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Cell Cycle Proteins
Cell Cycle Checkpoints
G2 Phase Cell Cycle Checkpoints
G1 Phase Cell Cycle Checkpoints
Resting Phase, Cell Cycle
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.
HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.
Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity.
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage.
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells.
Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
HuR Targeted Nanotherapy for Lung Cancer