"Glutathione Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.
| Descriptor ID |
D005980
|
| MeSH Number(s) |
D08.811.682.667.092
|
| Concept/Terms |
Glutathione Reductase- Glutathione Reductase
- Reductase, Glutathione
- Glutathione-Disulfide Reductase
- Reductase, Glutathione-Disulfide
|
Below are MeSH descriptors whose meaning is more general than "Glutathione Reductase".
Below are MeSH descriptors whose meaning is more specific than "Glutathione Reductase".
This graph shows the total number of publications written about "Glutathione Reductase" by people in this website by year, and whether "Glutathione Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutathione Reductase" by people in Profiles.
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Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice. Redox Biol. 2021 01; 38:101797.
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Tempol prevents post-traumatic stress disorder induced memory impairment. Physiol Behav. 2018 02 01; 184:189-195.
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
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Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps. J Immunol. 2012 Mar 01; 188(5):2316-27.
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Methods for the determination of plasma or tissue glutathione levels. Methods Mol Biol. 2012; 889:315-24.
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Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic (spc-mt)hGR mice. Exp Lung Res. 2011 Apr; 37(3):155-61.
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Glutathione reductase targeted to type II cells does not protect mice from hyperoxic lung injury. Am J Respir Cell Mol Biol. 2008 Dec; 39(6):683-8.
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Thioredoxin-related mechanisms in hyperoxic lung injury in mice. Am J Respir Cell Mol Biol. 2007 Oct; 37(4):405-13.
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Kinetics and mechanism of the oxidation of the glutathione dimer by hypochlorous Acid and catalytic reduction of the chloroamine product by glutathione reductase. Chem Res Toxicol. 2007 Jan; 20(1):79-87.
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Hyperoxia increases hepatic arginase expression and ornithine production in mice. Toxicol Appl Pharmacol. 2006 Aug 15; 215(1):109-17.