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Shannon M Conley

TitleProf,Asst
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
AddressBMSB 100
940 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-2493
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    Collapse Research 
    Collapse research activities and funding
    R01AG070915     (CONLEY, SHANNON M)Sep 30, 2021 - May 31, 2026
    NIH
    The role of IGF-1 signaling in vascular smooth muscle cells in age-related vascular cognitive impairment and dementia
    Role: Principal Investigator
    F32EY018512     (CONLEY, SHANNON M)Feb 1, 2009 - Jan 31, 2012
    NIH
    The role of the photoreceptor tetraspanin Rds in outer segment morphogenesis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Miller LR, Bickel MA, Vance ML, Vaden H, Nagykaldi D, Nyul-Toth A, Bullen EC, Gautam T, Tarantini S, Yabluchanskiy A, Kiss T, Ungvari Z, Conley SM. Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects. Geroscience. 2024 Feb 23. PMID: 38388918.
      Citations:    Fields:    
    2. Gulej R, Ny?l-T?th ?, Csik B, Petersen B, Faakye J, Negri S, Chandragiri SS, Mukli P, Yabluchanskiy A, Conley S, Huffman DM, Csiszar A, Tarantini S, Ungvari Z. Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors. Geroscience. 2023 Dec 21. PMID: 38123890.
      Citations:    Fields:    Translation:Animals
    3. Gulej R, Csik B, Faakye J, Tarantini S, Shanmugarama S, Chandragiri SS, Mukli P, Conley S, Csiszar A, Ungvari Z, Yabluchanskiy A, Ny?l-T?th ?. Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype. Microcirculation. 2023 Dec 11; e12840. PMID: 38082450.
      Citations:    Fields:    Translation:AnimalsCells
    4. Faakye J, Ny?l-T?th ?, Muranyi M, Gulej R, Csik B, Shanmugarama S, Tarantini S, Negri S, Prodan C, Mukli P, Yabluchanskiy A, Conley S, Toth P, Csiszar A, Ungvari Z. Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax. Geroscience. 2023 Dec 04. PMID: 38044400.
      Citations:    Fields:    Translation:HumansAnimals
    5. Lewis TR, Makia MS, Castillo CM, Hao Y, Al-Ubaidi MR, Skiba NP, Conley SM, Arshavsky VY, Naash MI. ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims. Elife. 2023 Nov 22; 12. PMID: 37991486; PMCID: PMC10665016.
      Citations:    Fields:    Translation:AnimalsCells
    6. Bickel MA, Sherry DM, Bullen EC, Vance ML, Jones KL, Howard EW, Conley SM. Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1. Microvasc Res. 2023 Sep 15; 151:104609. PMID: 37716411.
      Citations:    Fields:    Translation:AnimalsCells
    7. Ikelle L, Makia M, Lewis T, Crane R, Kakakhel M, Conley SM, Birtley JR, Arshavsky VY, Al-Ubaidi MR, Naash MI. Correction: Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones. Cell Mol Life Sci. 2023 Sep 12; 80(10):290. PMID: 37698644; PMCID: PMC10497654.
      Citations:    Fields:    
    8. Pandics T, Major D, Fazekas-Pongor V, Szarvas Z, Peterfi A, Mukli P, Gulej R, Ungvari A, Fekete M, Tompa A, Tarantini S, Yabluchanskiy A, Conley S, Csiszar A, Tabak AG, Benyo Z, Adany R, Ungvari Z. Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures. Geroscience. 2023 Sep 09. PMID: 37688657.
      Citations:    Fields:    Translation:PHPublic Health
    9. Lewis TR, Makia MS, Castillo CM, Hao Y, Al-Ubaidi MR, Skiba NP, Conley SM, Arshavsky VY, Naash MI. ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims. bioRxiv. 2023 Aug 29. PMID: 37693615; PMCID: PMC10491102.
      Citations:    
    10. Ikelle L, Makia M, Lewis T, Crane R, Kakakhel M, Conley SM, Birtley JR, Arshavsky VY, Al-Ubaidi MR, Naash MI. Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones. Cell Mol Life Sci. 2023 Jul 19; 80(8):214. PMID: 37466729; PMCID: PMC10356684.
      Citations:    Fields:    Translation:HumansCells
    11. Faakye J, Ny?l-T?th ?, Gulej R, Csik B, Tarantini S, Shanmugarama S, Prodan C, Mukli P, Yabluchanskiy A, Conley S, Toth P, Csiszar A, Ungvari Z. Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin. Geroscience. 2023 Jun 20. PMID: 37338779.
