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Gary J Gorbsky

TitleMember
InstitutionOklahoma Medical Research Foundation
DepartmentCell Cyle and Cancer Biology Research
Addressn/a
825 N.E. 13th Street
Oklahoma City OK 73104
Phone405/271-8168
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    Collapse Research 
    Collapse research activities and funding
    R35GM126980     (GORBSKY, GARY J.)Jul 1, 2018 - Jun 30, 2023
    NIH
    Understanding Cell Division
    Role: Principal Investigator
    R01GM111731     (GORBSKY, GARY J.)Sep 15, 2014 - Feb 28, 2019
    NIH
    The role of cohesion fatigue in chromosome instability
    Role: Principal Investigator
    S10RR019282     (GORBSKY, GARY J.)May 1, 2004 - Oct 31, 2005
    NIH
    A Cell Dynamics Microscope for Live Cell Fluorescence
    Role: Principal Investigator
    R21CA091264     (GORBSKY, GARY J.)Mar 1, 2001 - Feb 28, 2003
    NIH
    The Spindle Checkpoint as a Target for Cancer
    Role: Principal Investigator
    S10RR012843     (GORBSKY, GARY J.)Mar 1, 1998 - Feb 28, 1999
    NIH
    PROTEIN ABLATION MICROSCOPE
    Role: Principal Investigator
    R01GM050412     (GORBSKY, GARY J.)Jan 1, 1994 - Aug 31, 2014
    NIH
    Chromosome Movement in Prometaphase
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Meyer RE, Sartin A, Gish M, Harsha J, Wilkie E, Haworth D, LaVictoire R, Alberola I, Chuong HH, Gorbsky GJ, Dawson DS. Polyploid yeast are dependent on elevated levels of Mps1 for successful chromosome segregation. bioRxiv. 2023 Jan 10. PMID: 36712123; PMCID: PMC9882063.
      Citations:    
    2. Gorbsky GJ, Daum JR, Sapkota H, Summala K, Yoshida H, Georgescu C, Wren JD, Peshkin L, Horb ME. Developing immortal cell lines from Xenopus embryos, four novel cell lines derived from Xenopus tropicalis. Open Biol. 2022 07; 12(7):220089. PMID: 35857907.
      Citations: 2     Fields:    Translation:AnimalsCells
    3. DuBose CO, Daum JR, Sansam CL, Gorbsky GJ. Dynamic Features of Chromosomal Instability during Culture of Induced Pluripotent Stem Cells. Genes (Basel). 2022 06 27; 13(7). PMID: 35885940.
      Citations: 2     Fields:    Translation:HumansCells
    4. Tipton AR, Gorbsky GJ. More than two populations of microtubules comprise the dynamic mitotic spindle. J Cell Sci. 2022 02 01; 135(3). PMID: 34907446.
      Citations: 1     Fields:    Translation:Cells
    5. Daum JR, DuBose CO, Sivakumar S, Gorbsky GJ. Live Fluorescence Imaging of Chromosome Segregation in Cultured Cells. Methods Mol Biol. 2022; 2415:61-86. PMID: 34972946.
      Citations:    Fields:    Translation:Cells
    6. Laine LJ, Mäki-Jouppila JHE, Kutvonen E, Tiikkainen P, Nyholm TKM, Tien JF, Umbreit NT, Härmä V, Kallio L, Davis TN, Asbury CL, Poso A, Gorbsky GJ, Kallio MJ. VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro. Oncoscience. 2021; 8:134-153. PMID: 34926718.
      Citations:    
    7. Meyer RE, Tipton AR, LaVictoire R, Gorbsky GJ, Dawson DS. Mps1 promotes poleward chromosome movements in meiotic prometaphase. Mol Biol Cell. 2021 05 01; 32(10):1020-1032. PMID: 33788584.
