"Protein S" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.
Descriptor ID |
D017293
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MeSH Number(s) |
D12.776.124.670 D12.776.395.642 D23.113.725
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Concept/Terms |
Protein S- Protein S
- Vitamin K-Dependent Protein S
- Vitamin K Dependent Protein S
- Cofactor Protein S
- Protein S, Cofactor
- Protein S, Vitamin K-Dependent
- Protein S, Vitamin K Dependent
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Below are MeSH descriptors whose meaning is more general than "Protein S".
Below are MeSH descriptors whose meaning is more specific than "Protein S".
This graph shows the total number of publications written about "Protein S" by people in this website by year, and whether "Protein S" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein S" by people in Profiles.
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Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling. Int J Mol Sci. 2019 Mar 07; 20(5).
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TAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus. Arthritis Res Ther. 2010; 12(4):R146.
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Antibodies directed to protein S in patients with systemic lupus erythematosus: prevalence and clinical significance. Thromb Haemost. 2003 Oct; 90(4):636-41.
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Dual antibody reactivity to beta2-glycoprotein I and protein S: increased association with thrombotic events in the antiphospholipid syndrome. Lupus. 2002; 11(4):215-20.
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An association between plasma free protein s concentration and risk of coronary heart disease in middle-aged men. Thromb Res. 2001 Jan 15; 101(2):1-11.
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Sex hormone binding globulins and atherosclerotic risk in systemic lupus. Lupus. 2000; 9(3):217-22.
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Enhancement of protein S anticoagulant function by beta2-glycoprotein I, a major target antigen of antiphospholipid antibodies: beta2-glycoprotein I interferes with binding of protein S to its plasma inhibitor, C4b-binding protein. Thromb Haemost. 1999 May; 81(5):748-57.
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Cytokine-induced alteration of platelet and hemostatic function. Stem Cells. 1996; 14 Suppl 1:154-62.
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Recent advances in understanding clotting and evaluating patients with recurrent thrombosis. Am J Obstet Gynecol. 1992 Oct; 167(4 Pt 2):1184-91.
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A 5.3-kb deletion including exon XIII of the protein S alpha gene occurs in two protein S-deficient families. Blood. 1991 Feb 01; 77(3):551-9.