XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Sureban SM, May R, Weygant N, Qu D, Chandrakesan P, Bannerman-Menson E, Ali N, Pantazis P, Westphalen CB, Wang TC, Houchen CW. XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. Cancer Lett. 2014 Aug 28; 351(1):151-61.
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Animals
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Animals
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Antineoplastic Agents
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Antineoplastic Agents
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Benzodiazepinones
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Benzodiazepinones
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Carcinoma, Pancreatic Ductal
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Carcinoma, Pancreatic Ductal
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Cell Line, Tumor
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Cell Line, Tumor
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Cell Proliferation
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Cell Proliferation
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Epithelial-Mesenchymal Transition
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Epithelial-Mesenchymal Transition
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Gene Expression
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Gene Expression
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Intracellular Signaling Peptides and Proteins
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Intracellular Signaling Peptides and Proteins
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Mice
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Mice
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Mice, Inbred NOD
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Mice, Inbred NOD
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Mice, SCID
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Mice, SCID
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MicroRNAs
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MicroRNAs
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Pancreatic Neoplasms
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Pancreatic Neoplasms
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-myc
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Proto-Oncogene Proteins c-myc
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Proto-Oncogene Proteins p21(ras)
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Proto-Oncogene Proteins p21(ras)
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ras Proteins
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ras Proteins
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Receptor, Notch1
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Receptor, Notch1
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RNA, Messenger
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RNA, Messenger
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RNA-Binding Proteins
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RNA-Binding Proteins
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Tumor Burden
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Tumor Burden
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Xenograft Model Antitumor Assays
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Xenograft Model Antitumor Assays