"Substantia Nigra" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
| Descriptor ID |
D013378
|
| MeSH Number(s) |
A08.186.211.132.659.413.656
|
| Concept/Terms |
Substantia Nigra- Substantia Nigra
- Nigra, Substantia
- Nigras, Substantia
- Substantia Nigras
|
Below are MeSH descriptors whose meaning is more general than "Substantia Nigra".
Below are MeSH descriptors whose meaning is more specific than "Substantia Nigra".
This graph shows the total number of publications written about "Substantia Nigra" by people in this website by year, and whether "Substantia Nigra" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Substantia Nigra" by people in Profiles.
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Preservation of dendritic D2 receptor transmission in substantia nigra dopamine neurons with age. Sci Rep. 2023 01 19; 13(1):1025.
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Neurotensin Release from Dopamine Neurons Drives Long-Term Depression of Substantia Nigra Dopamine Signaling. J Neurosci. 2022 08 10; 42(32):6186-6194.
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Brain Selective Estrogen Treatment Protects Dopaminergic Neurons and Preserves Behavioral Function in MPTP-induced Mouse Model of Parkinson's Disease. J Neuroimmune Pharmacol. 2021 09; 16(3):667-678.
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Progressively disrupted somatodendritic morphology in dopamine neurons in a mouse Parkinson's model. Mov Disord. 2018 12; 33(12):1928-1937.
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Methamphetamine self-administration in mice decreases GIRK channel-mediated currents in midbrain dopamine neurons. Int J Neuropsychopharmacol. 2014 Oct 31; 18(5).