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Mary Beth Humphrey

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentRheumatology/Immunology/Allerg
AddressBRC 256
975 NE 10th St
Oklahoma City OK 73104
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    Collapse Research 
    Collapse research activities and funding
    IS1BX006339     (HUMPHREY, MARY BETH)Mar 1, 2023 - Sep 30, 2023
    NIH
    ShEEP Request for SCANCO microCT
    Role: Principal Investigator
    I01BX006046     (HUMPHREY, MARY BETH)Oct 1, 2022 - Mar 31, 2027
    NIH
    BCCMA: Targeting Osteoarthritis Pain and Progression: Preclinical OA models of vagal nerve stimulation to reduce pain and progression of OA
    Role: Principal Investigator
    RF1AG059717     (ESTUS, STEVEN)Sep 15, 2018 - Mar 31, 2023
    NIH
    Translating SHIP1 genetics to generate a novel Alzheimer's pharmacologic agent
    Role: Co-Principal Investigator
    R01AR064211     (TSIOKAS, LEONIDAS)Sep 17, 2013 - Aug 31, 2019
    NIH
    Calcium Regulation in Osteoclasts
    Role: Co-Principal Investigator
    R01DE019398     (HUMPHREY, MARY BETH)Sep 10, 2008 - Aug 31, 2014
    NIH
    Mechanism of ITAM Signal Regulation in Osteoclasts
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Javed L, Khakwani A, Khan U, Humphrey MB. Medication-induced fractures: Screening and treatment strategies. Am J Med Sci. 2024 Aug 28. PMID: 39214248.
      Citations:    Fields:    
    2. Subramanian A, Vernon KA, Zhou Y, Marshall JL, Alimova M, Arevalo C, Zhang F, Slyper M, Waldman J, Montesinos MS, Dionne D, Nguyen LT, Cuoco MS, Dubinsky D, Purnell J, Keller K, Sturner SH, Grinkevich E, Ghoshal A, Kotek A, Trivioli G, Richoz N, Humphrey MB, Darby IG, Miller SJ, Xu Y, Weins A, Chloe-Villani A, Chang SL, Kretzler M, Rosenblatt-Rosen O, Shaw JL, Zimmerman KA, Clatworthy MR, Regev A, Greka A. Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury. Cell Rep. 2024 Jun 25; 43(6):114253. PMID: 38781074; PMCID: PMC11249042.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Ramakrishnan GS, Berry WL, Pacherille A, Kerr WG, Chisholm JD, Pedicone C, Humphrey MB. SHIP inhibition mediates select TREM2-induced microglial functions. Mol Immunol. 2024 Jun; 170:35-45. PMID: 38613944; PMCID: PMC11097602.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Humphrey MB, Russell L, Danila MI, Fink HA, Guyatt G, Cannon M, Caplan L, Gore S, Grossman J, Hansen KE, Lane NE, Ma NS, Magrey M, McAlindon T, Robinson AB, Saha S, Womack C, Abdulhadi B, Charles JF, Cheah JTL, Chou S, Goyal I, Haseltine K, Jackson L, Mirza R, Moledina I, Punni E, Rinden T, Turgunbaev M, Wysham K, Turner AS, Uhl S. 2022 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Care Res (Hoboken). 2023 Oct 26. PMID: 37884467.
      Citations: 4     Fields:    Translation:Humans
    5. Humphrey MB, Russell L, Danila MI, Fink HA, Guyatt G, Cannon M, Caplan L, Gore S, Grossman J, Hansen KE, Lane NE, Ma NS, Magrey M, McAlindon T, Robinson AB, Saha S, Womack C, Abdulhadi B, Charles JF, Cheah JTL, Chou S, Goyal I, Haseltine K, Jackson L, Mirza R, Moledina I, Punni E, Rinden T, Turgunbaev M, Wysham K, Turner AS, Uhl S. 2022 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Rheumatol. 2023 Oct 16. PMID: 37845798.
      Citations: 14     Fields:    Translation:Humans
    6. Akram B, Khan M, Humphrey MB. HIV-Associated Rheumatic Diseases: A Narrative Review. J Clin Rheumatol. 2023 Sep 19. PMID: 37723618.
