"alpha 1-Antichymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.
| Descriptor ID |
D000514
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| MeSH Number(s) |
D12.644.861.030 D12.776.124.050.050 D12.776.124.790.106.050 D12.776.377.715.085.050 D12.776.395.045 D12.776.872.030
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "alpha 1-Antichymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "alpha 1-Antichymotrypsin".
This graph shows the total number of publications written about "alpha 1-Antichymotrypsin" by people in this website by year, and whether "alpha 1-Antichymotrypsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha 1-Antichymotrypsin" by people in Profiles.
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Association between ACT polymorphism and Alzheimer's disease. Neurology. 1998 Feb; 50(2):574-6.
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Re: Genetic effect of alpha 1-antichymotrypsin on the risk of Alzheimer disease. Genomics. 1997 Mar 01; 40(2):382-5.
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Gender-specific nonrandom association between the alpha 1-antichymotrypsin and apolipoprotein E polymorphisms in the general population and its implication for the risk of Alzheimer's disease. Genet Epidemiol. 1997; 14(2):169-80.
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Polygenic determinants of Alzheimer's disease: modulation of the risk by alpha-1-antichymotrypsin. Ann N Y Acad Sci. 1996 Dec 16; 802:27-34.
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APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism. Nat Genet. 1995 Aug; 10(4):486-8.