| Item Type | Name |
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Concept
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Alleles
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Concept
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Amino Acid Sequence
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Concept
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Base Sequence
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Concept
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Epistasis, Genetic
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Concept
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Gene Expression Regulation
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Concept
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Gene Frequency
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Concept
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Genes, Dominant
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Concept
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Genes, Immunoglobulin
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Concept
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Genes, Recessive
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Concept
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Major Histocompatibility Complex
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Concept
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Molecular Sequence Data
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Concept
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Genes, ras
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Concept
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Genomic Library
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Concept
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Gene Rearrangement
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Concept
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Gene Deletion
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Concept
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Sequence Homology, Amino Acid
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Concept
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Genes, cdc
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Concept
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Genome, Protozoan
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Concept
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Gene Expression Regulation, Developmental
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Concept
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Gene Dosage
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Concept
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Catalytic Domain
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Genetic Pleiotropy
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Concept
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Metagenome
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Concept
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Gene Expression
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Concept
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Genome, Human
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Concept
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Gene Expression Regulation, Neoplastic
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Concept
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Transcriptome
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Concept
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Exome
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Concept
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Genes, Tumor Suppressor
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Concept
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Genes, myc
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Concept
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Gene Regulatory Networks
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Concept
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Quantitative Trait Loci
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Concept
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Gene Expression Profiling
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Concept
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Gene Order
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Concept
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Gene Knockdown Techniques
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Concept
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Gene Knockout Techniques
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Concept
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Genetic Loci
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Academic Article
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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.
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Academic Article
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Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation.
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Academic Article
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Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
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Academic Article
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Complete mitochondrial DNA sequence of the eastern oyster Crassostrea virginica.
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Academic Article
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Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
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Academic Article
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Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
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Academic Article
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Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
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Academic Article
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Genetic associations of LYN with systemic lupus erythematosus.
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Academic Article
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Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
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Academic Article
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Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing.
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Academic Article
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Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC.
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Academic Article
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Peripheral blood gene expression profiling in Sjögren's syndrome.
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Academic Article
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Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
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Academic Article
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Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
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Academic Article
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Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
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Academic Article
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
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Academic Article
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An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression.
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Academic Article
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
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Academic Article
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GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
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Academic Article
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X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.
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Academic Article
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Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck.
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Academic Article
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Gene expression profiling in human autoimmunity.
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Academic Article
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Identification of new SLE-associated genes with a two-step Bayesian study design.
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Academic Article
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The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus.
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Academic Article
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
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Academic Article
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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
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Academic Article
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WITHDRAWN: A female autoimmunity gene exists: DDX3X.
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Academic Article
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Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.
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Academic Article
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MHC associations with clinical and autoantibody manifestations in European SLE.
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Academic Article
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TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus.
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Academic Article
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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
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Academic Article
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Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.
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Academic Article
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Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
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Academic Article
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Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.
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Academic Article
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Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma.
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Academic Article
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Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus.
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Academic Article
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A novel polymorphism of the human CD40 receptor with enhanced function.
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Academic Article
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Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).
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Academic Article
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Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.
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Academic Article
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Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function.
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Academic Article
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Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort.
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Academic Article
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Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
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Academic Article
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Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency.
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Academic Article
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A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
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Academic Article
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Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
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Academic Article
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Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study.
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Academic Article
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Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking.
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Academic Article
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Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.
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Academic Article
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Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
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Academic Article
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Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network.
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Academic Article
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A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.
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Academic Article
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Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc.
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Academic Article
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Keys to unlocking the mysteries of rheumatic autoimmune disease.
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Academic Article
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Fine mapping chromosome 16q12 in a collection of 231 systemic lupus erythematosus sibpair and multiplex families.
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Academic Article
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Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus.
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Academic Article
|
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
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Academic Article
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Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.
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Academic Article
|
Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
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Academic Article
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Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
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Academic Article
|
Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
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Academic Article
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Evaluation of TRAF6 in a large multiancestral lupus cohort.
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Academic Article
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Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
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Academic Article
|
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
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Academic Article
|
PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
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Academic Article
|
Human effector B lymphocytes express ARID3a and secrete interferon alpha.
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Academic Article
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Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
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Academic Article
|
Identification and replication of RNA-Seq gene network modules associated with depression severity.
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Academic Article
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Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.
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Academic Article
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Correction: Identification and replication of RNA-Seq gene network modules associated with depression severity.
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Academic Article
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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
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Academic Article
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Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.
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Grant
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Epigenome-Guided Causal Variant Discovery and Mechanisms
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Grant
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TNFAIP3 (A20) and Susceptibility to Systemic Lupus Erythematosus
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|
Grant
|
Comprehensive Candidate Pathway Analysis in SLE
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Grant
|
Molecular Mechanisms and Genetics of Autoimmunity
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Grant
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Functional Mechanisms of Causal Variants in Systemic Lupus Erythematosus
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Grant
|
Comprehensive Candidate Pathway Analysis in SLE
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Grant
|
ISOLATION OF A HUMAN SLE SUSCEPTIBILITY GENE ON CHROMOSO
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Grant
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Molecular Mechanisms and Genetics of Autoimmunity
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Academic Article
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CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities.
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Academic Article
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Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
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Grant
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Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE
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Academic Article
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Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding.
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Academic Article
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Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis.
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