"ras Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D018631
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.500 D12.644.360.525.500 D12.776.157.325.515.500 D12.776.476.525.500
|
| Concept/Terms |
ras Proteins- ras Proteins
- ras GTPases
- GTPases, ras
- Gene Products, ras
- ras Gene Products
|
Below are MeSH descriptors whose meaning is more general than "ras Proteins".
Below are MeSH descriptors whose meaning is more specific than "ras Proteins".
This graph shows the total number of publications written about "ras Proteins" by people in this website by year, and whether "ras Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 1 | 3 |
| 2001 | 1 | 2 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 3 | 0 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 2 | 3 | 5 |
| 2012 | 3 | 2 | 5 |
| 2013 | 0 | 2 | 2 |
| 2014 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "ras Proteins" by people in Profiles.
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Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses. Cell Rep. 2019 10 15; 29(3):573-588.e7.
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Role of molecular markers to predict distant metastasis in papillary thyroid carcinoma: Promising value of TERT promoter mutations and insignificant role of BRAF mutations-a meta-analysis. Tumour Biol. 2017 Oct; 39(10):1010428317713913.
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Paediatric follicular thyroid carcinoma - indolent cancer with low prevalence of RAS mutations and absence of PAX8-PPARG fusion in a Japanese population. Histopathology. 2017 Nov; 71(5):760-768.
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Genetic alterations of differentiated thyroid carcinoma in iodine-rich and iodine-deficient countries. Cancer Med. 2016 08; 5(8):1883-9.
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SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1. EMBO Rep. 2015 Jan; 16(1):87-96.
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Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: novel therapeutic strategy for aggressive breast cancers. Mol Cancer Ther. 2014 Dec; 13(12):3198-3209.
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XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. Cancer Lett. 2014 Aug 28; 351(1):151-61.
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The gep proto-oncogene Ga12 mediates LPA-stimulated activation of CREB in ovarian cancer cells. Cell Signal. 2014 Jan; 26(1):122-32.
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Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors. Pancreas. 2013 Apr; 42(3):411-21.
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Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncol. 2013 Feb; 14(2):134-40.