      Citations:    Fields:    Translation:Animals
    12. Bickel MA, Csik B, Gulej R, Ungvari A, Nyul-Toth A, Conley SM. Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis. Front Endocrinol (Lausanne). 2023; 14:1087053. PMID: 36755922; PMCID: PMC9900125.
      Citations: 5     Fields:    Translation:Humans
    13. Conley SM, McClard CK, Mwoyosvi ML, Alkadhem N, Radojevic B, Klein M, Birch D, Ellis A, Icks SW, Guddanti T, Bennett LD. Delineating the Clinical Phenotype of Patients With the c.629C>G, p.Pro210Arg Mutation in Peripherin-2. Invest Ophthalmol Vis Sci. 2022 07 08; 63(8):19. PMID: 35861669.
      Citations: 1     Fields:    Translation:Humans
    14. Tebbe L, Sakthivel H, Makia MS, Kakakhel M, Conley SM, Al-Ubaidi MR, Naash MI. Prph2 disease mutations lead to structural and functional defects in the RPE. FASEB J. 2022 05; 36(5):e22284. PMID: 35344225.
      Citations: 2     Fields:    Translation:HumansCells
    15. Miller LR, Tarantini S, Nyúl-Tóth Á, Johnston MP, Martin T, Bullen EC, Bickel MA, Sonntag WE, Yabluchanskiy A, Csiszar A, Ungvari ZI, Elliott MH, Conley SM. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022; 14:788296. PMID: 35356301.
      Citations: 8     
    16. Kiss T, Nyúl-Tóth Á, Gulej R, Tarantini S, Csipo T, Mukli P, Ungvari A, Balasubramanian P, Yabluchanskiy A, Benyo Z, Conley SM, Wren JD, Garman L, Huffman DM, Csiszar A, Ungvari Z. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981. PMID: 35124764.
      Citations: 9     Fields:    Translation:AnimalsCells
    17. Eblimit A, Makia MS, Strayve D, Crane R, Conley SM, Sinha T, Acharya G, Al-Ubaidi MR, Naash MI. Co-Injection of Sulfotyrosine Facilitates Retinal Uptake of Hyaluronic Acid Nanospheres Following Intravitreal Injection. Pharmaceutics. 2021 Sep 18; 13(9). PMID: 34575586.
      Citations:    
    18. Radojevic B, Conley SM, Bennett LD. Adherent but Not Suspension-Cultured Embryoid Bodies Develop into Laminated Retinal Organoids. J Dev Biol. 2021 Sep 10; 9(3). PMID: 34564087.
      Citations: 2     
    19. István L, Czakó C, Élo Á, Mihály Z, Sótonyi P, Varga A, Ungvári Z, Csiszár A, Yabluchanskiy A, Conley S, Csipo T, Lipecz Á, Kovács I, Nagy ZZ. Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment. Geroscience. 2021 08; 43(4):1703-1723. PMID: 34100219.
      Citations: 15     Fields:    Translation:Humans
    20. Crane R, Conley SM, Al-Ubaidi MR, Naash MI. Gene Therapy to the Retina and the Cochlea. Front Neurosci. 2021; 15:652215. PMID: 33815052.
      Citations: 9     
    21. Genc AM, Makia MS, Sinha T, Conley SM, Al-Ubaidi MR, Naash MI. Retbindin: A riboflavin Binding Protein, Is Critical for Photoreceptor Homeostasis and Survival in Models of Retinal Degeneration. Int J Mol Sci. 2020 Oct 29; 21(21). PMID: 33138244.
      Citations: 1     Fields:    Translation:AnimalsCells
    22. Czakó C, Kovács T, Ungvari Z, Csiszar A, Yabluchanskiy A, Conley S, Csipo T, Lipecz A, Horváth H, Sándor GL, István L, Logan T, Nagy ZZ, Kovács I. Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis. Geroscience. 2020 12; 42(6):1499-1525. PMID: 33011937.
      Citations: 44     Fields:    Translation:Humans
    23. Strayve D, Makia MS, Kakakhel M, Sakthivel H, Conley SM, Al-Ubaidi MR, Naash MI. ROM1 contributes to phenotypic heterogeneity in PRPH2-associated retinal disease. Hum Mol Genet. 2020 09 29; 29(16):2708-2722. PMID: 32716032.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    24. Kakakhel M, Tebbe L, Makia MS, Conley SM, Sherry DM, Al-Ubaidi MR, Naash MI. Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival. Proc Natl Acad Sci U S A. 2020 08 25; 117(34):20615-20624. PMID: 32778589.
