"A549 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.
| Descriptor ID |
D000072283
|
| MeSH Number(s) |
A11.251.210.190.080 A11.251.860.180.080 A11.436.054
|
| Concept/Terms |
A549 Cells- A549 Cells
- A549 Cell
- Cell, A549
- Cells, A549
- A549 Cell Line
- A549 Cell Lines
- Cell Line, A549
- Cell Lines, A549
|
Below are MeSH descriptors whose meaning is more general than "A549 Cells".
Below are MeSH descriptors whose meaning is more specific than "A549 Cells".
This graph shows the total number of publications written about "A549 Cells" by people in this website by year, and whether "A549 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 4 | 4 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "A549 Cells" by people in Profiles.
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Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression. Cancer Lett. 2021 10 10; 518:230-242.
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XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition. Sci Rep. 2020 08 28; 10(1):14253.
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Analysis of influenza virus-induced perturbation in autophagic flux and its modulation during Vitamin D3 mediated anti-apoptotic signaling. Virus Res. 2020 06; 282:197936.
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Pharmacophore-based designing of putative ROS-1 targeting agents for NSCLC. Mol Divers. 2021 May; 25(2):1091-1102.
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The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma. EMBO Mol Med. 2019 12; 11(12):e10849.
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Paclitaxel-encapsulated core-shell nanoparticle of cetyl alcohol for active targeted delivery through oral route. Nanomedicine (Lond). 2019 08; 14(16):2121-2150.
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Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity. J Pharmacol Exp Ther. 2019 02; 368(2):299-307.
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Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae. PLoS Pathog. 2018 06; 14(6):e1007118.
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Regulation of influenza virus replication by Wnt/ß-catenin signaling. PLoS One. 2018; 13(1):e0191010.
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T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells. PLoS One. 2017; 12(11):e0188288.