"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
| Descriptor ID |
D015603
|
| MeSH Number(s) |
A11.436.397
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratinocytes".
Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".
This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 2 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 3 | 0 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Keratinocytes" by people in Profiles.
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Aberrant activation of AXL may drive progression of squamous cell carcinoma in CLL patients: a mechanistic study with clinical implications. Br J Cancer. 2024 Aug; 131(3):589-600.
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The human testis-enriched HSPA2 interacts with HIF-1a in epidermal keratinocytes, yet HIF-1a stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity. Biochim Biophys Acta Mol Cell Res. 2024 Jun; 1871(5):119735.
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Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes. Int J Mol Sci. 2023 May 05; 24(9).
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Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds. Commun Biol. 2021 06 18; 4(1):757.
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Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1a-NF-?B Crosstalk In Vitro and In Vivo. Int J Mol Sci. 2020 Dec 04; 21(23).
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Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing. Sci Rep. 2020 03 05; 10(1):4123.
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IL-6 Negatively Regulates IL-22Ra Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis. J Immunol Res. 2019; 2019:6276254.
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Keratinocyte-specific deletion of the IL-6R? exacerbates the inflammatory response during irritant contact dermatitis. Toxicology. 2019 07 01; 423:123-131.
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Interleukin 6 Function in the Skin and Isolated Keratinocytes Is Modulated by Hyperglycemia. J Immunol Res. 2019; 2019:5087847.
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Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation. Toxicology. 2018 12 01; 410:1-9.