Phosphoenolpyruvate Carboxykinase (GTP)
"Phosphoenolpyruvate Carboxykinase (GTP)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
| Descriptor ID |
D010729
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| MeSH Number(s) |
D08.811.520.224.125.550
|
| Concept/Terms |
Phosphoenolpyruvate Carboxykinase (GTP)- Phosphoenolpyruvate Carboxykinase (GTP)
- GTP-Dependent Phosphoenolpyruvate Carboxykinase
- Carboxykinase, GTP-Dependent Phosphoenolpyruvate
- GTP Dependent Phosphoenolpyruvate Carboxykinase
- Phosphoenolpyruvate Carboxykinase, GTP-Dependent
|
Below are MeSH descriptors whose meaning is more general than "Phosphoenolpyruvate Carboxykinase (GTP)".
Below are MeSH descriptors whose meaning is more specific than "Phosphoenolpyruvate Carboxykinase (GTP)".
This graph shows the total number of publications written about "Phosphoenolpyruvate Carboxykinase (GTP)" by people in this website by year, and whether "Phosphoenolpyruvate Carboxykinase (GTP)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphoenolpyruvate Carboxykinase (GTP)" by people in Profiles.
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Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells. FEBS J. 2021 12; 288(23):6683-6699.
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Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein ß. J Biol Chem. 2012 Oct 26; 287(44):37340-51.
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Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology. 2009 Jul; 150(7):3021-30.
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Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio. Diabetes. 2005 Apr; 54(4):976-84.
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Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice. Infect Immun. 1992 Oct; 60(10):4040-50.
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Human recombinant IL-1 alters glucocorticoid receptor function in Reuber hepatoma cells. J Immunol. 1988 Sep 01; 141(5):1522-8.