Header Logo

Rachel C Janssen

TitleLab Rsrch Asoc Dir
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentHarold Hamm Diabetes Ctr
AddressBRC 362
975 NE 10th St
Oklahoma City OK 73104
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sugino KY, Janssen RC, McMahan RH, Zimmerman C, Friedman JE, Jonscher KR. Vertical Transfer of Maternal Gut Microbes to Offspring of Western Diet-Fed Dams Drives Reduced Levels of Tryptophan Metabolites and Postnatal Innate Immune Response. Nutrients. 2024 Jun 08; 16(12). PMID: 38931163; PMCID: PMC11206590.
      Citations: 1     Fields:    Translation:AnimalsCells
    2. Nash MJ, Dobrinskikh E, Wang D, Pietras EM, Janssen RC, Friedman JE, Wesolowski SR. Isolating mononuclear cells from fetal bone and liver for metabolic, functional, and immunophenotypic analyses in nonhuman primates. STAR Protoc. 2024 Feb 06; 5(1):102849. PMID: 38324447; PMCID: PMC10859273.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Perng W, Salmon K, Schenker R, Janssen RC, Friedman JE, Goran MI. Endotoxin biomarkers, hepatic fat fraction, liver volume and liver stiffness among adolescents at high-risk for non-alcoholic fatty liver disease: The HEROES study. Pediatr Obes. 2023 Dec 12; e13091. PMID: 38084670.
      Citations:    Fields:    Translation:Humans
    4. Nash MJ, Dobrinskikh E, Soderborg TK, Janssen RC, Takahashi DL, Dean TA, Varlamov O, Hennebold JD, Gannon M, Aagaard KM, McCurdy CE, Kievit P, Bergman BC, Jones KL, Pietras EM, Wesolowski SR, Friedman JE. Maternal diet?alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring. Cell Rep. 2023 Apr 13; 42(4):112393. PMID: 37058409.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    5. Nash MJ, Dobrinskikh E, Janssen RC, Lovell MA, Schady DA, Levek C, Jones KL, D'Alessandro A, Kievit P, Aagaard KM, McCurdy CE, Gannon M, Friedman JE, Wesolowski SR. Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring. Hepatol Commun. 2023 Feb 01; 7(2):e0014. PMID: 36691970; PMCID: PMC9851700.
      Citations: 4     Fields:    Translation:Animals
    6. Sugino KY, Mandala A, Janssen RC, Gurung S, Trammell M, Day MW, Brush RS, Papin JF, Dyer DW, Agbaga MP, Friedman JE, Castillo-Castrejon M, Jonscher KR, Myers DA. Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver. Front Clin Diabetes Healthc. 2022; 3. PMID: 36935840; PMCID: PMC10012127.
      Citations: 4     
    7. Perng W, Friedman JE, Janssen RC, Glueck DH, Dabelea D. Endotoxin Biomarkers Are Associated With Adiposity and Cardiometabolic Risk Across 6 Years of Follow-up in Youth. J Clin Endocrinol Metab. 2022 06 16; 107(7):e3018-e3028. PMID: 35276001.
      Citations: 3     Fields:    Translation:Humans
    8. Mandala A, Dobrinskikh E, Janssen RC, Fiehn O, D'Alessandro A, Friedman JE, Jonscher KR. Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD. Int J Mol Sci. 2022 May 27; 23(11). PMID: 35682720.
      Citations: 3     Fields:    Translation:HumansAnimals
    9. Nash MJ, Dobrinskikh E, Newsom SA, Messaoudi I, Janssen RC, Aagaard KM, McCurdy CE, Gannon M, Kievit P, Friedman JE, Wesolowski SR. Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring. JCI Insight. 2021 12 22; 6(24). PMID: 34935645.
      Citations: 9     Fields:    Translation:AnimalsPHPublic Health
    10. Soderborg TK, Carpenter CM, Janssen RC, Weir TL, Robertson CE, Ir D, Young BE, Krebs NF, Hernandez TL, Barbour LA, Frank DN, Kroehl M, Friedman JE. Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota. Front Endocrinol (Lausanne). 2020; 11:603021. PMID: 33329403.
      Citations: 34     Fields:    Translation:HumansCells
    11. Mandala A, Janssen RC, Palle S, Short KR, Friedman JE. Pediatric Non-Alcoholic Fatty Liver Disease: Nutritional Origins and Potential Molecular Mechanisms. Nutrients. 2020 Oct 16; 12(10). PMID: 33081177.
