CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 2 | 4 |
| 2005 | 2 | 2 | 4 |
| 2006 | 2 | 2 | 4 |
| 2007 | 7 | 1 | 8 |
| 2008 | 3 | 4 | 7 |
| 2009 | 3 | 1 | 4 |
| 2010 | 2 | 6 | 8 |
| 2011 | 3 | 3 | 6 |
| 2012 | 2 | 0 | 2 |
| 2013 | 3 | 2 | 5 |
| 2014 | 3 | 0 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 3 | 5 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature. Ann Rheum Dis. 2022 10; 81(10):1428-1437.
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Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8+ T Cell-Dependent Manner. Front Immunol. 2021; 12:742154.
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CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities. Sci Rep. 2021 02 17; 11(1):4011.
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T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. Nat Commun. 2020 10 26; 11(1):5406.
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Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells. J Immunol. 2020 11 01; 205(9):2479-2488.
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Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. Brain Behav Immun. 2020 07; 87:795-803.
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Hepatitis C virus-specific CD4+ T cell phenotype and function in different infection outcomes. J Clin Invest. 2020 02 03; 130(2):768-773.
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Determinants governing T cell receptor a/ß-chain pairing in repertoire formation of identical twins. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):532-540.
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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency. Cell Rep. 2019 11 19; 29(8):2202-2216.e5.
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Complement and CD4+ T cells drive context-specific corneal sensory neuropathy. Elife. 2019 08 15; 8.