      Citations:    Fields:    Translation:AnimalsCells
    8. Sapkota H, Wren JD, Gorbsky GJ. CSAG1 maintains the integrity of the mitotic centrosome in cells with defective p53. J Cell Sci. 2020 05 27; 133(10). PMID: 32295846.
      Citations: 6     Fields:    Translation:HumansCells
    9. Seibert M, Krüger M, Watson NA, Sen O, Daum JR, Slotman JA, Braun T, Houtsmuller AB, Gorbsky GJ, Jacob R, Kracht M, Higgins JMG, Schmitz ML. CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation. J Cell Biol. 2019 04 01; 218(4):1164-1181. PMID: 30765437.
      Citations: 12     Fields:    Translation:HumansCells
    10. Sapkota H, Wasiak E, Daum JR, Gorbsky GJ. Multiple determinants and consequences of cohesion fatigue in mammalian cells. Mol Biol Cell. 2018 08 01; 29(15):1811-1824. PMID: 29846129.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    11. Fields E, Wren JD, Georgescu C, Daum JR, Gorbsky GJ. Predictive bioinformatics identifies novel regulators of proliferation in a cancer stem cell model. Stem Cell Res. 2018 01; 26:1-7. PMID: 29179130.
      Citations: 5     Fields:    Translation:HumansCells
    12. Sivakumar S, Gorbsky GJ. Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores. Biol Open. 2017 Nov 15; 6(11):1672-1679. PMID: 28982702.
      Citations: 13     Fields:    
    13. Tipton AR, Wren JD, Daum JR, Siefert JC, Gorbsky GJ. GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms. J Cell Biol. 2017 10 02; 216(10):3117-3132. PMID: 28821562.
      Citations: 20     Fields:    Translation:HumansCells
    14. Potapova T, Gorbsky GJ. The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis. Biology (Basel). 2017 Feb 08; 6(1). PMID: 28208750.
      Citations: 66     
    15. Sivakumar S, Janczyk PL, Qu Q, Brautigam CA, Stukenberg PT, Yu H, Gorbsky GJ. The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores. Elife. 2016 Mar 16; 5. PMID: 26981768.
      Citations: 40     Fields:    Translation:HumansCells
    16. Sivakumar S, Gorbsky GJ. Spatiotemporal regulation of the anaphase-promoting complex in mitosis. Nat Rev Mol Cell Biol. 2015 Feb; 16(2):82-94. PMID: 25604195.
      Citations: 148     Fields:    Translation:Humans
    17. Gorbsky GJ. The spindle checkpoint and chromosome segregation in meiosis. FEBS J. 2015 Jul; 282(13):2471-87. PMID: 25470754.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    18. Sivakumar S, Daum JR, Tipton AR, Rankin S, Gorbsky GJ. The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit. Mol Biol Cell. 2014 Mar; 25(5):594-605. PMID: 24403607.
      Citations: 43     Fields:    Translation:HumansCells
    19. Sivakumar S, Daum JR, Gorbsky GJ. Live-cell fluorescence imaging for phenotypic analysis of mitosis. Methods Mol Biol. 2014; 1170:549-62. PMID: 24906336.
      Citations: 7     Fields:    Translation:HumansCells
    20. Gorbsky GJ. Cohesion fatigue. Curr Biol. 2013 Nov 18; 23(22):R986-R988. PMID: 24262830.
      Citations: 17     Fields:    Translation:HumansCells
    21. Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 2013 Apr; 21(2):101-6. PMID: 23580138.
      Citations: 23     Fields:    Translation:HumansCells
    22. Wang F, Ulyanova NP, Daum JR, Patnaik D, Kateneva AV, Gorbsky GJ, Higgins JM. Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation. J Cell Biol. 2012 10 15; 199(2):251-68. PMID: 23071152.
      Citations: 61     Fields:    Translation:HumansCells
    23. Daum JR, Potapova TA, Sivakumar S, Daniel JJ, Flynn JN, Rankin S, Gorbsky GJ. Cohesion fatigue induces chromatid separation in cells delayed at metaphase. Curr Biol. 2011 Jun 21; 21(12):1018-24. PMID: 21658943.
