"Nocodazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
| Descriptor ID |
D015739
|
| MeSH Number(s) |
D03.633.100.103.637
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nocodazole".
Below are MeSH descriptors whose meaning is more specific than "Nocodazole".
This graph shows the total number of publications written about "Nocodazole" by people in this website by year, and whether "Nocodazole" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nocodazole" by people in Profiles.
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The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit. Mol Biol Cell. 2014 Mar; 25(5):594-605.
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A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor. Cancer Res. 2009 Feb 15; 69(4):1509-16.
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Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility. J Biol Chem. 2006 Dec 22; 281(51):39719-27.
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The reversibility of mitotic exit in vertebrate cells. Nature. 2006 Apr 13; 440(7086):954-8.
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Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons. Mol Cancer Ther. 2006 Jan; 5(1):29-38.
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Insulin promotes formation of polymerized microtubules by a phosphatidylinositol 3-kinase-independent, actin-dependent pathway in 3T3-L1 adipocytes. Endocrinology. 2003 Nov; 144(11):5030-9.
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Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms. Mol Ther. 2002 Nov; 6(5):637-44.
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Glucose-induced activation of glucose uptake in cells from the inner and outer blood-retinal barrier. Invest Ophthalmol Vis Sci. 2002 Jul; 43(7):2356-63.