      Citations: 11     Fields:    Translation:AnimalsCells
    25. Genc AM, Makia MS, Sinha T, Conley SM, Al-Ubaidi MR, Naash MI. Elimination of a Retinal Riboflavin Binding Protein Exacerbates Degeneration in a Model of Cone-Rod Dystrophy. Invest Ophthalmol Vis Sci. 2020 06 03; 61(6):17. PMID: 32516403.
      Citations: 6     Fields:    Translation:Animals
    26. Lipecz A, Miller L, Kovacs I, Czakó C, Csipo T, Baffi J, Csiszar A, Tarantini S, Ungvari Z, Yabluchanskiy A, Conley S. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019 12; 41(6):813-845. PMID: 31797238.
      Citations: 33     Fields:    Translation:Humans
    27. Chakraborty D, Strayve DG, Makia MS, Conley SM, Kakahel M, Al-Ubaidi MR, Naash MI. Novel molecular mechanisms for Prph2-associated pattern dystrophy. FASEB J. 2020 01; 34(1):1211-1230. PMID: 31914632.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    28. Lipecz A, Csipo T, Tarantini S, Hand RA, Ngo BN, Conley S, Nemeth G, Tsorbatzoglou A, Courtney DL, Yabluchanska V, Csiszar A, Ungvari ZI, Yabluchanskiy A. Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience. 2019 06; 41(3):341-349. PMID: 31209739.
      Citations: 40     Fields:    Translation:Humans
    29. Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454. PMID: 29931048.
      Citations: 25     Fields:    Translation:Animals
    30. Conley SM, Stuck MW, Watson JN, Zulliger R, Burnett JL, Naash MI. Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization. Hum Mol Genet. 2019 02 01; 28(3):459-475. PMID: 30307502.
      Citations: 22     Fields:    Translation:AnimalsCells
    31. Conley SM, Al-Ubaidi MR, Naash MI. The Role of the Prph2 C-Terminus in Outer Segment Morphogenesis. Adv Exp Med Biol. 2019; 1185:495-499. PMID: 31884660.
      Citations: 3     Fields:    Translation:HumansCells
    32. Zulliger R, Conley SM, Mwoyosvi ML, Al-Ubaidi MR, Naash MI. Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation. Hum Mol Genet. 2018 10 15; 27(20):3507-3518. PMID: 29961824.
      Citations: 31     Fields:    Translation:AnimalsCells
    33. Agbaga MP, Merriman DK, Brush RS, Lydic TA, Conley SM, Naash MI, Jackson S, Woods AS, Reid GE, Busik JV, Anderson RE. Differential composition of DHA and very-long-chain PUFAs in rod and cone photoreceptors. J Lipid Res. 2018 09; 59(9):1586-1596. PMID: 29986998.
      Citations: 34     Fields:    Translation:AnimalsCells
    34. Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI. DNA nanoparticles are safe and nontoxic in non-human primate eyes. Int J Nanomedicine. 2018; 13:1361-1379. PMID: 29563793.
      Citations: 13     Fields:    Translation:HumansAnimals
    35. Conley SM, Stuck MW, Watson JN, Naash MI. Rom1 converts Y141C-Prph2-associated pattern dystrophy to retinitis pigmentosa. Hum Mol Genet. 2017 02 01; 26(3):509-518. PMID: 28053051.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    36. Chakraborty D, Conley SM, Zulliger R, Naash MI. The K153Del PRPH2 mutation differentially impacts photoreceptor structure and function. Hum Mol Genet. 2016 08 15; 25(16):3500-3514. PMID: 27365499.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    37. Chakraborty D, Conley SM, Pittler SJ, Naash MI. Role of RDS and Rhodopsin in Cngb1-Related Retinal Degeneration. Invest Ophthalmol Vis Sci. 2016 Mar; 57(3):787-97. PMID: 26934134.
      Citations: 7     Fields:    Translation:AnimalsCells
    38. Stuck MW, Conley SM, Naash MI. PRPH2/RDS and ROM-1: Historical context, current views and future considerations. Prog Retin Eye Res. 2016 05; 52:47-63. PMID: 26773759.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    39. Stuck MW, Conley SM, Naash MI. RDS Functional Domains and Dysfunction in Disease. Adv Exp Med Biol. 2016; 854:217-22. PMID: 26427414.