      Citations: 103     Fields:    Translation:HumansCells
    24. Potapova TA, Sivakumar S, Flynn JN, Li R, Gorbsky GJ. Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited. Mol Biol Cell. 2011 Apr 15; 22(8):1191-206. PMID: 21325631.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    25. Wang F, Dai J, Daum JR, Niedzialkowska E, Banerjee B, Stukenberg PT, Gorbsky GJ, Higgins JM. Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science. 2010 10 08; 330(6001):231-5. PMID: 20705812.
      Citations: 250     Fields:    Translation:HumansAnimalsCells
    26. Hu L, Potapova TA, Li S, Rankin S, Gorbsky GJ, Angeletti PC, Ceresa BP. Expression of HPV16 E5 produces enlarged nuclei and polyploidy through endoreplication. Virology. 2010 Sep 30; 405(2):342-51. PMID: 20605566.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    27. Gorbsky GJ. Duct tape for broken chromosomes. Cell. 2010 Jan 22; 140(2):178-80. PMID: 20141831.
      Citations:    Fields:    Translation:AnimalsCells
    28. Daum JR, Wren JD, Daniel JJ, Sivakumar S, McAvoy JN, Potapova TA, Gorbsky GJ. Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis. Curr Biol. 2009 Sep 15; 19(17):1467-72. PMID: 19646878.
      Citations: 112     Fields:    Translation:HumansCells
    29. Salmela AL, Pouwels J, Varis A, Kukkonen AM, Toivonen P, Halonen PK, Perälä M, Kallioniemi O, Gorbsky GJ, Kallio MJ. Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint. Carcinogenesis. 2009 Jun; 30(6):1032-40. PMID: 19395653.
      Citations: 16     Fields:    Translation:HumansCells
    30. Knowlton AL, Vorozhko VV, Lan W, Gorbsky GJ, Stukenberg PT. ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. Curr Biol. 2009 May 12; 19(9):758-63. PMID: 19327998.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    31. DeMoe JH, Santaguida S, Daum JR, Musacchio A, Gorbsky GJ. A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor. Cancer Res. 2009 Feb 15; 69(4):1509-16. PMID: 19190331.
      Citations: 10     Fields:    Translation:HumansCells
    32. Potapova TA, Daum JR, Byrd KS, Gorbsky GJ. Fine tuning the cell cycle: activation of the Cdk1 inhibitory phosphorylation pathway during mitotic exit. Mol Biol Cell. 2009 Mar; 20(6):1737-48. PMID: 19158392.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    33. Daum JR, Mo YY, Gorbsky GJ. The dynamics of DNA topoisomerase IIalpha in living cells. Methods Mol Biol. 2009; 582:233-44. PMID: 19763954.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    34. Hu L, Plafker K, Vorozhko V, Zuna RE, Hanigan MH, Gorbsky GJ, Plafker SM, Angeletti PC, Ceresa BP. Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion. Virology. 2009 Feb 05; 384(1):125-34. PMID: 19041112.
      Citations: 23     Fields:    Translation:HumansCells
    35. Vorozhko VV, Emanuele MJ, Kallio MJ, Stukenberg PT, Gorbsky GJ. Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. Chromosoma. 2008 Apr; 117(2):169-79. PMID: 18057949.
      Citations: 46     Fields:    Translation:AnimalsCells
    36. Pouwels J, Kukkonen AM, Lan W, Daum JR, Gorbsky GJ, Stukenberg T, Kallio MJ. Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1. Cell Cycle. 2007 Jul 01; 6(13):1579-85. PMID: 17617734.
      Citations: 27     Fields:    Translation:HumansCells
    37. Yamada HY, Gorbsky GJ. Spindle checkpoint function and cellular sensitivity to antimitotic drugs. Mol Cancer Ther. 2006 Dec; 5(12):2963-9. PMID: 17172401.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    38. Eyster CA, Duggins QS, Gorbsky GJ, Olson AL. Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility. J Biol Chem. 2006 Dec 22; 281(51):39719-27. PMID: 17068336.
