"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
| Descriptor ID |
D015603
|
| MeSH Number(s) |
A11.436.397
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratinocytes".
Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".
This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 3 | 5 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Keratinocytes" by people in Profiles.
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Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds. Commun Biol. 2021 06 18; 4(1):757.
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Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing. Sci Rep. 2020 03 05; 10(1):4123.
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IL-6 Negatively Regulates IL-22Ra Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis. J Immunol Res. 2019; 2019:6276254.
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Keratinocyte-specific deletion of the IL-6R? exacerbates the inflammatory response during irritant contact dermatitis. Toxicology. 2019 07 01; 423:123-131.
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Interleukin 6 Function in the Skin and Isolated Keratinocytes Is Modulated by Hyperglycemia. J Immunol Res. 2019; 2019:5087847.
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Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation. Toxicology. 2018 12 01; 410:1-9.
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Transforming growth factor-ß and psoriasis: a new link. Br J Dermatol. 2017 12; 177(6):1480-1481.
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Interleukin (IL)-6 modulates transforming growth factor-ß receptor I and II (TGF-ßRI and II) function in epidermal keratinocytes. Exp Dermatol. 2017 08; 26(8):697-704.
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Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression. PLoS One. 2016; 11(8):e0160615.
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Vitiligo patient-derived keratinocytes exhibit characteristics of normal wound healing via epithelial to mesenchymal transition. Exp Dermatol. 2015 May; 24(5):391-3.