      Citations:    Fields:    Translation:HumansAnimalsCells
    40. Mitra RN, Conley SM, Naash MI. Therapeutic Approach of Nanotechnology for Oxidative Stress Induced Ocular Neurodegenerative Diseases. Adv Exp Med Biol. 2016; 854:463-9. PMID: 26427447.
      Citations: 8     Fields:    Translation:HumansAnimals
    41. Conley SM, Whalen P, Lewin AS, Naash MI. Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Adv Exp Med Biol. 2016; 854:509-15. PMID: 26427453.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    42. Chakraborty D, Conley SM, DeRamus ML, Pittler SJ, Naash MI. Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function. Invest Ophthalmol Vis Sci. 2015 Dec; 56(13):8187-98. PMID: 26720471.
      Citations: 6     Fields:    Translation:AnimalsCells
    43. Zulliger R, Conley SM, Naash MI. Non-viral therapeutic approaches to ocular diseases: An overview and future directions. J Control Release. 2015 Dec 10; 219:471-487. PMID: 26439665.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    44. Stuck MW, Conley SM, Naash MI. Retinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS·ROM-1 Protein Complex Formation. J Biol Chem. 2015 Nov 13; 290(46):27901-13. PMID: 26420485.
      Citations: 15     Fields:    Translation:AnimalsCells
    45. Zulliger R, Conley SM, Mwoyosvi ML, Stuck MW, Azadi S, Naash MI. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015; 10(9):e0138508. PMID: 26406599.
      Citations: 24     Fields:    Translation:AnimalsCells
    46. Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI. Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype. FASEB J. 2015 Jun; 29(6):2535-44. PMID: 25713057.
      Citations: 26     Fields:    Translation:HumansAnimals
    47. Conley SM, Naash MI. Gene therapy for PRPH2-associated ocular disease: challenges and prospects. Cold Spring Harb Perspect Med. 2014 Aug 28; 4(11):a017376. PMID: 25167981.
      Citations: 17     Fields:    Translation:HumansAnimals
    48. Mitra RN, Merwin MJ, Han Z, Conley SM, Al-Ubaidi MR, Naash MI. Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration. Free Radic Biol Med. 2014 Oct; 75:140-8. PMID: 25066531.
      Citations: 22     Fields:    Translation:AnimalsCellsPHPublic Health
    49. Stuck MW, Conley SM, Naash MI. The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse. Hum Mol Genet. 2014 Dec 01; 23(23):6260-74. PMID: 25001182.
      Citations: 34     Fields:    Translation:AnimalsCells
    50. Chakraborty D, Conley SM, Al-Ubaidi MR, Naash MI. Initiation of rod outer segment disc formation requires RDS. PLoS One. 2014; 9(6):e98939. PMID: 24897172.
      Citations: 30     Fields:    Translation:AnimalsCells
    51. Conley SM, Al-Ubaidi MR, Han Z, Naash MI. Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins. FASEB J. 2014 Aug; 28(8):3468-79. PMID: 24736412.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    52. Conley SM, Stuck MW, Burnett JL, Chakraborty D, Azadi S, Fliesler SJ, Naash MI. Insights into the mechanisms of macular degeneration associated with the R172W mutation in RDS. Hum Mol Genet. 2014 Jun 15; 23(12):3102-14. PMID: 24463884.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    53. Stuck MW, Conley SM, Shaw RA, Wolf R, Naash MI. Electrophysiological characterization of rod and cone responses in the baboon nonhuman primate model. Adv Exp Med Biol. 2014; 801:67-73. PMID: 24664682.
      Citations:    Fields:    Translation:HumansAnimalsCells
    54. Koirala A, Conley SM, Naash MI. Episomal maintenance of S/MAR-containing non-viral vectors for RPE-based diseases. Adv Exp Med Biol. 2014; 801:703-9. PMID: 24664761.
      Citations: 12     Fields:    Translation:AnimalsCells
    55. Han Z, Conley SM, Naash MI. Gene therapy for Stargardt disease associated with ABCA4 gene. Adv Exp Med Biol. 2014; 801:719-24. PMID: 24664763.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    56. Al-Ubaidi MR, Naash MI, Conley SM. A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders. Invest Ophthalmol Vis Sci. 2013 Dec 17; 54(13):8119-24. PMID: 24346621.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    57. Mitra RN, Han Z, Merwin M, Al Taai M, Conley SM, Naash MI. Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery. ChemMedChem. 2014 Jan; 9(1):189-96. PMID: 24203490.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    58. Koirala A, Conley SM, Makkia R, Liu Z, Cooper MJ, Sparrow JR, Naash MI. Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases. J Control Release. 2013 Dec 28; 172(3):745-52. PMID: 24035979.
