"Genes, erbB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
| Descriptor ID |
D018815
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.295
|
| Concept/Terms |
c-erbB-3 Genes- c-erbB-3 Genes
- Genes, c-erbB-3
- c erbB 3 Genes
- c-erbB-3 Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, erbB".
Below are MeSH descriptors whose meaning is more specific than "Genes, erbB".
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Below are the most recent publications written about "Genes, erbB" by people in Profiles.
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The epidermal growth factor receptor family: biology driving targeted therapeutics. Cell Mol Life Sci. 2008 May; 65(10):1566-84.