      Citations:    Fields:    Translation:HumansCells
    7. Houser JS, Patel M, Wright K, Onopiuk M, Tsiokas L, Humphrey MB. The inhibitor of MyoD Family A (I-MFA) regulates megakaryocyte lineage commitment and terminal differentiation. Blood Cells Mol Dis. 2023 09; 102:102760. PMID: 37267696.
      Citations:    Fields:    Translation:AnimalsCells
    8. Yashchenko A, Bland SJ, Song CJ, Ahmed UKB, Sharp R, Darby IG, Cordova AM, Smith ME, Lever JM, Li Z, Aloria EJ, Khan S, Maryam B, Liu S, Crowley MR, Jones KL, Zenewicz LA, George JF, Mrug M, Crossman DK, Hopp K, Stavrakis S, Humphrey MB, Ginhoux F, Zimmerman KA. Cx3cr1 controls kidney resident macrophage heterogeneity. Front Immunol. 2023; 14:1082078. PMID: 37256130; PMCID: PMC10225589.
      Citations: 1     Fields:    Translation:AnimalsCells
    9. Gentry CA, Thind SK, Williams RJ, Hendrickson SC, Kurdgelashvili G, Humphrey MB. Development of SARS-CoV-2 infection in patients with rheumatic conditions on hydroxychloroquine monotherapy vs. patients without rheumatic conditions: A retrospective, propensity-matched cohort study. Am J Med Sci. 2023 01; 365(1):19-25. PMID: 36103912; PMCID: PMC9464360.
      Citations:    Fields:    Translation:HumansCells
    10. Elkholey K, Niewiadomska M, Morris L, Whyte S, Houser J, Humphrey MB, Stavrakis S. Transcutaneous Vagus Nerve Stimulation Ameliorates the Phenotype of Heart Failure With Preserved Ejection Fraction Through Its Anti-Inflammatory Effects. Circ Heart Fail. 2022 08; 15(8):e009288. PMID: 35862007.
      Citations: 15     Fields:    Translation:HumansAnimals
    11. Stavrakis S, Elkholey K, Morris L, Niewiadomska M, Asad ZUA, Humphrey MB. Neuromodulation of Inflammation to Treat Heart Failure With Preserved Ejection Fraction: A Pilot Randomized Clinical Trial. J Am Heart Assoc. 2022 02; 11(3):e023582. PMID: 35023349.
      Citations: 34     Fields:    Translation:Humans
    12. Petsouki E, Gerakopoulos V, Szeto N, Chang W, Humphrey MB, Tsiokas L. FBW7 couples structural integrity with functional output of primary cilia. Commun Biol. 2021 09 13; 4(1):1066. PMID: 34518642.
      Citations: 4     Translation:AnimalsCells
    13. Elkholey K, Morris L, Niewiadomska M, Houser J, Ramirez M, Tang M, Humphrey MB, Stavrakis S. Sex differences in the incidence and mode of death in rats with heart failure with preserved ejection fraction. Exp Physiol. 2021 03; 106(3):673-682. PMID: 33428276.
      Citations: 6     Fields:    Translation:Animals
    14. Sparling DP, McCullough N, Pajvani U, Humphrey MB. Inhibition of ?-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation. Adipocyte. 2020 12; 9(1):325-334. PMID: 32603641.
      Citations: 1     Fields:    Translation:AnimalsCells
    15. Gentry CA, Humphrey MB, Thind SK, Hendrickson SC, Kurdgelashvili G, Williams RJ. Long-term hydroxychloroquine use in patients with rheumatic conditions and development of SARS-CoV-2 infection: a retrospective cohort study. Lancet Rheumatol. 2020 Nov; 2(11):e689-e697. PMID: 32984847.
      Citations: 28     Fields:    
    16. Onopiuk M, Eby B, Nesin V, Ngo P, Lerner M, Gorvin CM, Stokes VJ, Thakker RV, Brandi ML, Chang W, Humphrey MB, Tsiokas L, Lau K. Control of PTH secretion by the TRPC1 ion channel. JCI Insight. 2020 04 23; 5(8). PMID: 32213715.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    17. Stavrakis S, Stoner JA, Humphrey MB, Morris L, Filiberti A, Reynolds JC, Elkholey K, Javed I, Twidale N, Riha P, Varahan S, Scherlag BJ, Jackman WM, Dasari TW, Po SS. TREAT AF (Transcutaneous Electrical Vagus Nerve Stimulation to Suppress Atrial Fibrillation): A Randomized Clinical Trial. JACC Clin Electrophysiol. 2020 03; 6(3):282-291. PMID: 32192678.