      Citations: 21     Fields:    Translation:HumansCells
    12. Boyle KE, Magill-Collins MJ, Newsom SA, Janssen RC, Friedman JE. Maternal Fat-1 Transgene Protects Offspring from Excess Weight Gain, Oxidative Stress, and Reduced Fatty Acid Oxidation in Response to High-Fat Diet. Nutrients. 2020 Mar 14; 12(3). PMID: 32183350.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    13. Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Young B, Krebs NF, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE. Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2019 Jul 01; 10(1):2965. PMID: 31263097.
      Citations: 1     Fields:    
    14. Janssen RC, Boyle KE. Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity. Methods Mol Biol. 2019; 1978:355-368. PMID: 31119674.
      Citations: 10     Fields:    Translation:Cells
    15. Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Young B, Krebs N, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018 10 26; 9(1):4462. PMID: 30367045.
      Citations: 118     Fields:    Translation:HumansAnimals
    16. Wesolowski SR, Mulligan CM, Janssen RC, Baker PR, Bergman BC, D'Alessandro A, Nemkov T, Maclean KN, Jiang H, Dean TA, Takahashi DL, Kievit P, McCurdy CE, Aagaard KM, Friedman JE. Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates. Mol Metab. 2018 12; 18:25-41. PMID: 30337225.
      Citations: 26     Fields:    Translation:AnimalsCells
    17. Heerwagen MJR, Gumina DL, Hernandez TL, Van Pelt RE, Kramer AW, Janssen RC, Jensen DR, Powell TL, Friedman JE, Winn VD, Barbour LA. Placental lipoprotein lipase activity is positively associated with newborn adiposity. Placenta. 2018 04; 64:53-60. PMID: 29626981.
      Citations: 25     Fields:    Translation:Humans
    18. Friedman JE, Dobrinskikh E, Alfonso-Garcia A, Fast A, Janssen RC, Soderborg TK, Anderson AL, Reisz JA, D'Alessandro A, Frank DN, Robertson CE, de la Houssaye BA, Johnson LK, Orlicky DJ, Wang XX, Levi M, Potma EO, El Kasmi KC, Jonscher KR. Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice. Hepatol Commun. 2018 03; 2(3):313-328. PMID: 29507905.
      Citations: 25     Fields:    
    19. Baker PR, Patinkin ZW, Shapiro ALB, de la Houssaye BA, Janssen RC, Vanderlinden LA, Dabelea D, Friedman JE. Altered gene expression and metabolism in fetal umbilical cord mesenchymal stem cells correspond with differences in 5-month-old infant adiposity gain. Sci Rep. 2017 12 22; 7(1):18095. PMID: 29273781.
      Citations: 14     Fields:    Translation:HumansCells
    20. Boyle KE, Patinkin ZW, Shapiro ALB, Bader C, Vanderlinden L, Kechris K, Janssen RC, Ford RJ, Smith BK, Steinberg GR, Davidson EJ, Yang IV, Dabelea D, Friedman JE. Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants. Mol Metab. 2017 11; 6(11):1503-1516. PMID: 29107296.
      Citations: 33     Fields:    Translation:HumansCells
    21. Jonscher KR, Stewart MS, Alfonso-Garcia A, DeFelice BC, Wang XX, Luo Y, Levi M, Heerwagen MJ, Janssen RC, de la Houssaye BA, Wiitala E, Florey G, Jonscher RL, Potma EO, Fiehn O, Friedman JE. Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice. FASEB J. 2017 04; 31(4):1434-1448. PMID: 28007783.
      Citations: 31     Fields:    Translation:Animals
    22. Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2017 Jan; 49(1):50-57. PMID: 28103623.
      Citations: 7     Fields:    Translation:HumansCells
    23. Rahman SM, Baquero KC, Choudhury M, Janssen RC, de la Houssaye BA, Sun M, Miyazaki-Anzai S, Wang S, Moustaid-Moussa N, Miyazaki M, Friedman JE. C/EBPß in bone marrow is essential for diet induced inflammation, cholesterol balance, and atherosclerosis. Atherosclerosis. 2016 07; 250:172-9. PMID: 27072340.
      Citations: 12     Fields:    Translation:AnimalsCells
    24. Hernandez TL, Van Pelt RE, Anderson MA, Reece MS, Reynolds RM, de la Houssaye BA, Heerwagen M, Donahoo WT, Daniels LJ, Chartier-Logan C, Janssen RC, Friedman JE, Barbour LA. Women With Gestational Diabetes Mellitus Randomized to a Higher-Complex Carbohydrate/Low-Fat Diet Manifest Lower Adipose Tissue Insulin Resistance, Inflammation, Glucose, and Free Fatty Acids: A Pilot Study. Diabetes Care. 2016 Jan; 39(1):39-42. PMID: 26223240.
