"Osteocalcin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
| Descriptor ID |
D015675
|
| MeSH Number(s) |
D12.776.157.125.700
|
| Concept/Terms |
Osteocalcin- Osteocalcin
- Bone gamma-Carboxyglutamic Acid Protein
- Bone gamma Carboxyglutamic Acid Protein
- Vitamin K-Dependent Bone Protein
- Vitamin K Dependent Bone Protein
- Calcium-Binding Protein, Vitamin K-Dependent
- Calcium Binding Protein, Vitamin K Dependent
- Gla Protein, Bone
- 4-Carboxyglutamic Protein, Bone
- 4 Carboxyglutamic Protein, Bone
- Bone 4-Carboxyglutamic Protein
- Protein, Bone 4-Carboxyglutamic
- Bone Gla Protein
- Protein, Bone Gla
|
Below are MeSH descriptors whose meaning is more general than "Osteocalcin".
Below are MeSH descriptors whose meaning is more specific than "Osteocalcin".
This graph shows the total number of publications written about "Osteocalcin" by people in this website by year, and whether "Osteocalcin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Osteocalcin" by people in Profiles.
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On the association between circulating biomarkers and atherosclerotic calcification in a cohort of arterial disease participants. Nutr Metab Cardiovasc Dis. 2021 05 06; 31(5):1533-1541.
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Monitoring Bone Tissue Engineered (BTE) Constructs Based on the Shifting Metabolism of Differentiating Stem Cells. Ann Biomed Eng. 2018 Jan; 46(1):37-47.
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Increasing dietary nitrate has no effect on cancellous bone loss or fecal microbiome in ovariectomized rats. Mol Nutr Food Res. 2017 05; 61(5).
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CD73-generated adenosine promotes osteoblast differentiation. J Cell Physiol. 2012 Jun; 227(6):2622-31.
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Osteogenic differentiation of human umbilical cord mesenchymal stromal cells in polyglycolic acid scaffolds. Tissue Eng Part A. 2010 Jun; 16(6):1937-48.
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Effect of fibronectin- and collagen I-coated titanium fiber mesh on proliferation and differentiation of osteogenic cells. Tissue Eng. 2003 Jun; 9(3):505-15.
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Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. J Bone Miner Res. 2003 May; 18(5):836-43.
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Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12600-5.
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Relationship between estrogen use and musculoskeletal function in postmenopausal women. Maturitas. 2002 Jun 25; 42(2):119-27.
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Musculoskeletal responses to high- and low-intensity resistance training in early postmenopausal women. Med Sci Sports Exerc. 2000 Nov; 32(11):1949-57.