| Item Type | Name |
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Concept
|
NF-KappaB Inhibitor alpha
|
|
Concept
|
ELAV-Like Protein 1
|
|
Concept
|
Bevacizumab
|
|
Concept
|
Quaternary Ammonium Compounds
|
|
Concept
|
Theranostic Nanomedicine
|
|
Concept
|
Adjuvants, Immunologic
|
|
Concept
|
Administration, Oral
|
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Concept
|
Antibodies, Monoclonal
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|
Concept
|
Antibodies, Neoplasm
|
|
Concept
|
Caffeine
|
|
Concept
|
Cisplatin
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Doxorubicin
|
|
Concept
|
Doxycycline
|
|
Concept
|
Fibroblast Growth Factors
|
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Concept
|
Drug Synergism
|
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Concept
|
Humans
|
|
Concept
|
Gelatin
|
|
Concept
|
Liposomes
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Concept
|
Luciferases
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Concept
|
Glycosylation
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Interleukins
|
|
Concept
|
Naproxen
|
|
Concept
|
Neoplastic Cells, Circulating
|
|
Concept
|
Neoplasm Invasiveness
|
|
Concept
|
Neoplasm Metastasis
|
|
Concept
|
Neoplasm Transplantation
|
|
Concept
|
Neoplasms, Experimental
|
|
Concept
|
Platelet-Derived Growth Factor
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Phagocytosis
|
|
Concept
|
Polyesters
|
|
Concept
|
Polyethylene Glycols
|
|
Concept
|
Polymers
|
|
Concept
|
Mitochondria
|
|
Concept
|
Phosphoric Monoester Hydrolases
|
|
Concept
|
Phosphoprotein Phosphatases
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Predictive Value of Tests
|
|
Concept
|
Pancreatic Neoplasms
|
|
Concept
|
Refractometry
|
|
Concept
|
Peptide Fragments
|
|
Concept
|
Thioredoxin-Disulfide Reductase
|
|
Concept
|
Periodicals as Topic
|
|
Concept
|
Tissue Distribution
|
|
Concept
|
Radiation-Sensitizing Agents
|
|
Concept
|
Technology, Pharmaceutical
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Interleukin-10
|
|
Concept
|
Sulindac
|
|
Concept
|
Triptorelin Pamoate
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Pharmaceutical Vehicles
|
|
Concept
|
Protein Tyrosine Phosphatases
|
|
Concept
|
Vitamin E
|
|
Concept
|
Oxidative Stress
|
|
Concept
|
Drug Resistance, Multiple
|
|
Concept
|
Disease Progression
|
|
Concept
|
Chemokines
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Microscopy, Atomic Force
|
|
Concept
|
Drug Resistance, Neoplasm
|
|
Concept
|
fas Receptor
|
|
Concept
|
src-Family Kinases
|
|
Concept
|
Oligonucleotides, Antisense
|
|
Concept
|
Inhibitory Concentration 50
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Angiogenesis Inhibitors
|
|
Concept
|
Caspases
|
|
Concept
|
Fluorescein-5-isothiocyanate
|
|
Concept
|
Macrophages, Alveolar
|
|
Concept
|
I-kappa B Proteins
|
|
Concept
|
Maximum Tolerated Dose
|
|
Concept
|
Surface Plasmon Resonance
|
|
Concept
|
Matrix Metalloproteinase 2
|
|
Concept
|
Matrix Metalloproteinase 9
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
Receptors, CXCR4
|
|
Concept
|
Chemokines, CXC
|
|
Concept
|
O(6)-Methylguanine-DNA Methyltransferase
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
eIF-2 Kinase
|
|
Concept
|
Biotinylation
|
|
Concept
|
Endostatins
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Tocopherols
|
|
Concept
|
Nanotubes
|
|
Concept
|
Prostatic Neoplasms
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Protein-Tyrosine Kinases
|
|
Concept
|
Tumor Suppressor Proteins
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Proto-Oncogenes
|
|
Concept
|
HMGA1a Protein
|
|
Concept
|
Nanomedicine
|
|
Concept
|
Apoptosis Regulatory Proteins
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
Mice
|
|
Concept
|
Focal Adhesion Protein-Tyrosine Kinases
|
|
Concept
|
Focal Adhesion Kinase 1
|
|
Concept
|
Optical Devices
|
|
Concept
|
Tubulin
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Tunicamycin
|
|
Concept
|
Drug Liberation
|
|
Concept
|
Umbilical Veins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
RNA-Binding Protein FUS
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Biomedical Research
|
|
Concept
|
Capsid Proteins
|
|
Concept
|
Nanotechnology
|
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Cytokines
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Nanotubes, Carbon
|
|
Concept
|
Immunoprecipitation
|
|
Concept
|
ErbB Receptors
|
|
Concept
|
Chitosan
|
|
Concept
|
MAP Kinase Kinase Kinase 1
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Nanostructures
|
|
Concept
|
Integrin alphaVbeta3
|
|
Concept
|
Fas Ligand Protein
|
|
Concept
|
Caspase 9
|
|
Concept
|
Caspase 12
|
|
Concept
|
Nanoparticles
|
|
Concept
|
Metal Nanoparticles
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Radiopharmaceuticals
|
|
Concept
|
Dendrimers
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Chemokine CXCL10
|
|
Concept
|
Polycomb Repressive Complex 1
|
|
Concept
|
Chemokine CXCL12
|
|
Concept
|
Protein Phosphatase 1
|
|
Concept
|
Protein Phosphatase 2
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Magnetite Nanoparticles
|
|
Concept
|
Muscle Cells
|
|
Concept
|
TOR Serine-Threonine Kinases
|
|
Concept
|
Caspase 3
|
|
Concept
|
Caspase 7
|
|
Concept
|
Receptors, TNF-Related Apoptosis-Inducing Ligand
|
|
Concept
|
TNF-Related Apoptosis-Inducing Ligand
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Small Cell Lung Carcinoma
|
|
Concept
|
Drug Discovery
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
Antibodies, Monoclonal, Humanized
|
|
Concept
|
Chemistry, Pharmaceutical
|
|
Concept
|
DNA
|
|
Concept
|
DNA Damage
|
|
Concept
|
DNA Helicases
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescamine
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Folic Acid
|
|
Concept
|
Hypoglycemic Agents
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Mebendazole
|
|
Concept
|
Medical Oncology
|
|
Concept
|
Melanoma
|
|
Concept
|
Oligopeptides
|
|
Concept
|
Oncogenes
|
|
Concept
|
Ovarian Neoplasms
|
|
Academic Article
|
Chitosan coated polylactic acid nanoparticle-mediated combinatorial delivery of cisplatin and siRNA/Plasmid DNA chemosensitizes cisplatin-resistant human ovarian cancer cells.