      Citations: 88     Fields:    Translation:Humans
    18. Humphrey MB, Buckley L. Glucocorticoid-Induced Osteoporosis. Reply. N Engl J Med. 2019 04 04; 380(14):1379. PMID: 30943351.
      Citations:    Fields:    Translation:Humans
    19. Buckley L, Humphrey MB. Glucocorticoid-Induced Osteoporosis. N Engl J Med. 2018 Dec 27; 379(26):2547-2556. PMID: 30586507.
      Citations: 115     Fields:    Translation:Humans
    20. Zhou L, Filiberti A, Humphrey MB, Fleming CD, Scherlag BJ, Po SS, Stavrakis S. Low-level transcutaneous vagus nerve stimulation attenuates cardiac remodelling in a rat model of heart failure with preserved ejection fraction. Exp Physiol. 2019 01; 104(1):28-38. PMID: 30398289.
      Citations: 33     Fields:    Translation:Animals
    21. Kalaitzoglou E, Lopes EBP, Fu Y, Herron JC, Flaming JM, Donovan EL, Hu Y, Filiberti A, Griffin TM, Humphrey MB. TLR4 Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice. JBMR Plus. 2019 Apr; 3(4):e10079. PMID: 31044181.
      Citations: 18     
    22. Lopes EBP, Filiberti A, Husain SA, Humphrey MB. Immune Contributions to Osteoarthritis. Curr Osteoporos Rep. 2017 12; 15(6):593-600. PMID: 29098574.
      Citations: 60     Fields:    Translation:HumansCells
    23. Thanou A, Ali T, Haq O, Kaitha S, Morton J, Stavrakis S, Humphrey MB. Corrigendum to "Utilization of Preventive Measures for Glucocorticoid-Induced Osteoporosis among Veterans with Inflammatory Bowel Disease". Int Sch Res Notices. 2017; 2017:2365840. PMID: 29075661.
      Citations:    
    24. Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. A functional genomics predictive network model identifies regulators of inflammatory bowel disease. Nat Genet. 2017 Oct; 49(10):1437-1449. PMID: 28892060.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    25. Heinlen L, Humphrey MB. Skeletal complications of rheumatoid arthritis. Osteoporos Int. 2017 10; 28(10):2801-2812. PMID: 28779302.
      Citations: 21     Fields:    Translation:Humans
    26. Cai X, Xing J, Long CL, Peng Q, Humphrey MB. DOK3 Modulates Bone Remodeling by Negatively Regulating Osteoclastogenesis and Positively Regulating Osteoblastogenesis. J Bone Miner Res. 2017 Nov; 32(11):2207-2218. PMID: 28650106.
      Citations: 10     Fields:    Translation:AnimalsCells
    27. Kalaitzoglou E, Griffin TM, Humphrey MB. Innate Immune Responses and Osteoarthritis. Curr Rheumatol Rep. 2017 Aug; 19(8):45. PMID: 28718060.
      Citations: 54     Fields:    Translation:Humans
    28. Buckley L, Guyatt G, Fink HA, Cannon M, Grossman J, Hansen KE, Humphrey MB, Lane NE, Magrey M, Miller M, Morrison L, Rao M, Robinson AB, Saha S, Wolver S, Bannuru RR, Vaysbrot E, Osani M, Turgunbaev M, Miller AS, McAlindon T. 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Rheumatol. 2017 08; 69(8):1521-1537. PMID: 28585373.
      Citations: 172     Fields:    Translation:Humans
    29. Buckley L, Guyatt G, Fink HA, Cannon M, Grossman J, Hansen KE, Humphrey MB, Lane NE, Magrey M, Miller M, Morrison L, Rao M, Byun Robinson A, Saha S, Wolver S, Bannuru RR, Vaysbrot E, Osani M, Turgunbaev M, Miller AS, McAlindon T. 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Care Res (Hoboken). 2017 08; 69(8):1095-1110. PMID: 28585410.