      Citations: 26     Fields:    Translation:HumansAnimals
    59. Koirala A, Conley SM, Naash MI. A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium. Biomaterials. 2013 Sep; 34(29):7158-67. PMID: 23796578.
      Citations: 21     Fields:    Translation:HumansAnimals
    60. Chakraborty D, Conley SM, Naash MI. Overexpression of retinal degeneration slow (RDS) protein adversely affects rods in the rd7 model of enhanced S-cone syndrome. PLoS One. 2013; 8(5):e63321. PMID: 23650562.
      Citations: 1     Fields:    Translation:AnimalsCells
    61. Koirala A, Makkia RS, Conley SM, Cooper MJ, Naash MI. S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA. Hum Mol Genet. 2013 Apr 15; 22(8):1632-42. PMID: 23335596.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    62. Han Z, Guo J, Conley SM, Naash MI. Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2013 Jan 17; 54(1):574-84. PMID: 23221078.
      Citations: 53     Fields:    Translation:Animals
    63. Han Z, Conley SM, Makkia R, Guo J, Cooper MJ, Naash MI. Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery. PLoS One. 2012; 7(12):e52189. PMID: 23272225.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    64. Chakraborty D, Rodgers KK, Conley SM, Naash MI. Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS. FEBS J. 2013 Jan; 280(1):127-38. PMID: 23121719.
      Citations: 5     Fields:    Translation:AnimalsCells
    65. Maxwell E, Tan Y, Tan Y, Hu H, Benson G, Aizikov K, Conley S, Staples GO, Slysz GW, Smith RD, Zaia J. GlycReSoft: a software package for automated recognition of glycans from LC/MS data. PLoS One. 2012; 7(9):e45474. PMID: 23049804.
      Citations: 69     Fields:    Translation:AnimalsCells
    66. Han Z, Conley SM, Makkia RS, Cooper MJ, Naash MI. DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice. J Clin Invest. 2012 Sep; 122(9):3221-6. PMID: 22886305.
      Citations: 78     Fields:    Translation:HumansAnimals
    67. Vuong L, Conley SM, Al-Ubaidi MR. Expression and role of p53 in the retina. Invest Ophthalmol Vis Sci. 2012 Mar 15; 53(3):1362-71. PMID: 22427613.
      Citations: 17     Fields:    Translation:HumansAnimals
    68. Stuck MW, Conley SM, Naash MI. Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina. PLoS One. 2012; 7(3):e32484. PMID: 22427845.
      Citations: 32     Fields:    Translation:AnimalsCells
    69. Chakraborty D, Conley SM, Nash Z, Ding XQ, Naash MI. Overexpression of ROM-1 in the cone-dominant retina. Adv Exp Med Biol. 2012; 723:633-9. PMID: 22183387.
      Citations: 6     Fields:    Translation:AnimalsCells
    70. Conley SM, Chakraborty D, Naash MI. Mislocalization of oligomerization-incompetent RDS is associated with mislocalization of cone opsins and cone transducin. Adv Exp Med Biol. 2012; 723:657-62. PMID: 22183390.
      Citations: 3     Fields:    Translation:AnimalsCells
    71. Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. Biochim Biophys Acta. 2012 Jul; 1822(7):1169-79. PMID: 22033104.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    72. Conley SM, Stuck MW, Naash MI. Structural and functional relationships between photoreceptor tetraspanins and other superfamily members. Cell Mol Life Sci. 2012 Apr; 69(7):1035-47. PMID: 21655915.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    73. Han Z, Conley SM, Naash MI. AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects. Invest Ophthalmol Vis Sci. 2011 May 10; 52(6):3051-9. PMID: 21558483.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    74. Chakraborty D, Conley SM, Stuck MW, Naash MI. Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDS. Hum Mol Genet. 2010 Dec 15; 19(24):4799-812. PMID: 20858597.
      Citations: 36     Fields:    Translation:AnimalsCells
    75. Conley SM, Naash MI. Nanoparticles for retinal gene therapy. Prog Retin Eye Res. 2010 Sep; 29(5):376-97. PMID: 20452457.
      Citations: 36     Fields:    Translation:Humans
    76. Cai X, Conley SM, Cheng T, Al-Ubaidi MR, Naash MI. A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression. Exp Eye Res. 2010 Aug; 91(2):186-94. PMID: 20447394.
