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Matts, Robert

One or more keywords matched the following items that are connected to Matts, Robert

Item Type	Name
Concept	Phosphotransferases
Concept	src-Family Kinases
Concept	Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Concept	eIF-2 Kinase
Concept	Protein Kinases
Concept	Protein-Tyrosine Kinases
Concept	Cyclin-Dependent Kinase 2
Concept	Focal Adhesion Kinase 2
Concept	Protein Kinase Inhibitors
Concept	MAP Kinase Kinase 4
Academic Article	Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase.
Academic Article	High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients.
Academic Article	Functional dissection of cdc37: characterization of domain structure and amino acid residues critical for protein kinase binding.
Academic Article	Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions.
Academic Article	Definition of protein kinase sequence motifs that trigger high affinity binding of Hsp90 and Cdc37.
Academic Article	Interdomain interactions regulate the activation of the heme-regulated eIF 2 alpha kinase.
Academic Article	Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates.
Academic Article	Evidence for the association of the heme-regulated eIF-2 alpha kinase with the 90-kDa heat shock protein in rabbit reticulocyte lysate in situ.
Academic Article	Effect of interferon on protein translation during growth stages of 3T3 cells.
Academic Article	Changes in the expression of the heme-regulated eIF-2 alpha kinase and heat shock proteins in rabbit reticulocytes maturing during recovery from anemia.
Academic Article	Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2.
Academic Article	The heme-regulated eukaryotic initiation factor 2alpha kinase. A potential regulatory target for control of protein synthesis by diffusible gases.
Academic Article	Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase.
Academic Article	Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2alpha kinase.
Academic Article	Toxic heavy metal ions activate the heme-regulated eukaryotic initiation factor-2 alpha kinase by inhibiting the capacity of hemin-supplemented reticulocyte lysates to reduce disulfide bonds.
Academic Article	Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function.
Academic Article	Denatured proteins inhibit translation in hemin-supplemented rabbit reticulocyte lysate by inducing the activation of the heme-regulated eIF-2 alpha kinase.
Academic Article	Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate.
Academic Article	Hsp90-mediated folding of the lymphoid cell kinase p56lck.
Academic Article	Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase.
Academic Article	The N-terminal region of the heme-regulated eIF2alpha kinase is an autonomous heme binding domain.
Academic Article	Two heme-binding domains of heme-regulated eukaryotic initiation factor-2alpha kinase. N terminus and kinase insertion.
Academic Article	Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases.
Academic Article	The molecular chaperone Hsp90 is required for signal transduction by wild-type Hck and maintenance of its constitutively active counterpart.
Academic Article	Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation.
Academic Article	Exposure of protein kinase motifs that trigger binding of Hsp90 and Cdc37.
Academic Article	Cdk2: a genuine protein kinase client of Hsp90 and Cdc37.
Academic Article	Phosphorothioated binary complex of eukaryotic initiation factor eIF-2 and GDP inhibits protein synthesis in hemin-supplemented reticulocyte lysates.
Academic Article	Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation.
Academic Article	Evidence that Hsc70 negatively modulates the activation of the heme-regulated eIF-2alpha kinase in rabbit reticulocyte lysate.
Academic Article	p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules.
Academic Article	p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.
Academic Article	NO-induced activation mechanism of the heme-regulated eIF2alpha kinase.
Academic Article	Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.
Academic Article	The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress.
Academic Article	Cisplatin inhibits protein synthesis in rabbit reticulocyte lysate by causing an arrest in elongation.
Grant	LCK TYROSINE KINASE/HEAT SHOCK PROTEIN INTERACTIONS
Grant	HEAVY METAL IONS--EUKARYOTIC PROTEIN SYNTHESIS
Grant	LCK TYROSINE KINASE/HEAT SHOCK PROTEIN INTERACTION
Grant	EFFECT OF HEAVY METAL IONS--EUKARYOTIC PROTEIN SYNTHESIS

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Phosphotransferases