      Citations: 12     Fields:    Translation:AnimalsCells
    39. Potapova TA, Daum JR, Pittman BD, Hudson JR, Jones TN, Satinover DL, Stukenberg PT, Gorbsky GJ. The reversibility of mitotic exit in vertebrate cells. Nature. 2006 Apr 13; 440(7086):954-8. PMID: 16612388.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    40. Yamada HY, Gorbsky GJ. Cell-based expression cloning for identification of polypeptides that hypersensitize mammalian cells to mitotic arrest. Biol Proced Online. 2006; 8:36-43. PMID: 16799695.
      Citations: 1     
    41. Yamada HY, Gorbsky GJ. Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105. Oncogene. 2006 Mar 02; 25(9):1330-9. PMID: 16314844.
      Citations: 13     Fields:    Translation:HumansCells
    42. Daum JR, Gorbsky GJ. Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro. Methods. 2006 Jan; 38(1):52-9. PMID: 16343931.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Yamada HY, Gorbsky GJ. Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons. Mol Cancer Ther. 2006 Jan; 5(1):29-38. PMID: 16432160.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    44. Ahonen LJ, Kallio MJ, Daum JR, Bolton M, Manke IA, Yaffe MB, Stukenberg PT, Gorbsky GJ. Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr Biol. 2005 Jun 21; 15(12):1078-89. PMID: 15964272.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    45. Beardmore VA, Ahonen LJ, Gorbsky GJ, Kallio MJ. Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity. J Cell Sci. 2004 Aug 15; 117(Pt 18):4033-42. PMID: 15280424.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    46. Gorbsky GJ. Mitosis: MCAK under the aura of Aurora B. Curr Biol. 2004 May 04; 14(9):R346-8. PMID: 15120087.
      Citations: 14     Fields:    Translation:Cells
    47. Rundle DR, Gorbsky G, Tsiokas L. PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles. J Biol Chem. 2004 Jul 09; 279(28):29728-39. PMID: 15123714.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    48. McCleland ML, Kallio MJ, Barrett-Wilt GA, Kestner CA, Shabanowitz J, Hunt DF, Gorbsky GJ, Stukenberg PT. The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol. 2004 Jan 20; 14(2):131-7. PMID: 14738735.
      Citations: 90     Fields:    Translation:AnimalsCells
    49. McCleland ML, Gardner RD, Kallio MJ, Daum JR, Gorbsky GJ, Burke DJ, Stukenberg PT. The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev. 2003 Jan 01; 17(1):101-14. PMID: 12514103.
      Citations: 140     Fields:    Translation:AnimalsCells
    50. Kallio MJ, Beardmore VA, Weinstein J, Gorbsky GJ. Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. J Cell Biol. 2002 Sep 02; 158(5):841-7. PMID: 12196507.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    51. Tavormina PA, Côme MG, Hudson JR, Mo YY, Beck WT, Gorbsky GJ. Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis. J Cell Biol. 2002 Jul 08; 158(1):23-9. PMID: 12105179.
      Citations: 61     Fields:    Translation:AnimalsCells
    52. Null AP, Hudson J, Gorbsky GJ. Both alpha and beta isoforms of mammalian DNA topoisomerase II associate with chromosomes in mitosis. Cell Growth Differ. 2002 Jul; 13(7):325-33. PMID: 12133901.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    53. Topper LM, Campbell MS, Tugendreich S, Daum JR, Burke DJ, Hieter P, Gorbsky GJ. The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. Cell Cycle. 2002 Jul-Aug; 1(4):282-92. PMID: 12429948.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    54. Kallio MJ, McCleland ML, Stukenberg PT, Gorbsky GJ. Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol. 2002 Jun 04; 12(11):900-5. PMID: 12062053.