      Citations: 73     Fields:    Translation:Humans
    30. Stavrakis S, Humphrey MB, Scherlag B, Iftikhar O, Parwani P, Abbas M, Filiberti A, Fleming C, Hu Y, Garabelli P, McUnu A, Peyton M, Po SS. Low-Level Vagus Nerve Stimulation Suppresses Post-Operative Atrial Fibrillation and Inflammation: A Randomized Study. JACC Clin Electrophysiol. 2017 09; 3(9):929-938. PMID: 29759717.
      Citations: 45     Fields:    Translation:Humans
    31. Humphrey MB, Nakamura MC. A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts. Clin Rev Allergy Immunol. 2016 Aug; 51(1):48-58. PMID: 26573914.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    32. Jáuregui EJ, Akil O, Acevedo C, Hall-Glenn F, Tsai BS, Bale HA, Liebenberg E, Humphrey MB, Ritchie RO, Lustig LR, Alliston T. Parallel mechanisms suppress cochlear bone remodeling to protect hearing. Bone. 2016 08; 89:7-15. PMID: 27085457.
      Citations: 18     Fields:    Translation:Animals
    33. Ashpole NM, Herron JC, Estep PN, Logan S, Hodges EL, Yabluchanskiy A, Humphrey MB, Sonntag WE. Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice. Age (Dordr). 2016 Apr; 38(2):38. PMID: 26968399.
      Citations: 14     Fields:    Translation:Animals
    34. Ashpole NM, Herron JC, Mitschelen MC, Farley JA, Logan S, Yan H, Ungvari Z, Hodges EL, Csiszar A, Ikeno Y, Humphrey MB, Sonntag WE. IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. J Bone Miner Res. 2016 Feb; 31(2):443-54. PMID: 26260312.
      Citations: 26     Fields:    Translation:AnimalsCells
    35. Stavrakis S, Humphrey MB, Po SS. Reply: Vagal Modulation of Atrial Fibrillation. J Am Coll Cardiol. 2015 Aug 25; 66(8):978. PMID: 26293771.
      Citations:    Fields:    Translation:Humans
    36. Xing J, Titus AR, Humphrey MB. The TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective. Res Rep Biochem. 2015; 5:89-100. PMID: 26478868.
      Citations: 47     
    37. Stavrakis S, Humphrey MB, Scherlag BJ, Hu Y, Jackman WM, Nakagawa H, Lockwood D, Lazzara R, Po SS. Low-level transcutaneous electrical vagus nerve stimulation suppresses atrial fibrillation. J Am Coll Cardiol. 2015 Mar 10; 65(9):867-75. PMID: 25744003.
      Citations: 136     Fields:    Translation:Humans
    38. Jeffries MA, Donica M, Baker LW, Stevenson ME, Annan AC, Humphrey MB, James JA, Sawalha AH. Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage. Arthritis Rheumatol. 2014 Oct; 66(10):2804-15. PMID: 24980887.
      Citations: 83     Fields:    Translation:HumansCells
    39. Panday K, Gona A, Humphrey MB. Medication-induced osteoporosis: screening and treatment strategies. Ther Adv Musculoskelet Dis. 2014 Oct; 6(5):185-202. PMID: 25342997.
      Citations: 51     
    40. Xing J, Humphrey MB. Editorial: lipid kinases and bone homeostasis: lessons learned from phosphoinositide 3-kinase isoform-specific knockouts. Arthritis Rheumatol. 2014 Aug; 66(8):1984-6. PMID: 24719389.
      Citations:    Fields:    Translation:HumansAnimalsCells
    41. Peng Q, Long CL, Malhotra S, Humphrey MB. A physical interaction between the adaptor proteins DOK3 and DAP12 is required to inhibit lipopolysaccharide signaling in macrophages. Sci Signal. 2013 Aug 20; 6(289):ra72. PMID: 23962980.
