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MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells.
mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells.
Phosphatidylinositol 3 Kinases