      Citations: 115     Fields:    Translation:AnimalsCells
    55. Giodini A, Kallio MJ, Wall NR, Gorbsky GJ, Tognin S, Marchisio PC, Symons M, Altieri DC. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 2002 May 01; 62(9):2462-7. PMID: 11980633.
      Citations: 78     Fields:    Translation:HumansCells
    56. Messenger MM, Saulnier RB, Gilchrist AD, Diamond P, Gorbsky GJ, Litchfield DW. Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions. J Biol Chem. 2002 Jun 21; 277(25):23054-64. PMID: 11940573.
      Citations: 31     Fields:    Translation:HumansCells
    57. Gorbsky GJ. The mitotic spindle checkpoint. Curr Biol. 2001 Dec 11; 11(24):R1001-4. PMID: 11747833.
      Citations: 20     Fields:    Translation:AnimalsCells
    58. Topper LM, Bastians H, Ruderman JV, Gorbsky GJ. Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes. J Cell Biol. 2001 Aug 20; 154(4):707-17. PMID: 11514588.
      Citations: 7     Fields:    Translation:AnimalsCells
    59. Escargueil AE, Plisov SY, Skladanowski A, Borgne A, Meijer L, Gorbsky GJ, Larsen AK. Recruitment of cdc2 kinase by DNA topoisomerase II is coupled to chromatin remodeling. FASEB J. 2001 Oct; 15(12):2288-90. PMID: 11511510.
      Citations: 10     Fields:    Translation:AnimalsCells
    60. Daum JR, Tugendreich S, Topper LM, Jorgensen PM, Hoog C, Hieter P, Gorbsky GJ. The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome. Curr Biol. 2000 Nov 30; 10(23):R850-2. PMID: 11114529.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    61. Kallio M, Eriksson JE, Gorbsky GJ. Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis. Dev Biol. 2000 Sep 01; 225(1):112-23. PMID: 10964468.
      Citations: 12     Fields:    Translation:Animals
    62. Campbell MS, Daum JR, Gersch MS, Nicklas RB, Gorbsky GJ. Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells. Cell Motil Cytoskeleton. 2000 Jun; 46(2):146-56. PMID: 10891860.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    63. Gorbsky GJ, Kallio M, Daum JR, Topper LM. Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition. FASEB J. 1999 Dec; 13 Suppl 2:S231-4. PMID: 10619133.
      Citations: 2     Fields:    Translation:Cells
    64. Waters JC, Chen RH, Murray AW, Gorbsky GJ, Salmon ED, Nicklas RB. Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis. Curr Biol. 1999 Jun 17; 9(12):649-52. PMID: 10375530.
      Citations: 21     Fields:    Translation:AnimalsCells
    65. Daum JR, Gorbsky GJ. Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody. J Biol Chem. 1998 Nov 13; 273(46):30622-9. PMID: 9804834.
      Citations: 17     Fields:    Translation:HumansCells
    66. Nicklas RB, Campbell MS, Ward SC, Gorbsky GJ. Tension-sensitive kinetochore phosphorylation in vitro. J Cell Sci. 1998 Nov; 111 ( Pt 21):3189-96. PMID: 9763513.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    67. Zecevic M, Catling AD, Eblen ST, Renzi L, Hittle JC, Yen TJ, Gorbsky GJ, Weber MJ. Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E. J Cell Biol. 1998 Sep 21; 142(6):1547-58. PMID: 9744883.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    68. Kallio M, Weinstein J, Daum JR, Burke DJ, Gorbsky GJ. Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. J Cell Biol. 1998 Jun 15; 141(6):1393-406. PMID: 9628895.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    69. Gorbsky GJ, Chen RH, Murray AW. Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase. J Cell Biol. 1998 Jun 01; 141(5):1193-205. PMID: 9606211.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    70. Bousbaa H, Correia L, Gorbsky GJ, Sunkel CE. Mitotic phosphoepitopes are expressed in Kc cells, neuroblasts and isolated chromosomes of Drosophila melanogaster. J Cell Sci. 1997 Sep; 110 ( Pt 17):1979-88. PMID: 9378750.