      Citations: 33     Fields:    Translation:AnimalsCells
    42. Ong EC, Nesin V, Long CL, Bai CX, Guz JL, Ivanov IP, Abramowitz J, Birnbaumer L, Humphrey MB, Tsiokas L. A TRPC1 protein-dependent pathway regulates osteoclast formation and function. J Biol Chem. 2013 Aug 02; 288(31):22219-32. PMID: 23770672.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    43. Thanou A, Ali T, Haq O, Kaitha S, Morton J, Stavrakis S, Humphrey MB. Utilization of Preventive Measures for Glucocorticoid-Induced Osteoporosis among Veterans with Inflammatory Bowel Disease. ISRN Gastroenterol. 2013; 2013:862312. PMID: 23691340.
      Citations: 3     
    44. Kim C, Kendall MR, Miller MA, Long CL, Larson PR, Humphrey MB, Madden AS, Tas AC. Comparison of titanium soaked in 5 M NaOH or 5 M KOH solutions. Mater Sci Eng C Mater Biol Appl. 2013 Jan 01; 33(1):327-39. PMID: 23565038.
      Citations: 12     Fields:    Translation:AnimalsCells
    45. Li J, Wang JJ, Peng Q, Chen C, Humphrey MB, Heinecke J, Zhang SX. Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy. PLoS One. 2012; 7(12):e52699. PMID: 23285156.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    46. Long CL, Berry WL, Zhao Y, Sun XH, Humphrey MB. E proteins regulate osteoclast maturation and survival. J Bone Miner Res. 2012 Dec; 27(12):2476-89. PMID: 22807064.
      Citations: 5     Fields:    Translation:AnimalsCells
    47. Smith M, Chaudhry MA, Lozano P, Humphrey MB. Cardiac myxoma induced paraneoplastic syndromes: a review of the literature. Eur J Intern Med. 2012 Dec; 23(8):669-73. PMID: 23122392.
      Citations: 8     Translation:Humans
    48. Peng Q, O'Loughlin JL, Humphrey MB. DOK3 negatively regulates LPS responses and endotoxin tolerance. PLoS One. 2012; 7(6):e39967. PMID: 22761938.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    49. Takedachi M, Oohara H, Smith BJ, Iyama M, Kobashi M, Maeda K, Long CL, Humphrey MB, Stoecker BJ, Toyosawa S, Thompson LF, Murakami S. CD73-generated adenosine promotes osteoblast differentiation. J Cell Physiol. 2012 Jun; 227(6):2622-31. PMID: 21882189.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    50. Long CL, Humphrey MB. Osteoimmunology: the expanding role of immunoreceptors in osteoclasts and bone remodeling. Bonekey Rep. 2012 Apr 18; 1. PMID: 23789115.
      Citations: 30     
    51. Smith MJ, Chaudhry MA, Humphrey MB, Lozano PM. Atrial myxoma and bone changes: a paraneoplastic syndrome? J Card Surg. 2011 Jul; 26(4):375-7. PMID: 21793924.
      Citations: 2     Fields:    Translation:Humans
    52. Esplin BL, Shimazu T, Welner RS, Garrett KP, Nie L, Zhang Q, Humphrey MB, Yang Q, Borghesi LA, Kincade PW. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol. 2011 May 01; 186(9):5367-75. PMID: 21441445.
      Citations: 186     Fields:    Translation:AnimalsCells
    53. Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME, Anaya JM, Bae SC, Bang SY, Boackle SA, Brown EE, Petri MA, Gallant C, Ramsey-Goldman R, Reveille JD, Vila LM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Moser KL, Webb CF, Humphrey MB, Montgomery CG, Gaffney PM. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar; 43(3):253-8. PMID: 21336280.
      Citations: 154     Fields:    Translation:HumansCells
    54. Chang JL, Brauer DS, Johnson J, Chen CG, Akil O, Balooch G, Humphrey MB, Chin EN, Porter AE, Butcher K, Ritchie RO, Schneider RA, Lalwani A, Derynck R, Marshall GW, Marshall SJ, Lustig L, Alliston T. Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-ß and Runx2 in bone is required for hearing. EMBO Rep. 2010 Oct; 11(10):765-71. PMID: 20847738.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    55. Peng Q, Malhotra S, Torchia JA, Kerr WG, Coggeshall KM, Humphrey MB. TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal. 2010 May 18; 3(122):ra38. PMID: 20484116.
