Thioredoxin-Disulfide Reductase
"Thioredoxin-Disulfide Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
Descriptor ID |
D013880
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MeSH Number(s) |
D08.811.682.667.750 D12.776.331.971
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Concept/Terms |
Thioredoxin-Disulfide Reductase- Thioredoxin-Disulfide Reductase
- Reductase, Thioredoxin-Disulfide
- Thioredoxin Disulfide Reductase
- Thioredoxin Reductase (NADPH)
- Thioredoxin Reductase
- Reductase, Thioredoxin
- NADP-Thioredoxin Reductase
- NADP Thioredoxin Reductase
- Reductase, NADP-Thioredoxin
- NADPH-Thioredoxin Reductase
- NADPH Thioredoxin Reductase
- Reductase, NADPH-Thioredoxin
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Below are MeSH descriptors whose meaning is more general than "Thioredoxin-Disulfide Reductase".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxin-Disulfide Reductase".
This graph shows the total number of publications written about "Thioredoxin-Disulfide Reductase" by people in this website by year, and whether "Thioredoxin-Disulfide Reductase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 2 | 3 |
2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 1 | 2 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thioredoxin-Disulfide Reductase" by people in Profiles.
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Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages. Life Sci. 2020 Oct 15; 259:118285.
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HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy. Oncotarget. 2016 10 04; 7(40):64820-64835.
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Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2-Related Factor 2 Activation. Am J Respir Cell Mol Biol. 2016 09; 55(3):419-28.
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The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR. J Ind Microbiol Biotechnol. 2015 Jun; 42(6):965-9.
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Thioredoxin-1 redox signaling regulates cell survival in response to hyperoxia. Free Radic Biol Med. 2014 Oct; 75:167-77.
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Thioredoxin reductase inhibition elicits Nrf2-mediated responses in Clara cells: implications for oxidant-induced lung injury. Antioxid Redox Signal. 2012 Nov 15; 17(10):1407-16.
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Thioredoxin-related mechanisms in hyperoxic lung injury in mice. Am J Respir Cell Mol Biol. 2007 Oct; 37(4):405-13.
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Delay of photoreceptor degeneration in tubby mouse by sulforaphane. J Neurochem. 2007 May; 101(4):1041-52.
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Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro. Free Radic Biol Med. 2007 Jun 15; 42(12):1838-50.