      Citations: 8     Fields:    Translation:AnimalsCells
    71. Renzi L, Gersch MS, Campbell MS, Wu L, Osmani SA, Gorbsky GJ. MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases. J Cell Sci. 1997 Sep; 110 ( Pt 17):2013-25. PMID: 9378753.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    72. Gorbsky GJ. Cell cycle checkpoints: arresting progress in mitosis. Bioessays. 1997 Mar; 19(3):193-7. PMID: 9103187.
      Citations: 15     Fields:    Translation:HumansAnimals
    73. Campbell MS, Lovell MA, Gorbsky GJ. Stability of nuclear segments in human neutrophils and evidence against a role for microfilaments or microtubules in their genesis during differentiation of HL60 myelocytes. J Leukoc Biol. 1995 Dec; 58(6):659-66. PMID: 7499963.
      Citations: 15     Fields:    Translation:HumansCells
    74. Taagepera S, Campbell MS, Gorbsky GJ. Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes. Exp Cell Res. 1995 Nov; 221(1):249-60. PMID: 7589252.
      Citations: 3     Fields:    Translation:AnimalsCells
    75. Nicklas RB, Ward SC, Gorbsky GJ. Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint. J Cell Biol. 1995 Aug; 130(4):929-39. PMID: 7642708.
      Citations: 117     Fields:    Translation:AnimalsCells
    76. Campbell MS, Gorbsky GJ. Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase. J Cell Biol. 1995 Jun; 129(5):1195-204. PMID: 7775567.
      Citations: 42     Fields:    Translation:AnimalsCells
    77. Gorbsky GJ. Kinetochores, microtubules and the metaphase checkpoint. Trends Cell Biol. 1995 Apr; 5(4):143-8. PMID: 14732139.
      Citations: 19     Fields:    
    78. Taagepera S, Dent P, Her JH, Sturgill TW, Gorbsky GJ. The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183. Mol Biol Cell. 1994 Nov; 5(11):1243-51. PMID: 7532473.
      Citations: 5     Fields:    Translation:AnimalsCells
    79. Gorbsky GJ. Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane). Cancer Res. 1994 Feb 15; 54(4):1042-8. PMID: 8313360.
      Citations: 36     Fields:    Translation:AnimalsCells
    80. Taagepera S, Rao PN, Drake FH, Gorbsky GJ. DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8407-11. PMID: 7690961.
      Citations: 61     Fields:    Translation:AnimalsCells
    81. Gorbsky GJ, Ricketts WA. Differential expression of a phosphoepitope at the kinetochores of moving chromosomes. J Cell Biol. 1993 Sep; 122(6):1311-21. PMID: 7690762.
      Citations: 76     Fields:    Translation:AnimalsCells
    82. Gorbsky GJ. Chromosome motion in mitosis. Bioessays. 1992 Feb; 14(2):73-80. PMID: 1575715.
      Citations: 16     Fields:    Translation:Cells
    83. Gorbsky GJ, Simerly C, Schatten G, Borisy GG. Microtubules in the metaphase-arrested mouse oocyte turn over rapidly. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6049-53. PMID: 2385583.
      Citations: 15     Fields:    Translation:AnimalsCells
    84. Gorbsky GJ, Borisy GG. Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase. J Cell Biol. 1989 Aug; 109(2):653-62. PMID: 2668301.
      Citations: 34     Fields:    Translation:AnimalsCells
    85. Gorbsky GJ, Borisy GG. Microtubule dynamics and the movement of chromosomes. Prog Clin Biol Res. 1989; 318:159-69. PMID: 2696965.