      Citations: 66     Fields:    Translation:HumansPHPublic Health
    25. Boyle KE, Hwang H, Janssen RC, DeVente JM, Barbour LA, Hernandez TL, Mandarino LJ, Lappas M, Friedman JE. Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. PLoS One. 2014; 9(9):e106872. PMID: 25216282.
      Citations: 25     Fields:    Translation:HumansCells
    26. Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE. Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):E1601-9. PMID: 23956348.
      Citations: 31     Fields:    Translation:HumansCells
    27. Heerwagen MJ, Stewart MS, de la Houssaye BA, Janssen RC, Friedman JE. Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice. PLoS One. 2013; 8(6):e67791. PMID: 23825686.
      Citations: 56     Fields:    Translation:HumansAnimals
    28. Rahman SM, Choudhury M, Janssen RC, Baquero KC, Miyazaki M, Friedman JE. CCAAT/enhancer binding protein ß deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis. Biochem Biophys Res Commun. 2013 Jan 04; 430(1):336-9. PMID: 23159614.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Qadri I, Choudhury M, Rahman SM, Knotts TA, Janssen RC, Schaack J, Iwahashi M, Puljak L, Simon FR, Kilic G, Fitz JG, Friedman JE. Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein ß. J Biol Chem. 2012 Oct 26; 287(44):37340-51. PMID: 22955269.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    30. Rahman SM, Janssen RC, Choudhury M, Baquero KC, Aikens RM, de la Houssaye BA, Friedman JE. CCAAT/enhancer-binding protein ß (C/EBPß) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem. 2012 Oct 05; 287(41):34349-60. PMID: 22902781.
      Citations: 60     Fields:    Translation:AnimalsCells
    31. Attia RR, Sharma P, Janssen RC, Friedman JE, Deng X, Lee JS, Elam MB, Cook GA, Park EA. Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by CCAAT/enhancer-binding protein beta (C/EBPbeta). J Biol Chem. 2011 Jul 08; 286(27):23799-807. PMID: 21586575.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    32. Choudhury M, Qadri I, Rahman SM, Schroeder-Gloeckler J, Janssen RC, Friedman JE. C/EBPß is AMP kinase sensitive and up-regulates PEPCK in response to ER stress in hepatoma cells. Mol Cell Endocrinol. 2011 Jan 01; 331(1):102-8. PMID: 20797423.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    33. Majka SM, Fox KE, Psilas JC, Helm KM, Childs CR, Acosta AS, Janssen RC, Friedman JE, Woessner BT, Shade TR, Varella-Garcia M, Klemm DJ. De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14781-6. PMID: 20679227.
      Citations: 78     Fields:    Translation:AnimalsCells
    34. Moriarty MW, McCurdy CE, Janssen RC, Shaw T, Leitner JW, Friedman JE, Draznin B. In vivo knockdown of p85alpha with an antisense oligonucleotide improves insulin sensitivity in Lep(ob/ob) and diet-induced obese mice. Horm Metab Res. 2009 Oct; 41(10):757-61. PMID: 19598077.
      Citations: 1     Fields:    Translation:Animals
    35. Rahman SM, Qadri I, Janssen RC, Friedman JE. Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res. 2009 Nov; 50(11):2193-202. PMID: 19502591.
      Citations: 17     Fields:    Translation:HumansCells
    36. Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH. Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. Diabetes. 2009 Jan; 58(1):116-24. PMID: 18952837.
      Citations: 60     Fields:    Translation:AnimalsCells
    37. Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis. Hepatology. 2007 May; 45(5):1108-17. PMID: 17464987.
      Citations: 65     Fields:    Translation:AnimalsCells
    38. Schroeder-Gloeckler JM, Rahman SM, Janssen RC, Qiao L, Shao J, Roper M, Fischer SJ, Lowe E, Orlicky DJ, McManaman JL, Palmer C, Gitomer WL, Huang W, O'Doherty RM, Becker TC, Klemm DJ, Jensen DR, Pulawa LK, Eckel RH, Friedman JE. CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. J Biol Chem. 2007 May 25; 282(21):15717-29. PMID: 17387171.
      Citations: 55     Fields:    Translation:AnimalsCells
    39. Shao J, Qiao L, Janssen RC, Pagliassotti M, Friedman JE. Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio. Diabetes. 2005 Apr; 54(4):976-84. PMID: 15793235.
      Citations: 25     Fields:    Translation:AnimalsCells
    Janssen's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (262)
    Explore
    _
    Co-Authors (13)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _