parameters for the pyrophosphate-dependent phosphofructokinase reaction supports a proton-shuttle mechanism.
Academic Article	Inactivation of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii by pyridoxal 5'-phosphate. Determination of the pH dependence of enzyme-reactant dissociation constants from protection against inactivation.
Academic Article	Isotope exchange as a probe of the kinetic mechanism of pyrophosphate-dependent phosphofructokinase.
Academic Article	Kinetic mechanism of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii.
Academic Article	Acid-base catalytic mechanism and pH dependence of fructose 2,6-bisphosphate activation of the Ascaris suum phosphofructokinase.
Academic Article	Isotope partitioning with Ascaris suum phosphofructokinase is consistent with an ordered kinetic mechanism.
Academic Article	Effector-induced conformational transitions in Ascaris suum phosphofructokinase. A fluorescence and circular dichroism study.
Academic Article	Fructose 2,6-bisphosphate and AMP increase the affinity of the Ascaris suum phosphofructokinase for fructose 6-phosphate in a process separate from the relief of ATP inhibition.
Academic Article	Modification of the ATP inhibitory site of the Ascaris suum phosphofructokinase results in the stabilization of an inactive T state.
Academic Article	Correlation between hysteresis and allosteric properties for phosphofructokinase from Ascaris suum.
Academic Article	Reaction of Ascaris suum phosphofructokinase with diethylpyrocarbonate. Inactivation and desensitization to allosteric modulation.
Academic Article	Kinetic mechanism of Ascaris suum phosphofructokinase desensitized to allosteric modulation by diethylpyrocarbonate modification.
Academic Article	Carbohydrate substrate specificity of bacterial and plant pyrophosphate-dependent phosphofructokinases.
Academic Article	Kinetic studies on the activation of pyrophosphate-dependent phosphofructokinase from mung bean by fructose 2,6-bisphosphate and related compounds.
Academic Article	Lanthanide pyrophosphates as substrates for the pyrophosphate-dependent phosphofructokinases from Propionibacterium freudenreichii and Phaseolus aureus: evidence for a second metal ion required for reaction.
Academic Article	Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway.
Academic Article	Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
Academic Article	A pH-dependent allosteric transition in Ascaris suum phosphofructokinase distinct from that observed with fructose 2,6-bisphosphate.
Academic Article	Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues.

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Phosphofructokinase 2