      Citations: 178     Fields:    Translation:AnimalsCells
    56. Park-Min KH, Ji JD, Antoniv T, Reid AC, Silver RB, Humphrey MB, Nakamura M, Ivashkiv LB. IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression. J Immunol. 2009 Aug 15; 183(4):2444-55. PMID: 19625651.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    57. Ali T, Lam D, Bronze MS, Humphrey MB. Osteoporosis in inflammatory bowel disease. Am J Med. 2009 Jul; 122(7):599-604. PMID: 19559158.
      Citations: 113     Fields:    Translation:HumansPHPublic Health
    58. Bates JS, Lessard CJ, Leon JM, Nguyen T, Battiest LJ, Rodgers J, Kaufman KM, James JA, Gilkeson GS, Kelly JA, Humphrey MB, Harley JB, Gray-McGuire C, Moser KL, Gaffney PM. Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations. Genes Immun. 2009 Jul; 10(5):470-7. PMID: 19387456.
      Citations: 39     Fields:    
    59. Charles JF, Humphrey MB, Zhao X, Quarles E, Nakamura MC, Aderem A, Seaman WE, Smith KD. The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12. Infect Immun. 2008 Jun; 76(6):2439-47. PMID: 18391000.
      Citations: 24     Fields:    Translation:AnimalsCells
    60. Wu Y, Humphrey MB, Nakamura MC. Osteoclasts - the innate immune cells of the bone. Autoimmunity. 2008 Apr; 41(3):183-94. PMID: 18365831.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    61. Wu Y, Torchia J, Yao W, Lane NE, Lanier LL, Nakamura MC, Humphrey MB. Bone microenvironment specific roles of ITAM adapter signaling during bone remodeling induced by acute estrogen-deficiency. PLoS One. 2007 Jul 04; 2(7):e586. PMID: 17611621.
      Citations: 30     Fields:    Translation:AnimalsCells
    62. Hamerman JA, Jarjoura JR, Humphrey MB, Nakamura MC, Seaman WE, Lanier LL. Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J Immunol. 2006 Aug 15; 177(4):2051-5. PMID: 16887962.
      Citations: 214     Fields:    Translation:AnimalsCells
    63. Humphrey MB, Lanier LL, Nakamura MC. Role of ITAM-containing adapter proteins and their receptors in the immune system and bone. Immunol Rev. 2005 Dec; 208:50-65. PMID: 16313340.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    64. Humphrey MB, Daws MR, Spusta SC, Niemi EC, Torchia JA, Lanier LL, Seaman WE, Nakamura MC. TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function. J Bone Miner Res. 2006 Feb; 21(2):237-45. PMID: 16418779.
      Citations: 75     Fields:    Translation:AnimalsCells
    65. Lane NE, Yao W, Nakamura MC, Humphrey MB, Kimmel D, Huang X, Sheppard D, Ross FP, Teitelbaum SL. Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state. J Bone Miner Res. 2005 Jan; 20(1):58-66. PMID: 15619670.
      Citations: 32     Fields:    Translation:AnimalsCells
    66. Mócsai A, Humphrey MB, Van Ziffle JA, Hu Y, Burghardt A, Spusta SC, Majumdar S, Lanier LL, Lowell CA, Nakamura MC. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad Sci U S A. 2004 Apr 20; 101(16):6158-63. PMID: 15073337.
      Citations: 185     Fields:    Translation:AnimalsCells
    67. Humphrey MB, Ogasawara K, Yao W, Spusta SC, Daws MR, Lane NE, Lanier LL, Nakamura MC. The signaling adapter protein DAP12 regulates multinucleation during osteoclast development. J Bone Miner Res. 2004 Feb; 19(2):224-34. PMID: 14969392.
      Citations: 47     Fields:    Translation:AnimalsCells
    68. Chung DH, Humphrey MB, Nakamura MC, Ginzinger DG, Seaman WE, Daws MR. CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. J Immunol. 2003 Dec 15; 171(12):6541-8. PMID: 14662855.
      Citations: 49     Fields:    Translation:AnimalsCells
    69. Humphrey MB, Herrera-Sosa H, Gonzalez G, Lee R, Bryan J. Cloning of cDNAs encoding human caldesmons. Gene. 1992 Mar 15; 112(2):197-204. PMID: 1555769.
      Citations: 24     Fields:    Translation:HumansCells
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