      Citations: 5     Fields:    Translation:AnimalsCells
    77. Conley SM, Stricker HM, Naash MI. Biochemical analysis of phenotypic diversity associated with mutations in codon 244 of the retinal degeneration slow gene. Biochemistry. 2010 Feb 09; 49(5):905-11. PMID: 20055437.
      Citations: 21     Fields:    Translation:AnimalsCells
    78. Chakraborty D, Conley SM, Fliesler SJ, Naash MI. The function of oligomerization-incompetent RDS in rods. Adv Exp Med Biol. 2010; 664:39-46. PMID: 20238000.
      Citations: 5     Fields:    Translation:AnimalsCells
    79. Conley SM, Ding XQ, Naash MI. RDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel. Adv Exp Med Biol. 2010; 664:63-70. PMID: 20238003.
      Citations: 7     Fields:    Translation:AnimalsCells
    80. Cai X, Conley SM, Naash MI. Gene therapy in the Retinal Degeneration Slow model of retinitis pigmentosa. Adv Exp Med Biol. 2010; 664:611-9. PMID: 20238065.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    81. Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. FASEB J. 2010 Apr; 24(4):1178-91. PMID: 19952284.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    82. Ding XQ, Quiambao AB, Fitzgerald JB, Cooper MJ, Conley SM, Naash MI. Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. PLoS One. 2009 Oct 12; 4(10):e7410. PMID: 19823583.
      Citations: 42     Fields:    Translation:Animals
    83. Cai X, Conley SM, Naash MI. RPE65: role in the visual cycle, human retinal disease, and gene therapy. Ophthalmic Genet. 2009 Jun; 30(2):57-62. PMID: 19373675.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    84. Cai X, Nash Z, Conley SM, Fliesler SJ, Cooper MJ, Naash MI. A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles. PLoS One. 2009; 4(4):e5290. PMID: 19390689.
      Citations: 63     Fields:    Translation:AnimalsCells
    85. Conley SM, Naash MI. Focus on molecules: RDS. Exp Eye Res. 2009 Sep; 89(3):278-9. PMID: 19366620.
      Citations: 6     Fields:    Translation:Humans
    86. Chakraborty D, Ding XQ, Conley SM, Fliesler SJ, Naash MI. Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones. Hum Mol Genet. 2009 Mar 01; 18(5):797-808. PMID: 19050038.
      Citations: 46     Fields:    Translation:AnimalsCells
    87. Conley SM, Cai X, Naash MI. Nonviral ocular gene therapy: assessment and future directions. Curr Opin Mol Ther. 2008 Oct; 10(5):456-63. PMID: 18830921.
      Citations: 23     Fields:    Translation:HumansAnimals
    88. Stamer WD, Chan DW, Conley SM, Coons S, Ethier CR. Aquaporin-1 expression and conventional aqueous outflow in human eyes. Exp Eye Res. 2008 Oct; 87(4):349-55. PMID: 18657536.
      Citations: 7     Fields:    Translation:HumansCells
    89. Conley S, Nour M, Fliesler SJ, Naash MI. Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5397-407. PMID: 18055786.
      Citations: 14     Fields:    Translation:AnimalsCells
    90. Cai X, Conley S, Naash M. Nanoparticle applications in ocular gene therapy. Vision Res. 2008 Feb; 48(3):319-24. PMID: 17825344.
      Citations: 33     Fields:    Translation:Humans
    91. Conley SM, McKay BS, Gandolfi AJ, Stamer WD. Alterations in human trabecular meshwork cell homeostasis by selenium. Exp Eye Res. 2006 Apr; 82(4):637-47. PMID: 16289047.
      Citations: 3     Fields:    Translation:HumansCells
    92. Hoffman EA, Conley SM, Stamer WD, McKay BS. Barriers to productive transfection of trabecular meshwork cells. Mol Vis. 2005 Oct 26; 11:869-75. PMID: 16270026.
      Citations: 2     Fields:    Translation:HumansCells
    93. Burgess JL, Fierro MA, Lantz RC, Hysong TA, Fleming JE, Gerkin R, Hnizdo E, Conley SM, Klimecki W. Longitudinal decline in lung function: evaluation of interleukin-10 genetic polymorphisms in firefighters. J Occup Environ Med. 2004 Oct; 46(10):1013-22. PMID: 15602175.
      Citations: 9     Fields:    Translation:HumansCells
    94. Conley SM, Bruhn RL, Morgan PV, Stamer WD. Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2004 Feb; 45(2):473-9. PMID: 14744887.
      Citations: 5     Fields:    Translation:HumansCells
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