"Naloxone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
| Descriptor ID |
D009270
|
| MeSH Number(s) |
D03.132.577.249.706 D03.605.497.750 D03.633.400.686.750 D04.615.723.795.706
|
| Concept/Terms |
MRZ-2593- MRZ-2593
- MRZ 2593
- MRZ2593
- MRZ 2593-Br
- MRZ 2593 Br
- MRZ 2593Br
|
Below are MeSH descriptors whose meaning is more general than "Naloxone".
Below are MeSH descriptors whose meaning is more specific than "Naloxone".
This graph shows the total number of publications written about "Naloxone" by people in this website by year, and whether "Naloxone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Naloxone" by people in Profiles.
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Williams K, Lang ES, Panchal AR, Gasper JJ, Taillac P, Gouda J, Lyng JW, Goodloe JM, Hedges M. Evidence-Based Guidelines for EMS Administration of Naloxone. Prehosp Emerg Care. 2019 Nov-Dec; 23(6):749-763.
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Goodloe JM, Dailey MW, Heightman AJ. Armed with naloxone. JEMS. 2014 Aug; 39(8):28-33.
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Goodloe JM. Not so fast on naloxone? There's growing support for non-paramedic use, but keep these cautions in mind. EMS World. 2014 May; 43(5):51-2.
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Patkar KA, Wu J, Ganno ML, Singh HD, Ross NC, Rasakham K, Toll L, McLaughlin JP. Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on ?-opioid receptors. J Pharmacol Exp Ther. 2013 Sep; 346(3):545-54.
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Miller JL, Hagemann TM. Use of pure opioid antagonists for management of opioid-induced pruritus. Am J Health Syst Pharm. 2011 Aug 01; 68(15):1419-25.
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Darnell CM, Thompson J, Stromberg D, Roy L, Sheeran P. Effect of low-dose naloxone infusion on fentanyl requirements in critically ill children. Pediatrics. 2008 May; 121(5):e1363-71.
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Sharpe AL, Samson HH. Effect of naloxone on appetitive and consummatory phases of ethanol self-administration. Alcohol Clin Exp Res. 2001 Jul; 25(7):1006-11.
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Mathis JP, Mandyam CD, Altememi GF, Pasternak GW, Standifer KM. Orphanin FQ/nociceptin and naloxone benzoylhydrazone activate distinct receptors in BE(2)-C human neuroblastoma cells. Neurosci Lett. 2001 Feb 23; 299(3):173-6.
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Ryan-Moro J, Chien CC, Standifer KM, Pasternak GW. Sigma binding in a human neuroblastoma cell line. Neurochem Res. 1996 Nov; 21(11):1309-14.
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Ciszewska GR, Ginos JA, Charton M, Standifer KM, Brooks AI, Brown GP, Ryan-Moro JP, Berzetei-Gurske I, Toll L, Pasternak GW. Synthesis and characterization of substituted benzoylhydrazones of naloxone. Synapse. 1996 Oct; 24(2):193-201.