"RNA Polymerase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
| Descriptor ID |
D012318
|
| MeSH Number(s) |
D08.811.913.696.445.735.270.750
|
| Concept/Terms |
RNA Polymerase I- RNA Polymerase I
- Polymerase I, RNA
- DNA-Dependent RNA Polymerase I
- DNA Dependent RNA Polymerase I
- RNA Polymerase A
- Polymerase A, RNA
|
Below are MeSH descriptors whose meaning is more general than "RNA Polymerase I".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase I".
This graph shows the total number of publications written about "RNA Polymerase I" by people in this website by year, and whether "RNA Polymerase I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 2 | 1 | 3 |
| 1996 | 1 | 3 | 4 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 2 | 2 | 4 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Polymerase I" by people in Profiles.
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The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same. Genes (Basel). 2021 04 22; 12(5).
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Dynamics of the RNA polymerase I TFIIF/TFIIE-like subcomplex: a mini-review. Biochem Soc Trans. 2020 10 30; 48(5):1917-1927.
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Conditional depletion of the RNA polymerase I subunit PAF53 reveals that it is essential for mitosis and enables identification of functional domains. J Biol Chem. 2019 12 27; 294(52):19907-19922.
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Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription. Gene. 2017 May 15; 612:36-48.
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A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes. Genome Res. 2015 Feb; 25(2):201-12.
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Regulation of the association of the PAF53/PAF49 heterodimer with RNA polymerase I. Gene. 2015 Feb 01; 556(1):61-7.
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Selective inhibition of rDNA transcription by a small-molecule peptide that targets the interface between RNA polymerase I and Rrn3. Mol Cancer Res. 2014 Nov; 12(11):1586-96.
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The HBx protein of hepatitis B virus confers resistance against nucleolar stress and anti-cancer drug-induced p53 expression. FEBS Lett. 2013 May 02; 587(9):1287-92.
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Dysregulation of RNA polymerase I transcription during disease. Biochim Biophys Acta. 2013 Mar-Apr; 1829(3-4):342-60.
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Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49. Biochemistry. 2012 Aug 21; 51(33):6519-26.