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Cook, Paul

One or more keywords matched the following items that are connected to Cook, Paul

Item Type	Name
Concept	Serine
Concept	L-Serine Dehydratase
Concept	Serine O-Acetyltransferase
Academic Article	pH dependence of the absorbance and 31P NMR spectra of O-acetylserine sulfhydrylase in the absence and presence of O-acetyl-L-serine.
Academic Article	Kinetic isotope effects as a probe of the beta-elimination reaction catalyzed by O-acetylserine sulfhydrylase.
Academic Article	Substitution of pyridoxal 5'-phosphate in D-serine dehydratase from Escherichia coli by cofactor analogues provides information on cofactor binding and catalysis.
Academic Article	Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum.
Academic Article	Kinetic mechanism of the serine acetyltransferase from Haemophilus influenzae.
Academic Article	Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Academic Article	Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Academic Article	Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate.
Academic Article	Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae.
Academic Article	A two-step process controls the formation of the bienzyme cysteine synthase complex.
Academic Article	Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase.
Academic Article	Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
Academic Article	Kinetic mechanism of serine transacetylase from Salmonella typhimurium.
Academic Article	Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Academic Article	Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase.
Academic Article	Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Academic Article	Chemical mechanism of the serine acetyltransferase from Haemophilus influenzae.
Academic Article	The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol.
Academic Article	Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy.
Academic Article	Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum.
Academic Article	salmonella typhimurium/enzymol.
Academic Article	Cysteine synthetase from Salmonella typhimurium LT-2. Aggregation, kinetic behavior, and effect of modifiers.
Academic Article	A reaction mechanism from steady state kinetic studies for O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2.
Academic Article	Overall mechanism and rate equation for O-acetylserine sulfhydrylase.
Academic Article	Identification and spectral characterization of the external aldimine of the O-acetylserine sulfhydrylase reaction.
Academic Article	Acid-base chemical mechanism of O-acetylserine sulfhydrylases-A and -B from pH studies.
Academic Article	Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants.
Grant	MECHANISM OF CAMP DEPENDENT PROTEIN KINASE 16.

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Serine