"Streptolysins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Exotoxins produced by certain strains of streptococci, particularly those of group A (STREPTOCOCCUS PYOGENES), that cause HEMOLYSIS.
Below are MeSH descriptors whose meaning is more general than "Streptolysins".
Below are MeSH descriptors whose meaning is more specific than "Streptolysins".
This graph shows the total number of publications written about "Streptolysins" by people in this website by year, and whether "Streptolysins" was a major or minor topic of these publications.
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|Year||Major Topic||Minor Topic||Total|
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Below are the most recent publications written about "Streptolysins" by people in Profiles.
Immunotherapy targeting the Streptococcus pyogenes M protein or streptolysin O to treat or prevent influenza A superinfection. PLoS One. 2020; 15(6):e0235139.
Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid. Vaccine. 2021 03 12; 39(11):1652-1660.
Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. J Immunol. 2020 01 01; 204(1):101-111.
Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Sci Rep. 2015 Sep 25; 5:14352.
Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection. Clin Vaccine Immunol. 2015 Oct; 22(10):1079-89.
The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support ß-Barrel Pore Insertion. J Biol Chem. 2015 Jul 17; 290(29):17733-17744.
An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2204-9.
Cardiac myocyte dysfunction induced by streptolysin O is membrane pore and calcium dependent. Shock. 2015 Feb; 43(2):178-84.
Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. PLoS Pathog. 2014 Sep; 10(9):e1004353.
The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. PLoS One. 2014; 9(8):e103625.