| Item Type | Name |
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Concept
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Glucose-6-Phosphate Isomerase
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Concept
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Glutathione Transferase
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Concept
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Phosphates
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Concept
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Phosphatidylinositols
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Concept
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Pyridoxal Phosphate
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Concept
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Sugar Phosphates
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Concept
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Amino Acid Substitution
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Concept
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Triose-Phosphate Isomerase
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Academic Article
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Time-resolved fluorescence of O-acetylserine sulfhydrylase.
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Academic Article
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Pyridoxal 5'-phosphate-dependent alpha,beta-elimination reactions: mechanism of O-acetylserine sulfhydrylase.
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Academic Article
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Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.
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Academic Article
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Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system.
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Academic Article
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Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction.
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Academic Article
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Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes.
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Academic Article
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Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction.
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Academic Article
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Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
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Academic Article
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Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
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Academic Article
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The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase.
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Academic Article
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Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
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Academic Article
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Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.
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Academic Article
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pH dependence of the absorbance and 31P NMR spectra of O-acetylserine sulfhydrylase in the absence and presence of O-acetyl-L-serine.
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Academic Article
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Inactivation of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii by pyridoxal 5'-phosphate. Determination of the pH dependence of enzyme-reactant dissociation constants from protection against inactivation.
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Academic Article
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Lysine 183 is the general base in the 6-phosphogluconate dehydrogenase-catalyzed reaction.
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Academic Article
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Substitution of pyridoxal 5'-phosphate in D-serine dehydratase from Escherichia coli by cofactor analogues provides information on cofactor binding and catalysis.
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Academic Article
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(31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
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Academic Article
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Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A.
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Academic Article
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Fructose 2,6-bisphosphate and AMP increase the affinity of the Ascaris suum phosphofructokinase for fructose 6-phosphate in a process separate from the relief of ATP inhibition.
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Academic Article
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Kinetic studies on the activation of pyrophosphate-dependent phosphofructokinase from mung bean by fructose 2,6-bisphosphate and related compounds.
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Academic Article
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pH studies toward the elucidation of the auxiliary catalyst for pig heart aspartate aminotransferase.
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Academic Article
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Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
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Academic Article
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A change in the internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transimination and as a general base catalyst.
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Academic Article
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O-acetylserine sulfhydrylase.
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Academic Article
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Ascaris suum NAD-malic enzyme is activated by L-malate and fumarate binding to separate allosteric sites.
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Academic Article
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Importance in catalysis of the 6-phosphate-binding site of 6-phosphogluconate in sheep liver 6-phosphogluconate dehydrogenase.
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Academic Article
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Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae.
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Academic Article
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Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase.
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Academic Article
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Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.
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Academic Article
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Lanthanide pyrophosphates as substrates for the pyrophosphate-dependent phosphofructokinases from Propionibacterium freudenreichii and Phaseolus aureus: evidence for a second metal ion required for reaction.
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Academic Article
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Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
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Academic Article
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Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium.
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Academic Article
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Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
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Academic Article
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Lysine 199 is the general acid in the NAD-malic enzyme reaction.
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Academic Article
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Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound.
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Academic Article
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Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase.
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Academic Article
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Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
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Academic Article
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Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy.
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Academic Article
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The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase.
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Academic Article
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Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme.
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Academic Article
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(31)P NMR spectroscopy senses the microenvironment of the 5'-phosphate group of enzyme-bound pyridoxal 5'-phosphate.
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Academic Article
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The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
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Academic Article
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Resolution of pyridoxal 5'-phosphate from O-acetylserine sulfhydrylase from Salmonella typhimurium and reconstitution of apoenzyme with cofactor and cofactor analogues as a probe of the cofactor binding site.
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Academic Article
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Acid-base chemical mechanism of O-acetylserine sulfhydrylases-A and -B from pH studies.
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Academic Article
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The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis.
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Academic Article
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Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues.
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Grant
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STRUCTURE AND MECHANISM OF NAD-MALIC ENZYME
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Grant
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STRUCTURE/MECHANISM OF 6-PHOSPHOGLUCONATE DEHYDROGENASE
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