|
|
Academic Article
|
HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy.
|
|
Academic Article
|
Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells.
|
|
Academic Article
|
Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy.
|
|
Academic Article
|
HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A.
|
|
Academic Article
|
Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage.
|
|
Academic Article
|
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.
|
|
Academic Article
|
Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells.
|
|
Academic Article
|
Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy.
|
|
Academic Article
|
On the issue of transparency and reproducibility in nanomedicine.
|
|
Academic Article
|
Increased uptake of liposomal-DNA complexes by lung metastases following intravenous administration.
|
|
Academic Article
|
Cytokine- and chemokine-based gene therapy for cancer.
|
|
Academic Article
|
Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells.
|
|
Academic Article
|
Local and systemic inhibition of lung tumor growth after nanoparticle-mediated mda-7/IL-24 gene delivery.
|
|
Academic Article
|
Targeted drug and gene delivery systems for lung cancer therapy.
|
|
Academic Article
|
IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis.
|
|
Academic Article
|
Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity.
|
|
Academic Article
|
Surface plasmon resonance imaging of gold-small molecule interactions is influenced by refractive index and chemical structures.
|
|
Academic Article
|
IL-24 modulates the high mobility group (HMG) A1/miR222 /AKT signaling in lung cancer cells.
|
|
Academic Article
|
Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo.
|
|
Academic Article
|
Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells.
|
|
Academic Article
|
Determinant role for the gep oncogenes, Ga12/13, in ovarian cancer cell proliferation and xenograft tumor growth.
|
|
Academic Article
|
MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells.
|
|
Academic Article
|
Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.
|
|
Academic Article
|
The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
|
|
Academic Article
|
Persistent transgene expression following intravenous administration of a liposomal complex: role of interleukin-10-mediated immune suppression.
|
|
Academic Article
|
Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
|
|
Academic Article
|
MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo.
|
|
Academic Article
|
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
|
|
Academic Article
|
Cancer targeting using tumor suppressor genes.
|
|
Academic Article
|
Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer.
|
|
Academic Article
|
EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells.
|
|
Academic Article
|
Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
|
|
Academic Article
|
EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage.
|
|
Academic Article
|
Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment.
|
|
Academic Article
|
IL-24 Inhibits Lung Cancer Growth by Suppressing GLI1 and Inducing DNA Damage.
|
|
Academic Article
|
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
|
|
Academic Article
|
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
|
|
Academic Article
|
MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
|
|
Academic Article
|
Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells.
|
|
Academic Article
|
Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response.
|
|
Academic Article
|
Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
|
|
Academic Article
|
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
|
|
Academic Article
|
Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells.
|
|
Academic Article
|
Vitamin E succinate in combination with mda-7 results in enhanced human ovarian tumor cell killing through modulation of extrinsic and intrinsic apoptotic pathways.
|
|
Academic Article
|
Nanoparticle-mediated gene delivery to the lung.
|
|
Academic Article
|
Structural mapping of post-translational modifications in human interleukin-24: role of N-linked glycosylation and disulfide bonds in secretion and activity.
|
|
Academic Article
|
YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways.
|
|
Grant
|
HuR Targeted Nanotherapy for Lung Cancer
|
|
Grant
|
Evaluate the antiangiogenic properties of mda-7/IL-24
|
|
Grant
|
Systemic Non-Viral Gene Therapy for Cancer
|
|
Grant
|
Preclinical Development and Testing of Multifunctional Tumor-Targeted Hybrid Nano
|
|
Grant
|
Molecular Impact of Platinum Drugs on the Proteasome and SQSTM1_P62 Complexes_A Paradigm Shift in Resistance
|
|
Grant
|
ShEEP Request for CytoViva 3D Darkfield Hyperspectral Microscope
|
|
Academic Article
|
Extracellular Vesicles in Oncology: from Immune Suppression to Immunotherapy.
|
|
Academic Article
|
Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment.
|
|
Academic Article
|
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer.
|
|
Academic Article
|
Harnessing small extracellular vesicles for pro-oxidant delivery: novel approach for drug-sensitive and resistant cancer therapy.
|
|
Grant
|
Native American Youths Enjoy Science - YES Oklahoma
|
|
Academic Article
|
Exosomes in diagnostic and therapeutic applications of ovarian cancer.
|
|
Academic Article
|
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment.
|