Methylenetetrahydrofolate Dehydrogenase (NADP)
"Methylenetetrahydrofolate Dehydrogenase (NADP)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher eukaryotes a trifunctional enzyme exists with additional METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE and FORMATE-TETRAHYDROFOLATE LIGASE activity. The enzyme plays an important role in the synthesis of 5-methyltetrahydrofolate, the methyl donor for the VITAMIN B12-dependent remethylation of HOMOCYSTEINE to METHIONINE via METHIONINE SYNTHETASE.
| Descriptor ID |
D008754
|
| MeSH Number(s) |
D08.811.682.662.253
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylenetetrahydrofolate Dehydrogenase (NADP)".
Below are MeSH descriptors whose meaning is more specific than "Methylenetetrahydrofolate Dehydrogenase (NADP)".
This graph shows the total number of publications written about "Methylenetetrahydrofolate Dehydrogenase (NADP)" by people in this website by year, and whether "Methylenetetrahydrofolate Dehydrogenase (NADP)" was a major or minor topic of these publications.
![]()
To see the data from this visualization as text,
click here.
Below are the most recent publications written about "Methylenetetrahydrofolate Dehydrogenase (NADP)" by people in Profiles.
-
Tetrahydrofolate enzyme levels in Acetobacterium woodii and their implication in the synthesis of acetate from CO2. J Bacteriol. 1978 May; 134(2):668-70.