"Mitochondria, Liver" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
| Descriptor ID |
D008930
|
| MeSH Number(s) |
A11.284.430.214.190.875.564.461 A11.284.835.626.461
|
| Concept/Terms |
Mitochondria, Liver- Mitochondria, Liver
- Liver Mitochondria
- Liver Mitochondrion
- Mitochondrion, Liver
|
Below are MeSH descriptors whose meaning is more general than "Mitochondria, Liver".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria, Liver".
This graph shows the total number of publications written about "Mitochondria, Liver" by people in this website by year, and whether "Mitochondria, Liver" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitochondria, Liver" by people in Profiles.
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Baker PR, Friedman JE. Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease. J Clin Invest. 2018 08 31; 128(9):3692-3703.
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Das N, Mandala A, Naaz S, Giri S, Jain M, Bandyopadhyay D, Reiter RJ, Roy SS. Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice. J Pineal Res. 2017 May; 62(4).
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Rahman SM, Choudhury M, Janssen RC, Baquero KC, Miyazaki M, Friedman JE. CCAAT/enhancer binding protein ß deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis. Biochem Biophys Res Commun. 2013 Jan 04; 430(1):336-9.
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Griesel BA, Weems J, Russell RA, Abel ED, Humphries K, Olson AL. Acute inhibition of fatty acid import inhibits GLUT4 transcription in adipose tissue, but not skeletal or cardiac muscle tissue, partly through liver X receptor (LXR) signaling. Diabetes. 2010 Apr; 59(4):800-7.
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Short KR. Mitochondrial ATP measurements. Am J Physiol Regul Integr Comp Physiol. 2004 Jul; 287(1):R243-5; author reply R245-6.
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Kantrow SP, Gierman JL, Jaligam VR, Zhang P, Piantadosi CA, Summer WR, Lancaster JR. Regulation of tumor necrosis factor cytotoxicity by calcineurin. FEBS Lett. 2000 Oct 20; 483(2-3):119-24.
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Reinke LA, Tupper JS, Sweeny DJ. 7-ethoxycoumarin O-deethylation in perfused livers from ethanol-fed rats: evidence for an important role of mitochondrial reducing equivalents. Pharmacology. 1987; 34(2-3):167-75.
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Reinke LA, Kauffman FC, Belinsky SA, Thurman RG. Effects of ethanol and sorbitol on mixed-function oxidation in perfused rat livers. Pharmacol Biochem Behav. 1983; 18 Suppl 1:289-94.
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Reinke LA, Belinsky SA, Kauffman FC, Evans RK, Thurman RG. Regulation of NADPH-dependent mixed-function oxidation in perfused livers. Comparative studies with sorbitol and ethanol. Biochem Pharmacol. 1982 Apr 15; 31(8):1621-8.