Platelet-Derived Growth Factor
"Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
| Descriptor ID |
D010982
|
| MeSH Number(s) |
D12.644.276.910 D12.776.124.625 D12.776.467.910 D23.529.910
|
| Concept/Terms |
Platelet-Derived Growth Factor- Platelet-Derived Growth Factor
- Factor, Platelet-Derived Growth
- Growth Factor, Platelet-Derived
- Platelet Derived Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Platelet-Derived Growth Factor" by people in this website by year, and whether "Platelet-Derived Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 1 | 3 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Platelet-Derived Growth Factor" by people in Profiles.
-
Platelet-Rich Plasma Injections: Pharmacological and Clinical Considerations in Pain Management. Curr Pain Headache Rep. 2022 Oct; 26(10):741-749.
-
Temporal control of PDGFRa regulates the fibroblast-to-myofibroblast transition in wound healing. Cell Rep. 2022 08 16; 40(7):111192.
-
Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer. Adv Drug Deliv Rev. 2021 11; 178:113918.
-
Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities. Curr Rheumatol Rep. 2013 Feb; 15(2):304.
-
TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. Am J Physiol Cell Physiol. 2010 Jan; 298(1):C191-201.
-
Prognostic significance of CD44, platelet-derived growth factor receptor alpha, and cyclooxygenase 2 expression in renal cell carcinoma. Arch Pathol Lab Med. 2007 Feb; 131(2):261-7.
-
Matrix metalloproteinase-2 expression by vascular smooth muscle cells is mediated by both stimulatory and inhibitory signals in response to growth factors. J Biol Chem. 2006 Sep 08; 281(36):25915-25.
-
Effect of rhPDGF-BB delivery on mediators of periodontal wound repair. Tissue Eng. 2006 Jun; 12(6):1441-50.
-
Effect of rhPDGF-BB on bone turnover during periodontal repair. J Clin Periodontol. 2006 Feb; 33(2):135-40.
-
Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2006 Feb; 290(2):C352-61.