      Citations:    Fields:    Translation:AnimalsCells
    86. Gorbsky GJ, Borisy GG. Hapten-mediated immunocytochemistry: the use of fluorescent and nonfluorescent haptens for the study of cytoskeletal dynamics in living cells. Methods Cell Biol. 1989; 29:175-93. PMID: 2643759.
      Citations:    Fields:    Translation:AnimalsCells
    87. Gorbsky GJ, Sammak PJ, Borisy GG. Microtubule dynamics and chromosome motion visualized in living anaphase cells. J Cell Biol. 1988 Apr; 106(4):1185-92. PMID: 3283149.
      Citations: 44     Fields:    Translation:AnimalsCells
    88. Sammak PJ, Gorbsky GJ, Borisy GG. Microtubule dynamics in vivo: a test of mechanisms of turnover. J Cell Biol. 1987 Mar; 104(3):395-405. PMID: 3546333.
      Citations: 43     Fields:    Translation:HumansCells
    89. Gorbsky GJ, Sammak PJ, Borisy GG. Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends. J Cell Biol. 1987 Jan; 104(1):9-18. PMID: 3793763.
      Citations: 112     Fields:    Translation:AnimalsCells
    90. Gorbsky G, Borisy GG. Reversible embedment cytochemistry (REC): a versatile method for the ultrastructural analysis and affinity labeling of tissue sections. J Histochem Cytochem. 1986 Feb; 34(2):177-88. PMID: 3511139.
      Citations: 1     Fields:    Translation:Animals
    91. Gorbsky G. Intercellular recognition and adhesion in desmosomes. Dev Biol (N Y 1985). 1986; 3:129-56. PMID: 3077961.
      Citations:    Fields:    Translation:HumansAnimalsCells
    92. Gorbsky G, Borisy GG. Microtubule distribution in cultured cells and intact tissues: improved immunolabeling resolution through the use of reversible embedment cytochemistry. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6889-93. PMID: 3901009.
      Citations: 14     Fields:    Translation:AnimalsCells
    93. Gorbsky G, Cohen SM, Shida H, Giudice GJ, Steinberg MS. Isolation of the non-glycosylated proteins of desmosomes and immunolocalization of a third plaque protein: desmoplakin III. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):810-4. PMID: 3883348.
      Citations: 20     Fields:    Translation:AnimalsCells
    94. Gorbsky G, Cohen S, Steinberg MS. Desmosomal antigens are not recognized by the majority of pemphigus autoimmune sera. J Invest Dermatol. 1983 Jun; 80(6):475-80. PMID: 6343511.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    95. Cohen SM, Gorbsky G, Steinberg MS. Immunochemical characterization of related families of glycoproteins in desmosomes. J Biol Chem. 1983 Feb 25; 258(4):2621-7. PMID: 6185499.
      Citations: 34     Fields:    Translation:AnimalsCells
    96. Shida H, Shida M, Gorbsky G, Steinberg MS. Electron microscopic localization of specific carbohydrate groups in thin sections of tissues embedded in a hydrophilic resin: concanavalin A receptors in mouse spleen. J Histochem Cytochem. 1982 Nov; 30(11):1153-64. PMID: 6815263.
      Citations:    Fields:    Translation:AnimalsCells
    97. Shida H, Gorbsky G, Shida M, Steinberg MS. Ultrastructural and biochemical identification of Con A receptors in the desmosome. J Cell Biochem. 1982; 20(2):113-26. PMID: 7169495.
      Citations: 3     Fields:    Translation:AnimalsCells
    98. Gorbsky G, Steinberg MS. Isolation of the intercellular glycoproteins of desmosomes. J Cell Biol. 1981 Jul; 90(1):243-8. PMID: 6166625.
      Citations: 64     Fields:    Translation:AnimalsCells
    99. Wiseman LL, Gorbsky GJ, Melester TS. Is the movement of single cells within solid tissue masses induced by trypsinization? Exp Cell Res. 1976 Dec; 103(2):426-31. PMID: 1033836.
      Citations: 2     Fields:    Translation:AnimalsCells
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